3 hotels near Santee, SC 29142, USA match your filters

3 hotels near Santee, SC 29142, USA match your filters

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  • 30

    Quality Inn & Suites Santee I-95

    1.74 km from destination

    2.43 stars rating. Fair. 272 reviews
    Save 6%
    Strikethrough Rate:$69Discounted rate:$65USD/night
    Member Rate
    Fees included
  • 19

    Quality Inn Manning I-95

    33.94 km from destination

    3.91 stars rating. Good. 139 reviews
    Save 7%
    Strikethrough Rate:$85Discounted rate:$79USD/night
    Member Rate
  • 34

    Quality Inn & Suites Orangeburg

    32.79 km from destination

    3.46 stars rating. Good. 1789 reviews
    Save 5%
    Strikethrough Rate:$73Discounted rate:$69USD/night
    Member Rate
Below are additional hotels in the area that do not match your exact search criteria.
  • 24

    Comfort Inn & Suites Santee I-95

    1.49 km from destination

    3.93 stars rating. Good. 1754 reviews
    Save 10%
    Strikethrough Rate:$127Discounted rate:$114USD/night
    Member Rate
  • 25

    Econo Lodge Santee

    2.13 km from destination

    3 stars rating. Fair. 169 reviews
    Save 7%
    Strikethrough Rate:$74Discounted rate:$69USD/night
    Member Rate
  • 30

    Suburban Studios Orangeburg

    32.87 km from destination

    4.35 stars rating. Excellent. 145 reviews
    Save 5%
    Strikethrough Rate:$89Discounted rate:$85USD/night
    Member Rate
  • 30

    Sleep Inn Orangeburg

    32.77 km from destination

    3.88 stars rating. Good. 1330 reviews
    Save 19%
    Strikethrough Rate:$105Discounted rate:$85USD/night
    Member Rate
  • 30

    Comfort Inn & Suites Orangeburg

    32.61 km from destination

    3.92 stars rating. Good. 1660 reviews
    Save 16%
    Strikethrough Rate:$119Discounted rate:$100USD/night
    Member Rate
  • 32

    Econo Lodge St. George

    32.89 km from destination

    3.08 stars rating. 371 reviews
    Save 7%
    Strikethrough Rate:$69Discounted rate:$64USD/night
    Member Rate

Santee Travel Tips

Santee Hotels

Discover this small South Carolina town—popular with golfers and nature lovers— when you check out our Santee travel guide.

Santee Hotels

Book with Choice Hotels in Santee, SC for an adventure-filled trip any time of year. Known for its golf and fishing, the resort town of Santee, SC is a prime destination for outdoor fun. But when you're ready to head indoors, there is plenty to keep you entertained. Spend the day enjoying the town's natural beauty with a wide range of activities. Then, feast on flavorful Southern cuisine and take your pick of live music venues. After you arrive to your hotel in Santee, check out the most popular attractions, including: Wyboo Golf Club, Palmetto Trail, Clarke's Restaurant and Pub, Santee General Store, Santee Cooper Lakes System and LT's Restaurant and Nite Life.

Golfers should waste no time getting to the links at one of Santee's 11 spectacular courses, including the prestigious Wyboo Golf Club. Frequented by golfers of varying ages and experience, this public golf course features an interesting mix of lateral water, sloping greens and well-placed bunkers. All types of outdoor enthusiasts will enjoy the adventures on Palmetto Trail. Stretching 13 miles in Santee alone, the trail, with its picturesque natural beauty, is the perfect place for biking, hiking or camping. After working up an appetite, head to Clarke's Restaurant and Pub, where your mouth will water at the sight and aroma of authentic Southern cooking. Enjoy fine food and spirits in this cozy fireside atmosphere. Top off your meal with a hand-dipped ice cream cone at the nostalgic Santee General Store, where you can also shop for souvenirs and other items. A town landmark, this charmingly quaint store stocks a good selection of jellies, preserves, ciders, dressings and much more.

Visitors who enjoy fishing can have a great time year round in the Santee Cooper Lakes System, which consists of the vast Lake Moultrie and the cypress-dotted Lake Marion. These lakes are filled with all sorts of exciting catches—from channel catfish to striped bass to shellcracker—and currently hold several state records. When the sun goes down, dance the night away after a delectable dinner at LT's Restaurant and Nite Life. A popular spot with a casual atmosphere, LT's lounge, which offers live entertainment, is open Thursday, Friday and Saturday while the restaurant is open nightly. 

Before your visit, be sure to reserve a room with Choice Hotels in Santee, SC, where you will be near everything the town has to offer.

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Good to know

Number of hotels

3 of 9 hotels in Santee

Highest Price

$114

Lowest Price

$64

Avg. rating

3.6 (7629 reviews)