Hotels in Santa Fe, TX – Choice Hotels

Comfort Inn & Suites Texas City I-45
10700 Emmett F. Lowry Expwy,
Texas City, TX, 77591, US
8.02 km from Santa Fe, TX, USA
2.12 stars rating. Fair. 41 reviews2.12 stars rating. Fair. 41 reviews
Book Now & Save 6%
Strikethrough Rate:~~$77~~Discounted rate:$72USD/night
Member Rate
See Availability
Quality Inn Texas City I-45
2320 FM 2004,
Texas City, TX, 77591, US
8.06 km from Santa Fe, TX, USA
3.51 stars rating. Good. 473 reviews3.51 stars rating. Good. 473 reviews
Book Now & Save 6%
Strikethrough Rate:~~$70~~Discounted rate:$65USD/night
Member Rate
See Availability
EXTENDED STAY
MainStay Suites Houston NASA/Clear Lake
1050 Bay Area Blvd,
Houston, TX, 77058, US
19.73 km from Santa Fe, TX, USA
3.48 stars rating. Good. 101 reviews3.48 stars rating. Good. 101 reviews
Book Now & Save 6%
Strikethrough Rate:~~$79~~Discounted rate:$74USD/night
Member Rate
See Availability
Comfort Suites Seabrook - Kemah
5755 Bayport Blvd,
Seabrook, TX, 77586, US
24.85 km from Santa Fe, TX, USA
3.25 stars rating. Good. 267 reviews3.25 stars rating. Good. 267 reviews
Book Now & Save 33%
Strikethrough Rate:~~$79~~Discounted rate:$54USD/night
Member Rate
See Availability
Stay Longer. Save More.
Say hello to WoodSpring Suites® hotels! Designed for longer stays, we offer contemporary suites with in-room kitchens and free WiFi. Plus, our affordable rates cost less per night when you stay a week, month or more.
See More Hotels
Comfort Suites near NASA - Clear Lake
16931 N. Texas Ave,
Webster, TX, 77598, US
18.44 km from Santa Fe, TX, USA
3.88 stars rating. Good. 1157 reviews3.88 stars rating. Good. 1157 reviews
Book Now & Save 19%
Strikethrough Rate:~~$86~~Discounted rate:$69USD/night
Member Rate
See Availability
AWARD WINNER
Quality Inn & Suites Seabrook- NASA- Kemah
2720 Nasa Parkway,
Seabrook, TX, 77586, US
21.3 km from Santa Fe, TX, USA
4.4 stars rating. Excellent. 1227 reviews4.4 stars rating. Excellent. 1227 reviews
Book Now & Save 10%
Strikethrough Rate:~~$94~~Discounted rate:$84USD/night
Member Rate
See Availability
Rodeway Inn South Houston
2042 Houston Blvd.,
South Houston, TX, 77587, US
32.91 km from Santa Fe, TX, USA
2.97 stars rating. Fair. 118 reviews2.97 stars rating. Fair. 118 reviews
Book Now & Save 6%
Strikethrough Rate:~~$57~~Discounted rate:$53USD/night
Member Rate
See Availability
Quality Inn Houston East I-10
828 Mercury Drive,
Houston, TX, 77013, US
46.14 km from Santa Fe, TX, USA
2.97 stars rating. Fair. 456 reviews2.97 stars rating. Fair. 456 reviews
Book Now & Save 5%
Strikethrough Rate:~~$58~~Discounted rate:$55USD/night
Member Rate
See Availability
EXTENDED STAY
MainStay Suites Texas Medical Center/Reliant Park
3134 Old Spanish Trail,
Houston, TX, 77054, US
44.4 km from Santa Fe, TX, USA
3.96 stars rating. Good. 2363 reviews3.96 stars rating. Good. 2363 reviews
Book Now & Save 7%
Strikethrough Rate:~~$84~~Discounted rate:$78USD/night
Member Rate
See Availability
Quality Inn & Suites Galveston - Beachfront
5924 Seawall Blvd.,
Galveston, TX, 77551, US
29.92 km from Santa Fe, TX, USA
4.04 stars rating. Very Good. 3193 reviews4.04 stars rating. Very Good. 3193 reviews
Book Now & Save 28%
Strikethrough Rate:~~$93~~Discounted rate:$67USD/night
Member Rate
See Availability
FULLY RENOVATED
Clarion Pointe Galveston - Beachfront
5914 Seawall Blvd,
Galveston, TX, 77551, US
29.96 km from Santa Fe, TX, USA
3.85 stars rating. Good. 13 reviews3.85 stars rating. Good. 13 reviews
Book Now & Save 28%
Strikethrough Rate:~~$95~~Discounted rate:$68USD/night
Member Rate
See Availability
Econo Lodge Inn & Suites East Houston I-10
1016 Maxey Road,
Houston, TX, 77015, US
45 km from Santa Fe, TX, USA
4.04 stars rating. Very Good. 387 reviews4.04 stars rating. Very Good. 387 reviews
Book Now & Save 10%
Strikethrough Rate:~~$70~~Discounted rate:$63USD/night
Member Rate
See Availability
Comfort Suites Galveston Cruise Port Area - Beachside
3606 89th Street,
Galveston, TX, 77554, US
28.22 km from Santa Fe, TX, USA
3.47 stars rating. Good. 1689 reviews3.47 stars rating. Good. 1689 reviews
Book Now & Save 24%
Strikethrough Rate:~~$119~~Discounted rate:$91USD/night
Member Rate
See Availability
Econo Lodge Galveston Seawall
3008 Seawall Blvd,
Galveston, TX, 77550-7677, US
31.85 km from Santa Fe, TX, USA
2.75 stars rating. Fair. 122 reviews2.75 stars rating. Fair. 122 reviews
Book Now & Save 30%
Strikethrough Rate:~~$80~~Discounted rate:$56USD/night
Special Rate
See Availability
Comfort Suites Deer Park Pasadena
1501 Center St.,
Deer Park, TX, 77536, US
35.53 km from Santa Fe, TX, USA
3.95 stars rating. Good. 578 reviews3.95 stars rating. Good. 578 reviews
Book Now & Save 21%
Strikethrough Rate:~~$83~~Discounted rate:$66USD/night
Member Rate
See Availability
Sleep Inn & Suites Galveston Island
6628 Broadway Street,
Galveston, TX, 77554, US
27.01 km from Santa Fe, TX, USA
2.95 stars rating. Fair. 859 reviews2.95 stars rating. Fair. 859 reviews
Book Now & Save 6%
Strikethrough Rate:~~$80~~Discounted rate:$75USD/night
Member Rate
See Availability
Quality Suites Houston Hobby Airport
7775 Airport Blvd,
Houston, TX, 77061, US
35.39 km from Santa Fe, TX, USA
3.94 stars rating. Good. 221 reviews3.94 stars rating. Good. 221 reviews
Book Now & Save 19%
Strikethrough Rate:~~$74~~Discounted rate:$60USD/night
Member Rate
See Availability
Comfort Suites La Porte - Baytown
902 South 8th Street,
La Porte, TX, 77571, US
31.56 km from Santa Fe, TX, USA
4.2 stars rating. Excellent. 685 reviews4.2 stars rating. Excellent. 685 reviews
Book Now & Save 24%
Strikethrough Rate:~~$108~~Discounted rate:$82USD/night
Member Rate
See Availability
Comfort Suites Channelview - Houston East
15813 2nd Street,
Channelview, TX, 77530, US
44.61 km from Santa Fe, TX, USA
3.3 stars rating. Good. 299 reviews3.3 stars rating. Good. 299 reviews
Book Now & Save 6%
Strikethrough Rate:~~$67~~Discounted rate:$63USD/night
Member Rate
See Availability
Econo Lodge Inn & Suites Channelview - Houston East
16007 East Fwy,
Channelview, TX, 77530, US
44.72 km from Santa Fe, TX, USA
3.56 stars rating. Good. 18 reviews3.56 stars rating. Good. 18 reviews
Book Now & Save 6%
Strikethrough Rate:~~$59~~Discounted rate:$55USD/night
Member Rate
See Availability
Quality Inn Pasadena - Houston East
114 S. Richey St.,
Pasadena, TX, 77506, US
38.61 km from Santa Fe, TX, USA
3.82 stars rating. Good. 314 reviews3.82 stars rating. Good. 314 reviews
Book Now & Save 30%
Strikethrough Rate:~~$80~~Discounted rate:$56USD/night
Member Rate
See Availability
Sleep Inn & Suites Pearland - Houston South
1908 Country Place Parkway,
Pearland, TX, 77584, US
34.82 km from Santa Fe, TX, USA
3.97 stars rating. Good. 661 reviews3.97 stars rating. Good. 661 reviews
Book Now & Save 10%
Strikethrough Rate:~~$92~~Discounted rate:$83USD/night
Member Rate
See Availability
Comfort Inn & Suites Galveston Central Island near Pier
2818 Avenue R 1 2,
Galveston, TX, 77550, US
31.92 km from Santa Fe, TX, USA
3.28 stars rating. Good. 239 reviews3.28 stars rating. Good. 239 reviews
Book Now & Save 6%
Strikethrough Rate:~~$101~~Discounted rate:$95USD/night
Member Rate
See Availability
Comfort Suites Houston near Medical Center- NRG Stadium
1055 McNee Road, East of Main Street,
Houston, TX, 77054, US
45.84 km from Santa Fe, TX, USA
4.32 stars rating. Excellent. 1799 reviews4.32 stars rating. Excellent. 1799 reviews
Book Now & Save 6%
Strikethrough Rate:~~$113~~Discounted rate:$106USD/night
Member Rate
See Availability
Quality Inn & Suites NRG Park - Medical Center
2364 South Loop West,
Houston, TX, 77054, US
44.82 km from Santa Fe, TX, USA
3.02 stars rating. 1472 reviews3.02 stars rating. 1472 reviews
Book Now & Save 10%
Strikethrough Rate:~~$70~~Discounted rate:$63USD/night
Member Rate
See Availability

Change your dates to book properties below.

NEW HOTEL
Seabreeze Hotel, an Ascend Collection Hotel
2311 Avenue P 1 2,
Galveston, TX, 77550, US
32.22 km from Santa Fe, TX, USA
4.48 stars rating. Excellent. 65 reviews4.48 stars rating. Excellent. 65 reviews
Sold outfor your selected dates
See Availability

Good to know

Number of hotels

26 hotels in Santa Fe

Highest Price

$106

Lowest Price

$53

Avg. rating

25 hotels near Santa Fe, TX, USA

Comfort Inn & Suites Texas City I-45

Quality Inn Texas City I-45

MainStay Suites Houston NASA/Clear Lake

Comfort Suites Seabrook - Kemah

Stay Longer. Save More.

Comfort Suites near NASA - Clear Lake

Quality Inn & Suites Seabrook- NASA- Kemah

Rodeway Inn South Houston

Quality Inn Houston East I-10

MainStay Suites Texas Medical Center/Reliant Park

Quality Inn & Suites Galveston - Beachfront

Clarion Pointe Galveston - Beachfront

Econo Lodge Inn & Suites East Houston I-10

Comfort Suites Galveston Cruise Port Area - Beachside

Econo Lodge Galveston Seawall

Comfort Suites Deer Park Pasadena

Sleep Inn & Suites Galveston Island

Quality Suites Houston Hobby Airport

Comfort Suites La Porte - Baytown

Comfort Suites Channelview - Houston East

Econo Lodge Inn & Suites Channelview - Houston East

Quality Inn Pasadena - Houston East

Sleep Inn & Suites Pearland - Houston South

Comfort Inn & Suites Galveston Central Island near Pier

Comfort Suites Houston near Medical Center- NRG Stadium

Quality Inn & Suites NRG Park - Medical Center

Change your dates to book properties below.

Seabreeze Hotel, an Ascend Collection Hotel

Other Santa Fe searches

Good to know

26 hotels in Santa Fe

$106

$53

3.6 (18817 reviews)