Book Top Rated Hotels in Cape Girardeau, MO | Choice Hotels

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Quality Inn Cairo I-57
13201 Kessler Rd, Route 3 and I-57,
Cairo, IL, 62914, US
25.43 mi from Cape Girardeau, MO, USA
3.66 stars rating. Good. 557 reviews3.66 stars rating. Good. 557 reviews
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Comfort Inn & Suites Sikeston I-55
109 Matthews Lane,
Sikeston, MO, 63801, US
28.73 mi from Cape Girardeau, MO, USA
4.02 stars rating. Very Good. 1339 reviews4.02 stars rating. Very Good. 1339 reviews
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Quality Inn Charleston - Sikeston
102 Drake St., I-57 ex. 10,
Charleston, MO, 63834, US
28.93 mi from Cape Girardeau, MO, USA
3.37 stars rating. Good. 621 reviews3.37 stars rating. Good. 621 reviews
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Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Road,
Jackson, MO, 63755, US
6.07 mi from Cape Girardeau, MO, USA
3.87 stars rating. Good. 1493 reviews3.87 stars rating. Good. 1493 reviews
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Quality Inn
2011 N. Kingshighway St.,
Cape Girardeau, MO, 63701, US
4.05 mi from Cape Girardeau, MO, USA
3.54 stars rating. Good. 312 reviews3.54 stars rating. Good. 312 reviews
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Top-Rated hotels

5 hotels in Cape Girardeau

Avg. rating

3.7 (4322 reviews)