Book Boutique Hotels in Mesquite, TX | Choice Hotels

Change your dates to book properties below.

Clarion Inn & Suites DFW North
4770 Plaza Drive,
Irving, TX, 75063, US
26.24 mi from Mesquite, TX, USA
3.85 stars rating. Good. 1426 reviews3.85 stars rating. Good. 1426 reviews
Sold outfor your selected dates
See Availability
Sleep Inn Lancaster Dallas South
3508 N I-35E, Building A,
Lancaster, TX, 75134, US
15.88 mi from Mesquite, TX, USA
3.55 stars rating. Good. 320 reviews3.55 stars rating. Good. 320 reviews
Sold outfor your selected dates
See Availability
EXTENDED STAY
MainStay Suites Lancaster Dallas South
3508 N I-35E, Building B,
Lancaster, TX, 75134, US
15.88 mi from Mesquite, TX, USA
3.3 stars rating. Good. 175 reviews3.3 stars rating. Good. 175 reviews
Sold outfor your selected dates
See Availability
Comfort Suites DFW Airport
4700 W. John Carpenter Fwy.,
Irving, TX, 75063, US
26.12 mi from Mesquite, TX, USA
3.74 stars rating. Good. 2360 reviews3.74 stars rating. Good. 2360 reviews
Sold outfor your selected dates
See Availability
Quality Inn & Suites Richardson-Dallas
2458 N. Central Expressway,
Richardson, TX, 75080, US
16.68 mi from Mesquite, TX, USA
3.02 stars rating. 797 reviews3.02 stars rating. 797 reviews
Sold outfor your selected dates
See Availability
Comfort Suites Lewisville - Dallas
755 E. Vista Ridge Mall Drive,
Lewisville, TX, 75067, US
26.83 mi from Mesquite, TX, USA
3.91 stars rating. Good. 1685 reviews3.91 stars rating. Good. 1685 reviews
Sold outfor your selected dates
See Availability
Comfort Suites Plano - Dallas North
2301 E President George Bush Hwy,
Plano, TX, 75074, US
17.11 mi from Mesquite, TX, USA
3.95 stars rating. Good. 1347 reviews3.95 stars rating. Good. 1347 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites Frisco - Plano
4220 Preston Road,
Frisco, TX, 75034, US
26.79 mi from Mesquite, TX, USA
3.99 stars rating. Good. 1013 reviews3.99 stars rating. Good. 1013 reviews
Sold outfor your selected dates
See Availability
AWARD WINNER
Quality Inn & Suites Plano East - Richardson
1616 N. Central Expressway,
Plano, TX, 75074, US
18.77 mi from Mesquite, TX, USA
4.01 stars rating. Very Good. 996 reviews4.01 stars rating. Very Good. 996 reviews
Sold outfor your selected dates
See Availability
Econo Lodge Inn & Suites Mckinney - Plano North
951 S. Central Expressway,
Mckinney, TX, 75070, US
29.38 mi from Mesquite, TX, USA
3.38 stars rating. Good. 167 reviews3.38 stars rating. Good. 167 reviews
Sold outfor your selected dates
See Availability
Sleep Inn Dallas Love Field-Medical District
1165 Empire Central Place,
Dallas, TX, 75247, US
16.54 mi from Mesquite, TX, USA
4.19 stars rating. Very Good. 881 reviews4.19 stars rating. Very Good. 881 reviews
Sold outfor your selected dates
See Availability
Rodeway Inn Carrollton I-35E
1832 North I - 35 E.,
Carrollton, TX, 75006, US
22.98 mi from Mesquite, TX, USA
3.17 stars rating. Good. 235 reviews3.17 stars rating. Good. 235 reviews
Sold outfor your selected dates
See Availability
Comfort Inn Dallas Park Central
7815-A Lyndon B. Johnson Freew,
Dallas, TX, 75251, US
14.86 mi from Mesquite, TX, USA
3.53 stars rating. Good. 957 reviews3.53 stars rating. Good. 957 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites Dallas Medical-Market Center
1521 Inwood Road,
Dallas, TX, 75247, US
14.9 mi from Mesquite, TX, USA
2.89 stars rating. Fair. 668 reviews2.89 stars rating. Fair. 668 reviews
Sold outfor your selected dates
See Availability
NEW HOTEL
Cambria Hotel Euless - DFW Airport South
751 East Airport Freeway,
Euless, TX, 76039, US
27.83 mi from Mesquite, TX, USA
No Reviews YetNo Reviews Yet
Coming soonStart booking Jan 21, 2026
See Availability
Country Inn & Suites by Radisson, Lewisville, TX
755B E Vista Ridge Mall Dr,
Lewisville, TX, 75067-8340, US
26.82 mi from Mesquite, TX, USA
2.32 stars rating. Fair. 76 reviews2.32 stars rating. Fair. 76 reviews
Sold outfor your selected dates
See Availability
Quality Suites Irving-Las Colinas
1223 Greenway Cir.,
Irving, TX, 75038, US
22.98 mi from Mesquite, TX, USA
3.54 stars rating. Good. 1059 reviews3.54 stars rating. Good. 1059 reviews
Sold outfor your selected dates
See Availability
Quality Inn West Plano - Dallas
5021 West Plano Pkwy,
Plano, TX, 75093, US
20.8 mi from Mesquite, TX, USA
3.87 stars rating. Good. 820 reviews3.87 stars rating. Good. 820 reviews
Sold outfor your selected dates
See Availability
Quality Inn & Suites Dallas-Cityplace
4150 N. Central Expressway,
Dallas, TX, 75204, US
11.53 mi from Mesquite, TX, USA
3.7 stars rating. Good. 312 reviews3.7 stars rating. Good. 312 reviews
Sold outfor your selected dates
See Availability
Sleep Inn Dallas Northwest - Irving
2208 Royal Lane, Building A,
Dallas, TX, 75229, US
19.84 mi from Mesquite, TX, USA
3.83 stars rating. Good. 149 reviews3.83 stars rating. Good. 149 reviews
Sold outfor your selected dates
See Availability
Quality Inn Mesquite - Dallas East
923 Windbell Circle,
Mesquite, TX, 75149, US
1.56 mi from Mesquite, TX, USA
4.03 stars rating. Very Good. 1041 reviews4.03 stars rating. Very Good. 1041 reviews
Sold outfor your selected dates
See Availability
EXTENDED STAY
MainStay Suites Dallas Northwest - Irving
2208 Royal Lane, Building B,
Dallas, TX, 75229, US
19.82 mi from Mesquite, TX, USA
4.08 stars rating. Very Good. 95 reviews4.08 stars rating. Very Good. 95 reviews
Sold outfor your selected dates
See Availability
EXTENDED STAY
MainStay Suites Addison-Dallas
15200 Addison Road,
Addison, TX, 75001, US
18.75 mi from Mesquite, TX, USA
2.09 stars rating. Fair. 162 reviews2.09 stars rating. Fair. 162 reviews
Sold outfor your selected dates
See Availability
Sleep Inn Arlington Near Six Flags
750 Six Flags Dr.,
Arlington, TX, 76011, US
27.17 mi from Mesquite, TX, USA
3.89 stars rating. Good. 3669 reviews3.89 stars rating. Good. 3669 reviews
Sold outfor your selected dates
See Availability
Quality Inn DFW Airport North
8205 Esters Blvd.,
Irving, TX, 75063, US
25.98 mi from Mesquite, TX, USA
3.44 stars rating. Good. 2208 reviews3.44 stars rating. Good. 2208 reviews
Sold outfor your selected dates
See Availability
Comfort Suites The Colony - Plano West
4796 Memorial Drive,
The Colony, TX, 75056, US
26.74 mi from Mesquite, TX, USA
3.53 stars rating. Good. 1320 reviews3.53 stars rating. Good. 1320 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites North Dallas-Addison
13900 Parkside Center Blvd.,
Dallas, TX, 75244, US
18.37 mi from Mesquite, TX, USA
3.27 stars rating. Good. 528 reviews3.27 stars rating. Good. 528 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites Balch Springs - SE Dallas
4019 S. Belt Line Road,
Balch Springs, TX, 75181, US
4.11 mi from Mesquite, TX, USA
4.04 stars rating. Very Good. 299 reviews4.04 stars rating. Very Good. 299 reviews
Sold outfor your selected dates
See Availability
Econo Lodge Inn & Suites Mesquite - Dallas East
317 Highway 80 East,
Mesquite, TX, 75150, US
1.76 mi from Mesquite, TX, USA
2.92 stars rating. Fair. 64 reviews2.92 stars rating. Fair. 64 reviews
Sold outfor your selected dates
See Availability
Comfort Suites West Dallas - Cockrell Hill
4275 DFW Turnpike IH-30,
Dallas, TX, 75211, US
17.18 mi from Mesquite, TX, USA
3.98 stars rating. Good. 1221 reviews3.98 stars rating. Good. 1221 reviews
Sold outfor your selected dates
See Availability
AWARD WINNER
Quality Inn Allen - Plano East
407 Central Expressway South,
Allen, TX, 75013, US
23.39 mi from Mesquite, TX, USA
3.82 stars rating. Good. 698 reviews3.82 stars rating. Good. 698 reviews
Sold outfor your selected dates
See Availability
Quality Inn & Suites I-35 E/Walnut Hill
10835 Composite Drive,
Dallas, TX, 75220, US
18.88 mi from Mesquite, TX, USA
3.23 stars rating. Good. 1140 reviews3.23 stars rating. Good. 1140 reviews
Sold outfor your selected dates
See Availability
Rodeway Inn
3501 East Division Street,
Arlington, TX, 76011, US
26.13 mi from Mesquite, TX, USA
2.29 stars rating. Fair. 420 reviews2.29 stars rating. Fair. 420 reviews
Sold outfor your selected dates
See Availability
Comfort Suites Waxahachie - Dallas
131 RVG Plaza,
Waxahachie, TX, 75165, US
27.78 mi from Mesquite, TX, USA
4 stars rating. Very Good. 1720 reviews4 stars rating. Very Good. 1720 reviews
Sold outfor your selected dates
See Availability
Quality Inn & Suites Terrell
103 Mira Place,
Terrell, TX, 75160, US
19.14 mi from Mesquite, TX, USA
3.86 stars rating. Good. 661 reviews3.86 stars rating. Good. 661 reviews
Sold outfor your selected dates
See Availability
Comfort Suites NW Dallas Near Love Field
2287 W. Northwest Highway,
Dallas, TX, 75220, US
18.22 mi from Mesquite, TX, USA
3.54 stars rating. Good. 1136 reviews3.54 stars rating. Good. 1136 reviews
Sold outfor your selected dates
See Availability
Clarion Hotel The Colony - Plano West
4301 Paige Rd,
The Colony, TX, 75056, US
26.7 mi from Mesquite, TX, USA
3.76 stars rating. Good. 171 reviews3.76 stars rating. Good. 171 reviews
Sold outfor your selected dates
See Availability
Comfort Suites North Dallas
13165 North Central Expressway,
Dallas, TX, 75243, US
14.62 mi from Mesquite, TX, USA
1.96 stars rating. Fair. 27 reviews1.96 stars rating. Fair. 27 reviews
Sold outfor your selected dates
See Availability
NEW TO CHOICE
Comfort Suites Plano East - Richardson
640 E Park Blvd,
Plano, TX, 75074-5430, US
19.12 mi from Mesquite, TX, USA
No Reviews YetNo Reviews Yet
Coming soonStart booking Jan 05, 2026
See Availability
Cambria Hotel Richardson - Dallas
3605 Shire Blvd.,
Richardson, TX, 75082, US
17.03 mi from Mesquite, TX, USA
4.17 stars rating. Very Good. 1008 reviews4.17 stars rating. Very Good. 1008 reviews
Sold outfor your selected dates
See Availability
AWARD WINNER
Quality Inn Ennis
107 Chamber of Commerce Dr.,
Ennis, TX, 75119, US
29.88 mi from Mesquite, TX, USA
4.7 stars rating. Exceptional. 745 reviews4.7 stars rating. Exceptional. 745 reviews
Sold outfor your selected dates
See Availability
Comfort Suites Grand Prairie - Arlington North
702 Paddock Way Drive,
Grand Prairie, TX, 75050, US
26.66 mi from Mesquite, TX, USA
4.12 stars rating. Very Good. 976 reviews4.12 stars rating. Very Good. 976 reviews
Sold outfor your selected dates
See Availability
Cambria Hotel Plano Frisco
7500 Parkwood Blvd.,
Plano, TX, 75024, US
25.14 mi from Mesquite, TX, USA
4.44 stars rating. Excellent. 2404 reviews4.44 stars rating. Excellent. 2404 reviews
Sold outfor your selected dates
See Availability
Comfort Suites DeSoto Dallas South
1211 E. Wintergreen Rd.,
Desoto, TX, 75115, US
16.64 mi from Mesquite, TX, USA
3.74 stars rating. Good. 652 reviews3.74 stars rating. Good. 652 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites Red Oak - Dallas Area
404 North I-35 East,
Red Oak, TX, 75154, US
20.93 mi from Mesquite, TX, USA
3.32 stars rating. Good. 851 reviews3.32 stars rating. Good. 851 reviews
Sold outfor your selected dates
See Availability
Quality Suites Addison-Dallas
4555 Beltline Road,
Addison, TX, 75001, US
18.93 mi from Mesquite, TX, USA
3.11 stars rating. Good. 1724 reviews3.11 stars rating. Good. 1724 reviews
Sold outfor your selected dates
See Availability
NEW TO CHOICE
Rodeway Inn Garland Harbor Point
825 E Interstate 30,
Garland, TX, 75043, US
6.51 mi from Mesquite, TX, USA
No Reviews YetNo Reviews Yet
Sold outfor your selected dates
See Availability
Comfort Inn Dallas North Love Field Airport
11069 Composite Drive,
Dallas, TX, 75229, US
19.03 mi from Mesquite, TX, USA
2.18 stars rating. Fair. 165 reviews2.18 stars rating. Fair. 165 reviews
Sold outfor your selected dates
See Availability
Comfort Suites DFW N/Grapevine
1805 Enchanted Way,
Grapevine, TX, 76051, US
28.59 mi from Mesquite, TX, USA
3.93 stars rating. Good. 1739 reviews3.93 stars rating. Good. 1739 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites Love Field-Dallas Market Center
7138 N. Stemmons Fwy,
Dallas, TX, 75247, US
15.98 mi from Mesquite, TX, USA
3.51 stars rating. Good. 1692 reviews3.51 stars rating. Good. 1692 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites Wylie
2011 N. Highway 78,
Wylie, TX, 75098, US
18.34 mi from Mesquite, TX, USA
3.18 stars rating. Good. 218 reviews3.18 stars rating. Good. 218 reviews
Sold outfor your selected dates
See Availability
Quality Inn & Suites Grand Prairie South
3891 S. Great Southwest Pkwy,
Grand Prairie, TX, 75052, US
26.52 mi from Mesquite, TX, USA
4.08 stars rating. Very Good. 520 reviews4.08 stars rating. Very Good. 520 reviews
Sold outfor your selected dates
See Availability
Country Inn & Suites by Radisson, DFW Airport South, TX
2000 Hard Rock Road,
Irving, TX, 75061, US
24.49 mi from Mesquite, TX, USA
2.71 stars rating. Fair. 191 reviews2.71 stars rating. Fair. 191 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites Cedar Hill Duncanville
1419 N. US Highway 67,
Cedar Hill, TX, 75104, US
21.25 mi from Mesquite, TX, USA
3.69 stars rating. Good. 495 reviews3.69 stars rating. Good. 495 reviews
Sold outfor your selected dates
See Availability
Comfort Suites Arlington - Entertainment District
411 W. Road to Six Flags,
Arlington, TX, 76011, US
29.68 mi from Mesquite, TX, USA
4.2 stars rating. Excellent. 2581 reviews4.2 stars rating. Excellent. 2581 reviews
Sold outfor your selected dates
See Availability
NEW TO CHOICE
Sleep Inn
1439 N Hwy 67,
Cedar Hill, TX, 75104, US
21.13 mi from Mesquite, TX, USA
3.93 stars rating. Good. 15 reviews3.93 stars rating. Good. 15 reviews
Sold outfor your selected dates
See Availability
Quality Inn & Suites Garland - East Dallas
1635 E I30,
Garland, TX, 75043, US
7.57 mi from Mesquite, TX, USA
3.68 stars rating. Good. 499 reviews3.68 stars rating. Good. 499 reviews
Sold outfor your selected dates
See Availability
Comfort Inn Plano-Dallas
4901 Old Shepard Place,
Plano, TX, 75093, US
20.93 mi from Mesquite, TX, USA
2.76 stars rating. Fair. 256 reviews2.76 stars rating. Fair. 256 reviews
Sold outfor your selected dates
See Availability
Quality Inn & Suites North Mesquite I-30
3424 Sorrento Dr,
Mesquite, TX, 75150-2510, US
4.29 mi from Mesquite, TX, USA
3.91 stars rating. Good. 122 reviews3.91 stars rating. Good. 122 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites Irving Las Colinas DFW
850 W. Walnut Hill Lane,
Irving, TX, 75038, US
22.41 mi from Mesquite, TX, USA
3.86 stars rating. Good. 186 reviews3.86 stars rating. Good. 186 reviews
Sold outfor your selected dates
See Availability
Rodeway Inn & Suites Lewisville I-35
881 S. Stemmons Freeway,
Lewisville, TX, 75067, US
29.93 mi from Mesquite, TX, USA
2.43 stars rating. Fair. 464 reviews2.43 stars rating. Fair. 464 reviews
Sold outfor your selected dates
See Availability
NEW TO CHOICE
Comfort Inn & Suites Frisco East - McKinney
14700 TX-121,
Frisco, TX, 75035, US
26.02 mi from Mesquite, TX, USA
4.24 stars rating. Excellent. 96 reviews4.24 stars rating. Excellent. 96 reviews
Sold outfor your selected dates
See Availability
Quality Inn & Suites Irving DFW Airport South
4940 W Airport Freeway,
Irving, TX, 75062, US
25.08 mi from Mesquite, TX, USA
3.71 stars rating. Good. 1439 reviews3.71 stars rating. Good. 1439 reviews
Sold outfor your selected dates
See Availability
NEW TO CHOICE
Landmark Hotel Dallas - Addison
14975 Landmark Blvd,
Dallas, TX, 75254-6709, US
18.52 mi from Mesquite, TX, USA
No Reviews YetNo Reviews Yet
Coming soonStart booking Dec 13, 2025
See Availability

Other Mesquite searches

All Hotels in Mesquite

Hotel Deals in Mesquite

Extended Stay Hotels in Mesquite

Pet Friendly Hotels in Mesquite

Top Rated Hotels in Mesquite

Good to know

Boutique hotels

64 hotels in Mesquite

Avg. rating

3.3 (51061 reviews)