Book Top Rated Hotels in Santa Fe, TX

Comfort Inn & Suites Texas City I-45
10700 Emmett F. Lowry Expwy,
Texas City, TX, 77591, US
4.99 mi from Santa Fe, TX, USA
2.12 stars rating. Fair. 41 reviews2.12 stars rating. Fair. 41 reviews
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Strikethrough Rate:~~$76~~Discounted rate:$71USD/night
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Quality Inn Texas City I-45
2320 FM 2004,
Texas City, TX, 77591, US
5.01 mi from Santa Fe, TX, USA
3.5 stars rating. Good. 472 reviews3.5 stars rating. Good. 472 reviews
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Strikethrough Rate:~~$72~~Discounted rate:$68USD/night
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EXTENDED STAY
MainStay Suites Houston NASA/Clear Lake
1050 Bay Area Blvd,
Houston, TX, 77058, US
12.26 mi from Santa Fe, TX, USA
3.48 stars rating. Good. 101 reviews3.48 stars rating. Good. 101 reviews
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Strikethrough Rate:~~$79~~Discounted rate:$74USD/night
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Comfort Suites Seabrook - Kemah
5755 Bayport Blvd,
Seabrook, TX, 77586, US
15.44 mi from Santa Fe, TX, USA
3.25 stars rating. Good. 267 reviews3.25 stars rating. Good. 267 reviews
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Strikethrough Rate:~~$79~~Discounted rate:$54USD/night
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Stay Longer. Save More.
Say hello to WoodSpring Suites® hotels! Designed for longer stays, we offer contemporary suites with in-room kitchens and free WiFi. Plus, our affordable rates cost less per night when you stay a week, month or more.
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Comfort Suites near NASA - Clear Lake
16931 N. Texas Ave,
Webster, TX, 77598, US
11.46 mi from Santa Fe, TX, USA
3.88 stars rating. Good. 1156 reviews3.88 stars rating. Good. 1156 reviews
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Strikethrough Rate:~~$82~~Discounted rate:$67USD/night
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AWARD WINNER
Quality Inn & Suites Seabrook- NASA- Kemah
2720 Nasa Parkway,
Seabrook, TX, 77586, US
13.23 mi from Santa Fe, TX, USA
4.4 stars rating. Excellent. 1224 reviews4.4 stars rating. Excellent. 1224 reviews
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Strikethrough Rate:~~$89~~Discounted rate:$80USD/night
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EXTENDED STAY
MainStay Suites Texas Medical Center/Reliant Park
3134 Old Spanish Trail,
Houston, TX, 77054, US
27.59 mi from Santa Fe, TX, USA
3.96 stars rating. Good. 2362 reviews3.96 stars rating. Good. 2362 reviews
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Strikethrough Rate:~~$79~~Discounted rate:$59USD/night
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Econo Lodge Galveston Seawall
3008 Seawall Blvd,
Galveston, TX, 77550-7677, US
19.79 mi from Santa Fe, TX, USA
2.74 stars rating. Fair. 121 reviews2.74 stars rating. Fair. 121 reviews
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Strikethrough Rate:~~$73~~Discounted rate:$51USD/night
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Quality Inn Houston East I-10
828 Mercury Drive,
Houston, TX, 77013, US
28.67 mi from Santa Fe, TX, USA
2.97 stars rating. Fair. 454 reviews2.97 stars rating. Fair. 454 reviews
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Strikethrough Rate:~~$58~~Discounted rate:$55USD/night
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Quality Inn & Suites Galveston - Beachfront
5924 Seawall Blvd.,
Galveston, TX, 77551, US
18.59 mi from Santa Fe, TX, USA
4.04 stars rating. Very Good. 3190 reviews4.04 stars rating. Very Good. 3190 reviews
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Strikethrough Rate:~~$87~~Discounted rate:$63USD/night
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FULLY RENOVATED
Clarion Pointe Galveston - Beachfront
5914 Seawall Blvd,
Galveston, TX, 77551, US
18.62 mi from Santa Fe, TX, USA
3.89 stars rating. Good. 9 reviews3.89 stars rating. Good. 9 reviews
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Strikethrough Rate:~~$84~~Discounted rate:$60USD/night
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Econo Lodge Inn & Suites Channelview - Houston East
16007 East Fwy,
Channelview, TX, 77530, US
27.79 mi from Santa Fe, TX, USA
3.47 stars rating. Good. 17 reviews3.47 stars rating. Good. 17 reviews
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Strikethrough Rate:~~$59~~Discounted rate:$55USD/night
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Sleep Inn & Suites Galveston Island
6628 Broadway Street,
Galveston, TX, 77554, US
16.78 mi from Santa Fe, TX, USA
2.95 stars rating. Fair. 859 reviews2.95 stars rating. Fair. 859 reviews
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Strikethrough Rate:~~$75~~Discounted rate:$71USD/night
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Rodeway Inn South Houston
2042 Houston Blvd.,
South Houston, TX, 77587, US
20.45 mi from Santa Fe, TX, USA
2.97 stars rating. Fair. 118 reviews2.97 stars rating. Fair. 118 reviews
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Strikethrough Rate:~~$63~~Discounted rate:$59USD/night
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Quality Suites Houston Hobby Airport
7775 Airport Blvd,
Houston, TX, 77061, US
21.99 mi from Santa Fe, TX, USA
3.95 stars rating. Good. 220 reviews3.95 stars rating. Good. 220 reviews
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Strikethrough Rate:~~$73~~Discounted rate:$59USD/night
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Comfort Suites Channelview - Houston East
15813 2nd Street,
Channelview, TX, 77530, US
27.72 mi from Santa Fe, TX, USA
3.3 stars rating. Good. 299 reviews3.3 stars rating. Good. 299 reviews
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Strikethrough Rate:~~$67~~Discounted rate:$63USD/night
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Econo Lodge Inn & Suites East Houston I-10
1016 Maxey Road,
Houston, TX, 77015, US
27.96 mi from Santa Fe, TX, USA
4.04 stars rating. Very Good. 387 reviews4.04 stars rating. Very Good. 387 reviews
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Strikethrough Rate:~~$70~~Discounted rate:$63USD/night
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Quality Inn Pasadena - Houston East
114 S. Richey St.,
Pasadena, TX, 77506, US
23.99 mi from Santa Fe, TX, USA
3.82 stars rating. Good. 314 reviews3.82 stars rating. Good. 314 reviews
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Strikethrough Rate:~~$80~~Discounted rate:$56USD/night
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Comfort Suites Deer Park Pasadena
1501 Center St.,
Deer Park, TX, 77536, US
22.08 mi from Santa Fe, TX, USA
3.95 stars rating. Good. 578 reviews3.95 stars rating. Good. 578 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$67USD/night
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Comfort Suites Galveston Cruise Port Area - Beachside
3606 89th Street,
Galveston, TX, 77554, US
17.54 mi from Santa Fe, TX, USA
3.47 stars rating. Good. 1689 reviews3.47 stars rating. Good. 1689 reviews
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Strikethrough Rate:~~$122~~Discounted rate:$93USD/night
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Comfort Suites La Porte - Baytown
902 South 8th Street,
La Porte, TX, 77571, US
19.61 mi from Santa Fe, TX, USA
4.21 stars rating. Excellent. 684 reviews4.21 stars rating. Excellent. 684 reviews
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Strikethrough Rate:~~$108~~Discounted rate:$83USD/night
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Quality Inn & Suites NRG Park - Medical Center
2364 South Loop West,
Houston, TX, 77054, US
27.85 mi from Santa Fe, TX, USA
3.02 stars rating. 1472 reviews3.02 stars rating. 1472 reviews
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Strikethrough Rate:~~$72~~Discounted rate:$65USD/night
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Sleep Inn & Suites Pearland - Houston South
1908 Country Place Parkway,
Pearland, TX, 77584, US
21.64 mi from Santa Fe, TX, USA
3.96 stars rating. Good. 659 reviews3.96 stars rating. Good. 659 reviews
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Strikethrough Rate:~~$86~~Discounted rate:$78USD/night
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Comfort Suites Houston near Medical Center- NRG Stadium
1055 McNee Road, East of Main Street,
Houston, TX, 77054, US
28.48 mi from Santa Fe, TX, USA
4.32 stars rating. Excellent. 1795 reviews4.32 stars rating. Excellent. 1795 reviews
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Strikethrough Rate:~~$112~~Discounted rate:$105USD/night
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Comfort Inn & Suites Galveston Central Island near Pier
2818 Avenue R 1 2,
Galveston, TX, 77550, US
19.84 mi from Santa Fe, TX, USA
3.28 stars rating. Good. 239 reviews3.28 stars rating. Good. 239 reviews
$99USD/night
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Seabreeze Hotel, an Ascend Collection Hotel
2311 Avenue P 1 2,
Galveston, TX, 77550, US
20.02 mi from Santa Fe, TX, USA
4.48 stars rating. Excellent. 60 reviews4.48 stars rating. Excellent. 60 reviews
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Good to know

Top-Rated hotels

26 hotels in Santa Fe

Highest Price

$105

Lowest Price

$51

Avg. rating

25 Top Rated hotels near Santa Fe, TX, USA

Comfort Inn & Suites Texas City I-45

Quality Inn Texas City I-45

MainStay Suites Houston NASA/Clear Lake

Comfort Suites Seabrook - Kemah

Stay Longer. Save More.

Comfort Suites near NASA - Clear Lake

Quality Inn & Suites Seabrook- NASA- Kemah

MainStay Suites Texas Medical Center/Reliant Park

Econo Lodge Galveston Seawall

Quality Inn Houston East I-10

Quality Inn & Suites Galveston - Beachfront

Clarion Pointe Galveston - Beachfront

Econo Lodge Inn & Suites Channelview - Houston East

Sleep Inn & Suites Galveston Island

Rodeway Inn South Houston

Quality Suites Houston Hobby Airport

Comfort Suites Channelview - Houston East

Econo Lodge Inn & Suites East Houston I-10

Quality Inn Pasadena - Houston East

Comfort Suites Deer Park Pasadena

Comfort Suites Galveston Cruise Port Area - Beachside

Comfort Suites La Porte - Baytown

Quality Inn & Suites NRG Park - Medical Center

Sleep Inn & Suites Pearland - Houston South

Comfort Suites Houston near Medical Center- NRG Stadium

Comfort Inn & Suites Galveston Central Island near Pier

Change your dates to book properties below.

Seabreeze Hotel, an Ascend Collection Hotel

Other Santa Fe searches

Good to know

26 hotels in Santa Fe

$105

$51

3.6 (18787 reviews)