Book Boutique Hotels in Clayton, MO

AWARD WINNER
Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
10.51 km from Clayton, MO, US
4.73 stars rating. Exceptional. 2065 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$111USD/night
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MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
0.02 km from Clayton, MO, US
3.14 stars rating. Good. 212 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$101USD/night
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Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
12.86 km from Clayton, MO, US
4.06 stars rating. Very Good. 192 reviews
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Strikethrough Rate:~~$139~~Discounted rate:$113USD/night
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Comfort Inn & Suites Hazelwood - St. Louis
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
16.25 km from Clayton, MO, US
4.1 stars rating. Very Good. 2008 reviews
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Strikethrough Rate:~~$107~~Discounted rate:$100USD/night
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Quality Inn Saint Louis Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
11.42 km from Clayton, MO, US
3.26 stars rating. Good. 3081 reviews
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Strikethrough Rate:~~$86~~Discounted rate:$80USD/night
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Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
15.86 km from Clayton, MO, US
3.41 stars rating. Good. 1482 reviews
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Strikethrough Rate:~~$83~~Discounted rate:$77USD/night
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River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
13.31 km from Clayton, MO, US
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Strikethrough Rate:~~$135~~Discounted rate:$117USD/night
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Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
17.8 km from Clayton, MO, US
3.52 stars rating. Good. 1360 reviews
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Strikethrough Rate:~~$89~~Discounted rate:$74USD/night
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Comfort Inn & Suites Saint Louis Lafayette Square
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
10.71 km from Clayton, MO, US
3.79 stars rating. Good. 127 reviews
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Strikethrough Rate:~~$189~~Discounted rate:$176USD/night
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MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
12.9 km from Clayton, MO, US
3.92 stars rating. Good. 244 reviews
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Strikethrough Rate:~~$133~~Discounted rate:$108USD/night
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Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
19.81 km from Clayton, MO, US
4.02 stars rating. Very Good. 2113 reviews
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Strikethrough Rate:~~$139~~Discounted rate:$132USD/night
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Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
18.02 km from Clayton, MO, US
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Strikethrough Rate:~~$125~~Discounted rate:$109USD/night
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NEW TO CHOICE
Radisson Hotel St. Louis Downtown Convention Center
811 N 9th St,
St. Louis, MO, 63101, US
13.13 km from Clayton, MO, US
1.43 stars rating. Fair. 122 reviews
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Strikethrough Rate:~~$249~~Discounted rate:$237USD/night
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AWARD WINNER
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
19.76 km from Clayton, MO, US
4.64 stars rating. Exceptional. 688 reviews
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Strikethrough Rate:~~$264~~Discounted rate:$246USD/night
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Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
25.97 km from Clayton, MO, US
4.05 stars rating. Very Good. 237 reviews
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Strikethrough Rate:~~$115~~Discounted rate:$107USD/night
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Econo Lodge Inn & Suites Granite City - St. Louis
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
23.98 km from Clayton, MO, US
3.46 stars rating. Good. 396 reviews
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Strikethrough Rate:~~$74~~Discounted rate:$69USD/night
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Comfort Inn Edwardsville - St. Louis
3080 S. SR 157,
Edwardsville, IL, 62025, US
32.83 km from Clayton, MO, US
4.16 stars rating. Very Good. 1387 reviews
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Strikethrough Rate:~~$125~~Discounted rate:$113USD/night
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Sleep Inn Saint Charles North
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
26.35 km from Clayton, MO, US
3.08 stars rating. Fair. 1050 reviews
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Strikethrough Rate:~~$95~~Discounted rate:$89USD/night
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Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
27.17 km from Clayton, MO, US
3.89 stars rating. Good. 2522 reviews
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Strikethrough Rate:~~$135~~Discounted rate:$122USD/night
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Comfort Inn Collinsville near St. Louis
8 Commerce Dr.,
Collinsville, IL, 62234, US
29.19 km from Clayton, MO, US
4.2 stars rating. Excellent. 1983 reviews
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Strikethrough Rate:~~$161~~Discounted rate:$145USD/night
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Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
35.13 km from Clayton, MO, US
3.64 stars rating. Good. 868 reviews
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Strikethrough Rate:~~$94~~Discounted rate:$85USD/night
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Comfort Suites Fairview Heights - St Louis
137 Ludwig Drive,
Fairview Heights, IL, 62208, US
30.55 km from Clayton, MO, US
3.45 stars rating. Good. 1821 reviews
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Strikethrough Rate:~~$89~~Discounted rate:$80USD/night
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Quality Inn O'Fallon IL - St. Louis
1409 W US 50,
O Fallon, IL, 62269, US
34.26 km from Clayton, MO, US
3.54 stars rating. Good. 958 reviews
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Strikethrough Rate:~~$79~~Discounted rate:$71USD/night
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Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
32.86 km from Clayton, MO, US
4.23 stars rating. Excellent. 1283 reviews
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Strikethrough Rate:~~$153~~Discounted rate:$124USD/night
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Quality Inn & Suites Caseyville - St. Louis
2180 Patricia Dr.,
Caseyville, IL, 62232, US
25.9 km from Clayton, MO, US
2.7 stars rating. Fair. 723 reviews
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Strikethrough Rate:~~$89~~Discounted rate:$83USD/night
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Econo Lodge Inn & Suites Fairview Heights - St. Louis
305 Salem Place,
Fairview Heights, IL, 62208, US
31.45 km from Clayton, MO, US
3.77 stars rating. Good. 328 reviews
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Strikethrough Rate:~~$75~~Discounted rate:$66USD/night
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Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive,
Fairview Heights, IL, 62208, US
30.57 km from Clayton, MO, US
3.16 stars rating. Good. 243 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$98USD/night
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Sleep Inn O'Fallon near I-64
140 Venita Drive,
O Fallon, IL, 62269, US
35.46 km from Clayton, MO, US
3.36 stars rating. Good. 1359 reviews
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Strikethrough Rate:~~$76~~Discounted rate:$71USD/night
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Quality Inn Pacific near Six Flags St. Louis
1400 West Osage St.,
Pacific, MO, 63069, US
39.62 km from Clayton, MO, US
4.01 stars rating. Very Good. 669 reviews
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Strikethrough Rate:~~$124~~Discounted rate:$112USD/night
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Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy,
Fairview Heights, IL, 62208, US
31.51 km from Clayton, MO, US
3.52 stars rating. Good. 227 reviews
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Strikethrough Rate:~~$139~~Discounted rate:$132USD/night
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Comfort Inn & Suites St. Louis-O'Fallon
8170 Veterans Memorial Pkwy,
O Fallon, MO, 63366, US
34.52 km from Clayton, MO, US
3.67 stars rating. Good. 1933 reviews
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Strikethrough Rate:~~$140~~Discounted rate:$130USD/night
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Comfort Inn Near Six Flags St. Louis
1320 Thornton St.,
Pacific, MO, 63069, US
39.49 km from Clayton, MO, US
4.06 stars rating. Very Good. 1786 reviews
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Strikethrough Rate:~~$150~~Discounted rate:$135USD/night
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The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
35.25 km from Clayton, MO, US
2.91 stars rating. Fair. 114 reviews
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Strikethrough Rate:~~$149~~Discounted rate:$142USD/night
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Comfort Inn & Suites OFallon - St Louis Area
116 Regency Park,
O'Fallon, IL, 62269, US
35.43 km from Clayton, MO, US
2.35 stars rating. Fair. 129 reviews
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Strikethrough Rate:~~$84~~Discounted rate:$76USD/night
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34 hotels in Clayton

Highest Price

$246

Lowest Price

$66

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34 Boutique hotels near Clayton, MO, US

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Clayton hotels by brand

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34 hotels in Clayton

$246

$66

3.6 (33710 reviews)