Extended Stay Hotels in Defiance, MO

MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
35.12 km from Defiance, MO, US
3.91 stars rating. Good. 240 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$91USD/night
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MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
37.77 km from Defiance, MO, US
3.22 stars rating. Good. 195 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$101USD/night
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Below are additional hotels in the area that do not match your exact search criteria.

Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
11.83 km from Defiance, MO, US
3.91 stars rating. Good. 2484 reviews
Book Now & Save 18%
Strikethrough Rate:~~$99~~Discounted rate:$80USD/night
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Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
11.25 km from Defiance, MO, US
4.23 stars rating. Excellent. 1258 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$93USD/night
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Comfort Inn & Suites St. Louis-O'Fallon
8170 Veterans Memorial Pkwy,
O Fallon, MO, 63366, US
20.55 km from Defiance, MO, US
3.68 stars rating. Good. 1907 reviews
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Strikethrough Rate:~~$103~~Discounted rate:$96USD/night
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Quality Inn Pacific near Six Flags St. Louis
1400 West Osage St.,
Pacific, MO, 63069, US
16.61 km from Defiance, MO, US
4 stars rating. Very Good. 657 reviews
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Strikethrough Rate:~~$94~~Discounted rate:$85USD/night
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Comfort Inn Near Six Flags St. Louis
1320 Thornton St.,
Pacific, MO, 63069, US
16.41 km from Defiance, MO, US
4.06 stars rating. Very Good. 1766 reviews
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Strikethrough Rate:~~$120~~Discounted rate:$112USD/night
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Quality Inn Foristell
12 Highway W,
Foristell, MO, 63348, US
25.61 km from Defiance, MO, US
4.21 stars rating. Excellent. 926 reviews
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Strikethrough Rate:~~$105~~Discounted rate:$85USD/night
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Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
29.13 km from Defiance, MO, US
4.02 stars rating. Very Good. 2079 reviews
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Strikethrough Rate:~~$94~~Discounted rate:$87USD/night
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Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
25.76 km from Defiance, MO, US
4.07 stars rating. Very Good. 225 reviews
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Strikethrough Rate:~~$108~~Discounted rate:$100USD/night
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AWARD WINNER
Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
33.56 km from Defiance, MO, US
4.73 stars rating. Exceptional. 1959 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$111USD/night
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Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
35.11 km from Defiance, MO, US
4.05 stars rating. Very Good. 183 reviews
Book Now & Save 16%
Strikethrough Rate:~~$88~~Discounted rate:$74USD/night
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AWARD WINNER
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
29.78 km from Defiance, MO, US
4.64 stars rating. Exceptional. 650 reviews
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Strikethrough Rate:~~$151~~Discounted rate:$140USD/night
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Comfort Inn & Suites Hazelwood - St. Louis
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
40.14 km from Defiance, MO, US
4.11 stars rating. Very Good. 1990 reviews
Book Now & Save 12%
Strikethrough Rate:~~$85~~Discounted rate:$75USD/night
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Quality Inn Saint Louis Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
38.28 km from Defiance, MO, US
3.27 stars rating. Good. 3055 reviews
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Strikethrough Rate:~~$62~~Discounted rate:$57USD/night
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Sleep Inn Saint Charles North
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
31.12 km from Defiance, MO, US
3.09 stars rating. Fair. 1040 reviews
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Strikethrough Rate:~~$87~~Discounted rate:$81USD/night
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Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
41.6 km from Defiance, MO, US
3.41 stars rating. Good. 1467 reviews
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Strikethrough Rate:~~$69~~Discounted rate:$64USD/night
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River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
46.14 km from Defiance, MO, US
No Reviews Yet
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Strikethrough Rate:~~$135~~Discounted rate:$111USD/night
Special Rate
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Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd.,
Saint Louis, MO, 63146, US
29.95 km from Defiance, MO, US
3.55 stars rating. Good. 3113 reviews
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Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
29.04 km from Defiance, MO, US
No Reviews Yet
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Good to know

Extended stay hotels

2 of 20 hotels in Defiance

Highest Price

$140

Lowest Price

$57

Avg. rating

3.5 (25194 reviews)

Weekly Rate

$399

Monthly Rate

18 Extended Stay hotels near Defiance, MO, US

MainStay Suites St. Louis Airport

MainStay Suites St. Louis - Galleria

Below are additional hotels in the area that do not match your exact search criteria.

Comfort Inn & Suites Chesterfield - St. Louis

Sleep Inn & Suites O'Fallon MO - Technology Drive

Comfort Inn & Suites St. Louis-O'Fallon

Quality Inn Pacific near Six Flags St. Louis

Comfort Inn Near Six Flags St. Louis

Quality Inn Foristell

Comfort Suites St Charles-St Louis

Country Inn & Suites by Radisson, St. Peters, MO

Comfort Suites St. Louis - Sunset Hills

Comfort Inn St. Louis Airport

Country Inn & Suites by Radisson, St. Charles Historic District

Comfort Inn & Suites Hazelwood - St. Louis

Quality Inn Saint Louis Airport

Sleep Inn Saint Charles North

Quality Inn Florissant-St. Louis

River City Casino & Hotel

Change your dates to book properties below.

Comfort Inn St. Louis - Westport Event Center

Hollywood Casino St Louis

Other Defiance searches

Good to know

2 of 20 hotels in Defiance

$140

$57

3.5 (25194 reviews)

$399

$1,710