The Bradford Hotel, an Ascend Collection Hotel
1260 E. Independence St.,Springfield, MO, 65804-4284, US0.81 km from Sleep Inn Springfield South I60 near Medical District, Springfield, MO, USSee AvailabilityStrikethrough Rate:$142Discounted rate:$127USD/nightMember Rate
Comfort Inn South - Springfield
3776 S Glenstone Avenue,Springfield, MO, 65804, US2.28 km from Sleep Inn Springfield South I60 near Medical District, Springfield, MO, USSee AvailabilityStrikethrough Rate:$159Discounted rate:$143USD/nightMember Rate
Quality Inn & Suites Chesterfield Village
3930 South Overland,Springfield, MO, 65807, US4.13 km from Sleep Inn Springfield South I60 near Medical District, Springfield, MO, USSee AvailabilityStrikethrough Rate:$130Discounted rate:$117USD/nightMember Rate
Quality Inn US65 & E Battlefield Rd Springfield
3330 E. Battlefield Rd.,Springfield, MO, 65804, US5.04 km from Sleep Inn Springfield South I60 near Medical District, Springfield, MO, USSee AvailabilityStrikethrough Rate:$121Discounted rate:$115USD/nightMember Rate
MainStay Suites Springfield South - Battlefield Rd
1550 E Raynell Pl.,Springfield, MO, 65804, US2.56 km from Sleep Inn Springfield South I60 near Medical District, Springfield, MO, USSee AvailabilityStrikethrough Rate:$189Discounted rate:$183USD/nightMember Rate
Comfort Inn & Suites Springfield I-44
2815 North Glenstone Ave,Springfield, MO, 65803, US12.46 km from Sleep Inn Springfield South I60 near Medical District, Springfield, MO, USSee AvailabilityStrikethrough Rate:$179Discounted rate:$161USD/nightMember RateOasis Hotel & Conv. Center, an Ascend Collection Hotel
2546 North Glenstone,Springfield, MO, 65803, US12.07 km from Sleep Inn Springfield South I60 near Medical District, Springfield, MO, USSee AvailabilityStrikethrough Rate:$189Discounted rate:$170USD/nightMember RateQuality Inn Ozark-Springfield South
1900 West Evangel Street,Ozark, MO, 65721, US13.43 km from Sleep Inn Springfield South I60 near Medical District, Springfield, MO, USSee AvailabilityStrikethrough Rate:$129Discounted rate:$123USD/nightMember Rate
Econo Lodge Springfield I-44
2611 N. Glenstone Ave.,Springfield, MO, 65803, US12.09 km from Sleep Inn Springfield South I60 near Medical District, Springfield, MO, USSee AvailabilityStrikethrough Rate:$110Discounted rate:$104USD/nightMember Rate
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Quality Inn & Suites Mount Vernon
1125 E. Daniel Dr.,Mount Vernon, MO, 65712, US46.96 km from Sleep Inn Springfield South I60 near Medical District, Springfield, MO, USSee AvailabilitySold outfor your selected dates
Clarion Pointe Springfield Southeast
3034 S Moulder Ave,Springfield, MO, 65804, US4.91 km from Sleep Inn Springfield South I60 near Medical District, Springfield, MO, USSee AvailabilityComing soonStart booking May 01, 2026
Country Inn & Suites by Radisson, Springfield Downtown
1117 E St Louis St,Springfield, MO, 65806-2527, US8.17 km from Sleep Inn Springfield South I60 near Medical District, Springfield, MO, USSee AvailabilityComing soonStart booking Jun 27, 2026
Sleep Inn Springfield South I60 near Medical District
233 E Camino Alto,Springfield, MO, 65810, US1.62 km from Sleep Inn Springfield South I60 near Medical District, Springfield, MO, USSee AvailabilitySold outfor your selected dates
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Springfield hotels by brand
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Number of hotels
9 of 13 hotels in Springfield
Highest Price
$183
Lowest Price
$104
Avg. rating