Comfort Inn & Suites Sikeston I-55

Whether you’re traveling for business or a vacationing tourist, alone or with your kids, you'll find everything you need to keep you on top of your game during your stay at our pet-friendly Comfort Inn & Suites^® Sikeston hotel. Each of our spacious guest rooms offer what you need to feel at home, including premium bedding, linens and pillows, microwave and refrigerator, coffee maker, flat-screen TV, and full bathroom. Many rooms also offer a sofa bed.