Book Top Rated Hotels in Seneca, MO | Choice Hotels

Sleep Inn South Joplin
4100 Missouri 43,
Joplin, MO, 64804, US
19.1 km from Seneca, MO
4.33 stars rating. Excellent. 960 reviews4.33 stars rating. Excellent. 960 reviews
Book Now & Save 10%
Strikethrough Rate:~~$122~~Discounted rate:$110USD/night
Member Rate
See Availability
Quality Inn Joplin I-44
3325 Arizona Avenue,
Joplin, MO, 64804, US
26.13 km from Seneca, MO
4.04 stars rating. Very Good. 1157 reviews4.04 stars rating. Very Good. 1157 reviews
$110USD/night
See Availability
Econo Lodge Inn & Suites Joplin
3510 South Range Line Rd,
Joplin, MO, 64804, US
25.93 km from Seneca, MO
3.22 stars rating. Good. 999 reviews3.22 stars rating. Good. 999 reviews
Book Now & Save 10%
Strikethrough Rate:~~$79~~Discounted rate:$71USD/night
Member Rate
See Availability
Econo Lodge Anderson
491 E Highway 76,
Anderson, MO, 64831, US
27.18 km from Seneca, MO
3.7 stars rating. Good. 379 reviews3.7 stars rating. Good. 379 reviews
Book Now & Save 10%
Strikethrough Rate:~~$82~~Discounted rate:$74USD/night
Member Rate
See Availability
Sleep Inn & Suites Webb City
221 S East Street,
Webb City, MO, 64870, US
36.3 km from Seneca, MO
4.73 stars rating. Exceptional. 629 reviews4.73 stars rating. Exceptional. 629 reviews
Book Now & Save 15%
Strikethrough Rate:~~$167~~Discounted rate:$142USD/night
Member Rate
See Availability

Change your dates to book properties below.

Quality Inn
3085 Gardner-Edgewood Dr,
Neosho, MO, 64850, US
19.53 km from Seneca, MO
No Reviews YetNo Reviews Yet
Coming soonStart booking Nov 14, 2025
See Availability

Other Seneca searches

All Hotels in Seneca

Boutique Hotels in Seneca

Hotel Deals in Seneca

Extended Stay Hotels in Seneca

Pet Friendly Hotels in Seneca

Good to know

Top-Rated hotels

6 hotels in Seneca

Highest Price

$142

Lowest Price

$71

Avg. rating

3.3 (4124 reviews)