Book Ascend Hotels in Santa Fe, TX

Comfort Inn & Suites Texas City I-45
10700 Emmett F. Lowry Expwy,
Texas City, TX, 77591, US
4.99 mi from Santa Fe, TX, US
2.31 stars rating. Fair. 61 reviews
Book Now & Save 7%
Strikethrough Rate:~~$72~~Discounted rate:$67USD/night
Member Rate
See Availability
Quality Inn Texas City I-45
2320 FM 2004,
Texas City, TX, 77591, US
5.01 mi from Santa Fe, TX, US
3.51 stars rating. Good. 500 reviews
Book Now & Save 7%
Strikethrough Rate:~~$72~~Discounted rate:$67USD/night
Member Rate
See Availability
Comfort Suites near NASA - Clear Lake
16931 N. Texas Ave,
Webster, TX, 77598, US
11.46 mi from Santa Fe, TX, US
3.87 stars rating. Good. 1183 reviews
Book Now & Save 5%
Strikethrough Rate:~~$89~~Discounted rate:$85USD/night
Member Rate
See Availability
NEW HOTEL
Seabreeze Hotel, an Ascend Collection Hotel
2311 Avenue P 1 2,
Galveston, TX, 77550, US
20.02 mi from Santa Fe, TX, US
4.55 stars rating. Excellent. 127 reviews
Book Now & Save 10%
Strikethrough Rate:~~$99~~Discounted rate:$89USD/night
Member Rate
See Availability
AWARD WINNER
Quality Inn & Suites Seabrook- NASA- Kemah
2720 Nasa Parkway,
Seabrook, TX, 77586, US
13.23 mi from Santa Fe, TX, US
4.41 stars rating. Excellent. 1268 reviews
Book Now & Save 10%
Strikethrough Rate:~~$105~~Discounted rate:$95USD/night
Member Rate
See Availability
MainStay Suites Houston NASA/Clear Lake
1050 Bay Area Blvd,
Houston, TX, 77058, US
12.26 mi from Santa Fe, TX, US
3.59 stars rating. Good. 116 reviews
Book Now & Save 7%
Strikethrough Rate:~~$89~~Discounted rate:$83USD/night
Member Rate
See Availability
Comfort Suites Seabrook - Kemah
5755 Bayport Blvd,
Seabrook, TX, 77586, US
15.44 mi from Santa Fe, TX, US
3.23 stars rating. Good. 284 reviews
Book Now & Save 10%
Strikethrough Rate:~~$75~~Discounted rate:$68USD/night
Member Rate
See Availability
Comfort Suites Galveston Cruise Port Area - Beachside
3606 89th Street,
Galveston, TX, 77554, US
17.54 mi from Santa Fe, TX, US
3.46 stars rating. Good. 1743 reviews
Book Now & Save 10%
Strikethrough Rate:~~$104~~Discounted rate:$94USD/night
Member Rate
See Availability
Quality Inn & Suites Galveston - Beachfront
5924 Seawall Blvd.,
Galveston, TX, 77551, US
18.59 mi from Santa Fe, TX, US
4.02 stars rating. Very Good. 3269 reviews
Book Now & Save 10%
Strikethrough Rate:~~$85~~Discounted rate:$77USD/night
Member Rate
See Availability
MainStay Suites Texas Medical Center/Reliant Park
3134 Old Spanish Trail,
Houston, TX, 77054, US
27.59 mi from Santa Fe, TX, US
3.95 stars rating. Good. 2431 reviews
Book Now & Save 7%
Strikethrough Rate:~~$89~~Discounted rate:$83USD/night
Member Rate
See Availability
Sleep Inn & Suites Galveston Island
6628 Broadway Street,
Galveston, TX, 77554, US
16.78 mi from Santa Fe, TX, US
2.93 stars rating. Fair. 874 reviews
Book Now & Save 7%
Strikethrough Rate:~~$74~~Discounted rate:$69USD/night
Member Rate
See Availability
FULLY RENOVATED
Clarion Pointe Galveston - Beachfront
5914 Seawall Blvd,
Galveston, TX, 77551, US
18.62 mi from Santa Fe, TX, US
3.45 stars rating. Good. 65 reviews
Book Now & Save 10%
Strikethrough Rate:~~$75~~Discounted rate:$68USD/night
Member Rate
See Availability
Comfort Suites Deer Park Pasadena
1501 Center St.,
Deer Park, TX, 77536, US
22.08 mi from Santa Fe, TX, US
3.95 stars rating. Good. 583 reviews
Book Now & Save 10%
Strikethrough Rate:~~$80~~Discounted rate:$72USD/night
Member Rate
See Availability
Comfort Suites Channelview - Houston East
15813 2nd Street,
Channelview, TX, 77530, US
27.72 mi from Santa Fe, TX, US
3.2 stars rating. Good. 318 reviews
Book Now & Save 7%
Strikethrough Rate:~~$83~~Discounted rate:$78USD/night
Member Rate
See Availability
Econo Lodge Inn & Suites East Houston I-10
1016 Maxey Road,
Houston, TX, 77015, US
27.96 mi from Santa Fe, TX, US
4.04 stars rating. Very Good. 390 reviews
Book Now & Save 10%
Strikethrough Rate:~~$67~~Discounted rate:$60USD/night
Member Rate
See Availability
Quality Inn Houston East I-10
828 Mercury Drive,
Houston, TX, 77013, US
28.67 mi from Santa Fe, TX, US
2.96 stars rating. Fair. 475 reviews
Book Now & Save 15%
Strikethrough Rate:~~$74~~Discounted rate:$63USD/night
Member Rate
See Availability
Quality Suites Houston Hobby Airport
7775 Airport Blvd,
Houston, TX, 77061, US
21.99 mi from Santa Fe, TX, US
3.94 stars rating. Good. 244 reviews
Book Now & Save 10%
Strikethrough Rate:~~$89~~Discounted rate:$80USD/night
Member Rate
See Availability
Sleep Inn & Suites Pearland - Houston South
1908 Country Place Parkway,
Pearland, TX, 77584, US
21.64 mi from Santa Fe, TX, US
3.95 stars rating. Good. 683 reviews
Book Now & Save 10%
Strikethrough Rate:~~$101~~Discounted rate:$91USD/night
Member Rate
See Availability
Comfort Inn & Suites Galveston Central Island near Pier
2818 Avenue R 1 2,
Galveston, TX, 77550, US
19.84 mi from Santa Fe, TX, US
3.26 stars rating. Good. 265 reviews
Book Now & Save 7%
Strikethrough Rate:~~$89~~Discounted rate:$83USD/night
Member Rate
See Availability
Econo Lodge Inn & Suites Channelview - Houston East
16007 East Fwy,
Channelview, TX, 77530, US
27.79 mi from Santa Fe, TX, US
3.73 stars rating. Good. 22 reviews
Book Now & Save 7%
Strikethrough Rate:~~$67~~Discounted rate:$62USD/night
Member Rate
See Availability
Quality Inn & Suites NRG Park - Medical Center
2364 South Loop West,
Houston, TX, 77054, US
27.85 mi from Santa Fe, TX, US
3.03 stars rating. Fair. 1501 reviews
Book Now & Save 10%
Strikethrough Rate:~~$90~~Discounted rate:$81USD/night
Member Rate
See Availability
Quality Inn Pasadena - Houston East
114 S. Richey St.,
Pasadena, TX, 77506, US
23.99 mi from Santa Fe, TX, US
3.8 stars rating. Good. 317 reviews
Book Now & Save 7%
Strikethrough Rate:~~$104~~Discounted rate:$97USD/night
Member Rate
See Availability
Econo Lodge Galveston Seawall
3008 Seawall Blvd,
Galveston, TX, 77550-7677, US
19.79 mi from Santa Fe, TX, US
2.78 stars rating. Fair. 128 reviews
Book Now & Save 5%
Strikethrough Rate:~~$60~~Discounted rate:$57USD/night
Member Rate
See Availability
Rodeway Inn & Suites Houston near Medical Center
6712 Morningside Drive,
Houston, TX, 77030, US
29.31 mi from Santa Fe, TX, US
2.51 stars rating. Fair. 409 reviews
Book Now & Save 16%
Strikethrough Rate:~~$75~~Discounted rate:$63USD/night
Member Rate
See Availability

Change your dates to book properties below.

Comfort Suites Houston near Medical Center- NRG Stadium
1055 McNee Road, East of Main Street,
Houston, TX, 77054, US
28.48 mi from Santa Fe, TX, US
4.31 stars rating. Excellent. 1881 reviews
Sold outfor your selected dates
See Availability

Santa Fe hotels by brand

Clarion Hotels

Comfort Inn Hotels

Comfort Suites Hotels

Good to know

Number of hotels

24 of 25 hotels in Santa Fe

Highest Price

$97

Lowest Price

$57

Avg. rating

24 hotels near Santa Fe, TX, US

Comfort Inn & Suites Texas City I-45

Quality Inn Texas City I-45

Comfort Suites near NASA - Clear Lake

Seabreeze Hotel, an Ascend Collection Hotel

Quality Inn & Suites Seabrook- NASA- Kemah

MainStay Suites Houston NASA/Clear Lake

Comfort Suites Seabrook - Kemah

Comfort Suites Galveston Cruise Port Area - Beachside

Quality Inn & Suites Galveston - Beachfront

MainStay Suites Texas Medical Center/Reliant Park

Sleep Inn & Suites Galveston Island

Clarion Pointe Galveston - Beachfront

Comfort Suites Deer Park Pasadena

Comfort Suites Channelview - Houston East

Econo Lodge Inn & Suites East Houston I-10

Quality Inn Houston East I-10

Quality Suites Houston Hobby Airport

Sleep Inn & Suites Pearland - Houston South

Comfort Inn & Suites Galveston Central Island near Pier

Econo Lodge Inn & Suites Channelview - Houston East

Quality Inn & Suites NRG Park - Medical Center

Quality Inn Pasadena - Houston East

Econo Lodge Galveston Seawall

Rodeway Inn & Suites Houston near Medical Center

Change your dates to book properties below.

Comfort Suites Houston near Medical Center- NRG Stadium

Other Santa Fe searches

Santa Fe hotels by brand

Good to know

24 of 25 hotels in Santa Fe

$97

$57

3.5 (19137 reviews)