Hotels in Santa Fe, TX – Choice Hotels

Comfort Inn & Suites Texas City I-45
10700 Emmett F. Lowry Expwy,
Texas City, TX, 77591, US
8.02 km from Santa Fe, TX, USA
2.22 stars rating. Fair. 45 reviews2.22 stars rating. Fair. 45 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$94USD/night
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AWARD WINNER
Quality Inn & Suites Seabrook- NASA- Kemah
2720 Nasa Parkway,
Seabrook, TX, 77586, US
21.3 km from Santa Fe, TX, USA
4.4 stars rating. Excellent. 1245 reviews4.4 stars rating. Excellent. 1245 reviews
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Strikethrough Rate:~~$108~~Discounted rate:$97USD/night
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Comfort Suites near NASA - Clear Lake
16931 N. Texas Ave,
Webster, TX, 77598, US
18.44 km from Santa Fe, TX, USA
3.88 stars rating. Good. 1165 reviews3.88 stars rating. Good. 1165 reviews
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Strikethrough Rate:~~$120~~Discounted rate:$108USD/night
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MainStay Suites Houston NASA/Clear Lake
1050 Bay Area Blvd,
Houston, TX, 77058, US
19.73 km from Santa Fe, TX, USA
3.52 stars rating. Good. 107 reviews3.52 stars rating. Good. 107 reviews
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Strikethrough Rate:~~$79~~Discounted rate:$75USD/night
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Comfort Suites Seabrook - Kemah
5755 Bayport Blvd,
Seabrook, TX, 77586, US
24.85 km from Santa Fe, TX, USA
3.25 stars rating. Good. 274 reviews3.25 stars rating. Good. 274 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$69USD/night
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Comfort Suites La Porte - Baytown
902 South 8th Street,
La Porte, TX, 77571, US
31.56 km from Santa Fe, TX, USA
4.2 stars rating. Excellent. 688 reviews4.2 stars rating. Excellent. 688 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$88USD/night
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MainStay Suites Texas Medical Center/Reliant Park
3134 Old Spanish Trail,
Houston, TX, 77054, US
44.4 km from Santa Fe, TX, USA
3.96 stars rating. Good. 2386 reviews3.96 stars rating. Good. 2386 reviews
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Strikethrough Rate:~~$79~~Discounted rate:$73USD/night
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Comfort Suites Channelview - Houston East
15813 2nd Street,
Channelview, TX, 77530, US
44.61 km from Santa Fe, TX, USA
3.26 stars rating. Good. 308 reviews3.26 stars rating. Good. 308 reviews
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Strikethrough Rate:~~$69~~Discounted rate:$66USD/night
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Comfort Suites Houston near Medical Center- NRG Stadium
1055 McNee Road, East of Main Street,
Houston, TX, 77054, US
45.84 km from Santa Fe, TX, USA
4.31 stars rating. Excellent. 1828 reviews4.31 stars rating. Excellent. 1828 reviews
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Strikethrough Rate:~~$112~~Discounted rate:$101USD/night
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Econo Lodge Inn & Suites East Houston I-10
1016 Maxey Road,
Houston, TX, 77015, US
45 km from Santa Fe, TX, USA
4.04 stars rating. Very Good. 387 reviews4.04 stars rating. Very Good. 387 reviews
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Strikethrough Rate:~~$77~~Discounted rate:$69USD/night
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Quality Inn Houston East I-10
828 Mercury Drive,
Houston, TX, 77013, US
46.14 km from Santa Fe, TX, USA
2.98 stars rating. Fair. 461 reviews2.98 stars rating. Fair. 461 reviews
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Strikethrough Rate:~~$63~~Discounted rate:$59USD/night
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Comfort Suites Deer Park Pasadena
1501 Center St.,
Deer Park, TX, 77536, US
35.53 km from Santa Fe, TX, USA
3.95 stars rating. Good. 578 reviews3.95 stars rating. Good. 578 reviews
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Strikethrough Rate:~~$102~~Discounted rate:$87USD/night
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Quality Suites Houston Hobby Airport
7775 Airport Blvd,
Houston, TX, 77061, US
35.39 km from Santa Fe, TX, USA
3.94 stars rating. Good. 226 reviews3.94 stars rating. Good. 226 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$77USD/night
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Rodeway Inn South Houston
2042 Houston Blvd.,
South Houston, TX, 77587, US
32.91 km from Santa Fe, TX, USA
2.96 stars rating. Fair. 119 reviews2.96 stars rating. Fair. 119 reviews
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Strikethrough Rate:~~$57~~Discounted rate:$54USD/night
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Sleep Inn & Suites Pearland - Houston South
1908 Country Place Parkway,
Pearland, TX, 77584, US
34.82 km from Santa Fe, TX, USA
3.96 stars rating. Good. 672 reviews3.96 stars rating. Good. 672 reviews
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Strikethrough Rate:~~$104~~Discounted rate:$94USD/night
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Econo Lodge Inn & Suites Channelview - Houston East
16007 East Fwy,
Channelview, TX, 77530, US
44.72 km from Santa Fe, TX, USA
3.58 stars rating. Good. 19 reviews3.58 stars rating. Good. 19 reviews
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Strikethrough Rate:~~$67~~Discounted rate:$64USD/night
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Quality Inn & Suites NRG Park - Medical Center
2364 South Loop West,
Houston, TX, 77054, US
44.82 km from Santa Fe, TX, USA
3.03 stars rating. Fair. 1484 reviews3.03 stars rating. Fair. 1484 reviews
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Strikethrough Rate:~~$84~~Discounted rate:$75USD/night
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Comfort Suites Galveston Cruise Port Area - Beachside
3606 89th Street,
Galveston, TX, 77554, US
28.22 km from Santa Fe, TX, USA
3.47 stars rating. Good. 1715 reviews3.47 stars rating. Good. 1715 reviews
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Strikethrough Rate:~~$239~~Discounted rate:$215USD/night
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FULLY RENOVATED
Clarion Pointe Galveston - Beachfront
5914 Seawall Blvd,
Galveston, TX, 77551, US
29.96 km from Santa Fe, TX, USA
3.71 stars rating. Good. 34 reviews3.71 stars rating. Good. 34 reviews
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Strikethrough Rate:~~$210~~Discounted rate:$189USD/night
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Rodeway Inn & Suites Houston near Medical Center
6712 Morningside Drive,
Houston, TX, 77030, US
47.17 km from Santa Fe, TX, USA
2.53 stars rating. Fair. 401 reviews2.53 stars rating. Fair. 401 reviews
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Strikethrough Rate:~~$65~~Discounted rate:$56USD/night
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Quality Inn & Suites Galveston - Beachfront
5924 Seawall Blvd.,
Galveston, TX, 77551, US
29.92 km from Santa Fe, TX, USA
4.03 stars rating. Very Good. 3225 reviews4.03 stars rating. Very Good. 3225 reviews
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Strikethrough Rate:~~$220~~Discounted rate:$198USD/night
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Quality Inn Pasadena - Houston East
114 S. Richey St.,
Pasadena, TX, 77506, US
38.61 km from Santa Fe, TX, USA
3.82 stars rating. Good. 314 reviews3.82 stars rating. Good. 314 reviews
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Strikethrough Rate:~~$179~~Discounted rate:$170USD/night
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Quality Inn Texas City I-45
2320 FM 2004,
Texas City, TX, 77591, US
8.06 km from Santa Fe, TX, USA
3.49 stars rating. Good. 487 reviews3.49 stars rating. Good. 487 reviews
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NEW HOTEL
Seabreeze Hotel, an Ascend Collection Hotel
2311 Avenue P 1 2,
Galveston, TX, 77550, US
32.22 km from Santa Fe, TX, USA
4.47 stars rating. Excellent. 97 reviews4.47 stars rating. Excellent. 97 reviews
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Comfort Inn & Suites Galveston Central Island near Pier
2818 Avenue R 1 2,
Galveston, TX, 77550, US
31.92 km from Santa Fe, TX, USA
3.28 stars rating. Good. 239 reviews3.28 stars rating. Good. 239 reviews
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Econo Lodge Galveston Seawall
3008 Seawall Blvd,
Galveston, TX, 77550-7677, US
31.85 km from Santa Fe, TX, USA
2.79 stars rating. Fair. 126 reviews2.79 stars rating. Fair. 126 reviews
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Sleep Inn & Suites Galveston Island
6628 Broadway Street,
Galveston, TX, 77554, US
27.01 km from Santa Fe, TX, USA
2.95 stars rating. Fair. 859 reviews2.95 stars rating. Fair. 859 reviews
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Good to know

Number of hotels

27 hotels in Santa Fe

Highest Price

$215

Lowest Price

$54

Avg. rating

22 hotels near Santa Fe, TX, USA

Comfort Inn & Suites Texas City I-45

Quality Inn & Suites Seabrook- NASA- Kemah

Comfort Suites near NASA - Clear Lake

MainStay Suites Houston NASA/Clear Lake

Comfort Suites Seabrook - Kemah

Comfort Suites La Porte - Baytown

MainStay Suites Texas Medical Center/Reliant Park

Comfort Suites Channelview - Houston East

Comfort Suites Houston near Medical Center- NRG Stadium

Econo Lodge Inn & Suites East Houston I-10

Quality Inn Houston East I-10

Comfort Suites Deer Park Pasadena

Quality Suites Houston Hobby Airport

Rodeway Inn South Houston

Sleep Inn & Suites Pearland - Houston South

Econo Lodge Inn & Suites Channelview - Houston East

Quality Inn & Suites NRG Park - Medical Center

Comfort Suites Galveston Cruise Port Area - Beachside

Clarion Pointe Galveston - Beachfront

Rodeway Inn & Suites Houston near Medical Center

Quality Inn & Suites Galveston - Beachfront

Quality Inn Pasadena - Houston East

Change your dates to book properties below.

Quality Inn Texas City I-45

Seabreeze Hotel, an Ascend Collection Hotel

Comfort Inn & Suites Galveston Central Island near Pier

Econo Lodge Galveston Seawall

Sleep Inn & Suites Galveston Island

Other Santa Fe searches

Good to know

27 hotels in Santa Fe

$215

$54

3.6 (19489 reviews)