Book Top Rated Hotels in Roxana, IL

Comfort Inn Edwardsville - St. Louis
3080 S. SR 157,
Edwardsville, IL, 62025, US
10.27 km from Roxana, IL, US
4.16 stars rating. Very Good. 1386 reviews
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Strikethrough Rate:~~$137~~Discounted rate:$123USD/night
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Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
8.81 km from Roxana, IL, US
3.64 stars rating. Good. 867 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$98USD/night
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Comfort Inn Collinsville near St. Louis
8 Commerce Dr.,
Collinsville, IL, 62234, US
18.56 km from Roxana, IL, US
4.2 stars rating. Excellent. 1980 reviews
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Strikethrough Rate:~~$154~~Discounted rate:$139USD/night
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The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
8.83 km from Roxana, IL, US
2.91 stars rating. Fair. 114 reviews
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Strikethrough Rate:~~$149~~Discounted rate:$142USD/night
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Econo Lodge Inn & Suites Granite City - St. Louis
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
10.77 km from Roxana, IL, US
3.45 stars rating. Good. 395 reviews
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Strikethrough Rate:~~$75~~Discounted rate:$70USD/night
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Comfort Inn & Suites Hazelwood - St. Louis
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
26.65 km from Roxana, IL, US
4.1 stars rating. Very Good. 2006 reviews
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Strikethrough Rate:~~$101~~Discounted rate:$94USD/night
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Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
25.1 km from Roxana, IL, US
3.41 stars rating. Good. 1482 reviews
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Strikethrough Rate:~~$77~~Discounted rate:$72USD/night
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AWARD WINNER
Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
44.28 km from Roxana, IL, US
4.73 stars rating. Exceptional. 2058 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$111USD/night
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Quality Inn O'Fallon IL - St. Louis
1409 W US 50,
O Fallon, IL, 62269, US
29.83 km from Roxana, IL, US
3.54 stars rating. Good. 957 reviews
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Strikethrough Rate:~~$76~~Discounted rate:$69USD/night
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Comfort Suites Fairview Heights - St Louis
137 Ludwig Drive,
Fairview Heights, IL, 62208, US
27.91 km from Roxana, IL, US
3.45 stars rating. Good. 1820 reviews
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Strikethrough Rate:~~$89~~Discounted rate:$80USD/night
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Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
43.93 km from Roxana, IL, US
4.05 stars rating. Very Good. 237 reviews
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Strikethrough Rate:~~$102~~Discounted rate:$95USD/night
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Econo Lodge Inn & Suites Fairview Heights - St. Louis
305 Salem Place,
Fairview Heights, IL, 62208, US
28.03 km from Roxana, IL, US
3.77 stars rating. Good. 327 reviews
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Strikethrough Rate:~~$75~~Discounted rate:$66USD/night
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Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
31.54 km from Roxana, IL, US
4.07 stars rating. Very Good. 191 reviews
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Strikethrough Rate:~~$105~~Discounted rate:$85USD/night
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Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
38.33 km from Roxana, IL, US
4.02 stars rating. Very Good. 2110 reviews
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Strikethrough Rate:~~$110~~Discounted rate:$105USD/night
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Sleep Inn O'Fallon near I-64
140 Venita Drive,
O Fallon, IL, 62269, US
30.08 km from Roxana, IL, US
3.36 stars rating. Good. 1357 reviews
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Strikethrough Rate:~~$80~~Discounted rate:$74USD/night
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Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive,
Fairview Heights, IL, 62208, US
27.94 km from Roxana, IL, US
3.16 stars rating. Good. 239 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$89USD/night
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AWARD WINNER
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
37.72 km from Roxana, IL, US
4.64 stars rating. Exceptional. 686 reviews
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Strikethrough Rate:~~$174~~Discounted rate:$162USD/night
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Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
33.6 km from Roxana, IL, US
3.52 stars rating. Good. 1360 reviews
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Strikethrough Rate:~~$96~~Discounted rate:$80USD/night
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Quality Inn Saint Louis Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
28.53 km from Roxana, IL, US
3.26 stars rating. Good. 3080 reviews
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Strikethrough Rate:~~$89~~Discounted rate:$83USD/night
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Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy,
Fairview Heights, IL, 62208, US
27.82 km from Roxana, IL, US
3.52 stars rating. Good. 224 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$113USD/night
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Comfort Inn & Suites Saint Louis Lafayette Square
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
29.32 km from Roxana, IL, US
3.79 stars rating. Good. 126 reviews
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Strikethrough Rate:~~$150~~Discounted rate:$139USD/night
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MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
31.52 km from Roxana, IL, US
3.92 stars rating. Good. 244 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$88USD/night
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Quality Inn & Suites Caseyville - St. Louis
2180 Patricia Dr.,
Caseyville, IL, 62232, US
26.14 km from Roxana, IL, US
2.7 stars rating. Fair. 722 reviews
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Strikethrough Rate:~~$100~~Discounted rate:$93USD/night
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Comfort Inn & Suites OFallon - St Louis Area
116 Regency Park,
O'Fallon, IL, 62269, US
30.41 km from Roxana, IL, US
2.36 stars rating. Fair. 128 reviews
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Strikethrough Rate:~~$84~~Discounted rate:$76USD/night
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Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
37.93 km from Roxana, IL, US
No Reviews Yet
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Strikethrough Rate:~~$125~~Discounted rate:$109USD/night
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Sleep Inn Saint Charles North
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
39.82 km from Roxana, IL, US
3.08 stars rating. Fair. 1049 reviews
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Strikethrough Rate:~~$92~~Discounted rate:$86USD/night
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NEW TO CHOICE
Radisson Hotel St. Louis Downtown Convention Center
811 N 9th St,
St. Louis, MO, 63101, US
26.33 km from Roxana, IL, US
1.42 stars rating. Fair. 119 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$113USD/night
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WoodSpring Suites St Louis St Charles
2100 Old Hwy 94 S.,
Saint Charles, MO, 63303, US
42.1 km from Roxana, IL, US
3.22 stars rating. Good. 35 reviews
$80USD/night
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MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
34.07 km from Roxana, IL, US
3.15 stars rating. Good. 211 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$101USD/night
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River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
39.15 km from Roxana, IL, US
No Reviews Yet
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Strikethrough Rate:~~$155~~Discounted rate:$134USD/night
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Roxana hotels by brand

Ascend Hotels

Comfort Inn Hotels

Comfort Suites Hotels

Country Inn Suites Hotels

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Top-Rated hotels

30 hotels in Roxana

Highest Price

$162

Lowest Price

$66

Avg. rating

30 Top Rated hotels near Roxana, IL, US

Comfort Inn Edwardsville - St. Louis

Comfort Inn Alton near I-255

Comfort Inn Collinsville near St. Louis

The Great Rivers, an Ascend Collection Hotel

Econo Lodge Inn & Suites Granite City - St. Louis

Comfort Inn & Suites Hazelwood - St. Louis

Quality Inn Florissant-St. Louis

Comfort Suites St. Louis - Sunset Hills

Quality Inn O'Fallon IL - St. Louis

Comfort Suites Fairview Heights - St Louis

Country Inn & Suites by Radisson, St. Peters, MO

Econo Lodge Inn & Suites Fairview Heights - St. Louis

Comfort Inn St. Louis Airport

Comfort Suites St Charles-St Louis

Sleep Inn O'Fallon near I-64

Country Inn & Suites by Radisson, Fairview Heights, IL

Country Inn & Suites by Radisson, St. Charles Historic District

Quality Inn & Suites near St. Louis and I-255

Quality Inn Saint Louis Airport

Radisson Hotel Fairview Heights - St. Louis

Comfort Inn & Suites Saint Louis Lafayette Square

MainStay Suites St. Louis Airport

Quality Inn & Suites Caseyville - St. Louis

Comfort Inn & Suites OFallon - St Louis Area

Hollywood Casino St Louis

Sleep Inn Saint Charles North

Radisson Hotel St. Louis Downtown Convention Center

WoodSpring Suites St Louis St Charles

MainStay Suites St. Louis - Galleria

River City Casino & Hotel

Other Roxana searches

Roxana hotels by brand

Good to know

30 hotels in Roxana

$162

$66

3.5 (25510 reviews)