Book Boutique Hotels in Jefferson, IA

Below are additional hotels in the area that do not match your exact search criteria.

Sleep Inn & Suites Fort Dodge
110 Leah Lane,
Fort Dodge, IA, 50501, US
53.8 km from Jefferson, IA
4.42 stars rating. Excellent. 821 reviews4.42 stars rating. Excellent. 821 reviews
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Strikethrough Rate:~~$94~~Discounted rate:$89USD/night
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Sleep Inn & Suites Ames near ISU Campus
1310 Dickinson Avenue,
Ames, IA, 50014, US
57.48 km from Jefferson, IA
4.32 stars rating. Excellent. 1316 reviews4.32 stars rating. Excellent. 1316 reviews
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Strikethrough Rate:~~$94~~Discounted rate:$85USD/night
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Comfort Inn & Suites Ankeny - Des Moines
215 NE Delaware Ave,
Ankeny, IA, 50021, US
73.09 km from Jefferson, IA
4.33 stars rating. Excellent. 508 reviews4.33 stars rating. Excellent. 508 reviews
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Strikethrough Rate:~~$98~~Discounted rate:$79USD/night
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Comfort Inn
425 Timberland Drive,
Story City, IA, 50248, US
69.13 km from Jefferson, IA
4.4 stars rating. Excellent. 986 reviews4.4 stars rating. Excellent. 986 reviews
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Strikethrough Rate:~~$105~~Discounted rate:$93USD/night
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Quality Inn Fort Dodge
2001 Hwy 169 South, Building A,
Fort Dodge, IA, 50501, US
53.24 km from Jefferson, IA
3.57 stars rating. Good. 639 reviews3.57 stars rating. Good. 639 reviews
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Strikethrough Rate:~~$74~~Discounted rate:$69USD/night
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Sleep Inn & Suites West Des Moines near Jordan Creek
885 S. 51st Street,
West Des Moines, IA, 50265, US
71.35 km from Jefferson, IA
4.41 stars rating. Excellent. 1237 reviews4.41 stars rating. Excellent. 1237 reviews
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Strikethrough Rate:~~$95~~Discounted rate:$85USD/night
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Suburban Studios Fort Dodge
2001 Hwy 169 South, Building B,
Fort Dodge, IA, 50501, US
53.2 km from Jefferson, IA
3.2 stars rating. Good. 30 reviews3.2 stars rating. Good. 30 reviews
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Strikethrough Rate:~~$68~~Discounted rate:$63USD/night
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Econo Lodge Ankeny - Des Moines
2602 SE Creekview Drive,
Ankeny, IA, 50021, US
75.11 km from Jefferson, IA
4.36 stars rating. Excellent. 1013 reviews4.36 stars rating. Excellent. 1013 reviews
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Strikethrough Rate:~~$79~~Discounted rate:$73USD/night
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Sleep Inn & Suites Ankeny - Des Moines
2406 SE Tones Drive,
Ankeny, IA, 50021, US
74.75 km from Jefferson, IA
4.33 stars rating. Excellent. 793 reviews4.33 stars rating. Excellent. 793 reviews
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Strikethrough Rate:~~$106~~Discounted rate:$91USD/night
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Comfort Inn & Suites West Des Moines
1625 Jordan Creek Parkway,
West Des Moines, IA, 50266, US
66.14 km from Jefferson, IA
4.11 stars rating. Very Good. 602 reviews4.11 stars rating. Very Good. 602 reviews
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Strikethrough Rate:~~$116~~Discounted rate:$100USD/night
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Quality Inn & Suites Des Moines - Merle Hay Road
4995 N.W. Merle Hay Road,
Des Moines, IA, 50322, US
69.41 km from Jefferson, IA
3.74 stars rating. Good. 1239 reviews3.74 stars rating. Good. 1239 reviews
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Strikethrough Rate:~~$75~~Discounted rate:$63USD/night
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Econo Lodge
2600 SE 16th Street,
Ames, IA, 50010, US
65.95 km from Jefferson, IA
3.64 stars rating. Good. 849 reviews3.64 stars rating. Good. 849 reviews
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Strikethrough Rate:~~$60~~Discounted rate:$56USD/night
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Comfort Inn & Suites Ames near ISU Campus
603 S. 16th Street Ames,
Ames, IA, 50010, US
62.72 km from Jefferson, IA
4.27 stars rating. Excellent. 704 reviews4.27 stars rating. Excellent. 704 reviews
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Strikethrough Rate:~~$115~~Discounted rate:$104USD/night
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Quality Inn
4950 NE 14th Street,
Des Moines, IA, 50313, US
76 km from Jefferson, IA
3.36 stars rating. Good. 834 reviews3.36 stars rating. Good. 834 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$79USD/night
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Country Inn & Suites by Radisson, Des Moines West, IA
1350 NW 118th Street,
Clive, IA, 50325, US
67.5 km from Jefferson, IA
4.4 stars rating. Excellent. 432 reviews4.4 stars rating. Excellent. 432 reviews
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Strikethrough Rate:~~$110~~Discounted rate:$105USD/night
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Comfort Inn & Suites Event Center
929 3rd Street,
Des Moines, IA, 50309, US
78.23 km from Jefferson, IA
4.19 stars rating. Very Good. 3037 reviews4.19 stars rating. Very Good. 3037 reviews
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Strikethrough Rate:~~$151~~Discounted rate:$123USD/night
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Quality Inn & Suites Ankeny-Des Moines
201 SE Delaware Ave,
Ankeny, IA, 50021, US
73.16 km from Jefferson, IA
3.62 stars rating. Good. 933 reviews3.62 stars rating. Good. 933 reviews
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Strikethrough Rate:~~$80~~Discounted rate:$71USD/night
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Sleep Inn Waukee-West Des Moines
2885 Grand Prairie Parkway, Building A,
Waukee, IA, 50263, US
65.57 km from Jefferson, IA
4.39 stars rating. Excellent. 446 reviews4.39 stars rating. Excellent. 446 reviews
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Strikethrough Rate:~~$113~~Discounted rate:$102USD/night
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Quality Inn & Suites Ames Conference Center Near ISU Campus
2601 East 13th Street,
Ames, IA, 50010, US
66.05 km from Jefferson, IA
3.43 stars rating. Good. 1104 reviews3.43 stars rating. Good. 1104 reviews
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Strikethrough Rate:~~$79~~Discounted rate:$73USD/night
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MainStay Suites Waukee-West Des Moines
2885 Grand Prairie Prkwy., Building B,
Waukee, IA, 50263, US
65.57 km from Jefferson, IA
4.2 stars rating. Excellent. 121 reviews4.2 stars rating. Excellent. 121 reviews
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Strikethrough Rate:~~$129~~Discounted rate:$123USD/night
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Country Inn & Suites by Radisson, Ankeny, IA
2510 SE Tones Dr,
Ankeny, IA, 50021, US
75.07 km from Jefferson, IA
3.44 stars rating. Good. 134 reviews3.44 stars rating. Good. 134 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$101USD/night
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Radisson Hotel Ames Conference Center at ISU
2609 University Blvd,
Ames, IA, 50010, US
60.89 km from Jefferson, IA
2.8 stars rating. Fair. 137 reviews2.8 stars rating. Fair. 137 reviews
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Strikethrough Rate:~~$101~~Discounted rate:$91USD/night
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Country Inn & Suites by Radisson, Ames, IA
2605 SE 16th Street,
Ames, IA, 50010, US
65.99 km from Jefferson, IA
3.07 stars rating. 228 reviews3.07 stars rating. 228 reviews
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Strikethrough Rate:~~$114~~Discounted rate:$103USD/night
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Quality Inn
1258 8th St,
West Des Moines, IA, 50265, US
72.51 km from Jefferson, IA
No Reviews YetNo Reviews Yet
Coming soonStart booking Oct 16, 2025
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Good to know

Boutique hotels

24 hotels in Jefferson

Highest Price

$123

Lowest Price

$56

Avg. rating

23 Boutique hotels near Jefferson, IA

Below are additional hotels in the area that do not match your exact search criteria.

Sleep Inn & Suites Fort Dodge

Sleep Inn & Suites Ames near ISU Campus

Comfort Inn & Suites Ankeny - Des Moines

Comfort Inn

Quality Inn Fort Dodge

Sleep Inn & Suites West Des Moines near Jordan Creek

Suburban Studios Fort Dodge

Econo Lodge Ankeny - Des Moines

Sleep Inn & Suites Ankeny - Des Moines

Comfort Inn & Suites West Des Moines

Quality Inn & Suites Des Moines - Merle Hay Road

Econo Lodge

Comfort Inn & Suites Ames near ISU Campus

Quality Inn

Country Inn & Suites by Radisson, Des Moines West, IA

Comfort Inn & Suites Event Center

Quality Inn & Suites Ankeny-Des Moines

Sleep Inn Waukee-West Des Moines

Quality Inn & Suites Ames Conference Center Near ISU Campus

MainStay Suites Waukee-West Des Moines

Country Inn & Suites by Radisson, Ankeny, IA

Radisson Hotel Ames Conference Center at ISU

Country Inn & Suites by Radisson, Ames, IA

Change your dates to book properties below.

Quality Inn

Other Jefferson searches

Good to know

24 hotels in Jefferson

$123

$56

3.8 (18143 reviews)