Hotels in Middletown, MO – Choice Hotels

Below are additional hotels in the area that do not match your exact search criteria.

Quality Inn Foristell
12 Highway W,
Foristell, MO, 63348, US
52.58 km from Middletown, MO, US
4.21 stars rating. Excellent. 935 reviews
Book Now & Save 19%
Strikethrough Rate:~~$165~~Discounted rate:$134USD/night
Member Rate
See Availability
Quality Inn Pacific near Six Flags St. Louis
1400 West Osage St.,
Pacific, MO, 63069, US
91.22 km from Middletown, MO, US
4.01 stars rating. Very Good. 669 reviews
Book Now & Save 10%
Strikethrough Rate:~~$139~~Discounted rate:$125USD/night
Member Rate
See Availability
Comfort Suites Jefferson City
4804 Country Club Drive,
Jefferson City, MO, 65109, US
96.32 km from Middletown, MO, US
4.27 stars rating. Excellent. 1169 reviews
Book Now & Save 5%
Strikethrough Rate:~~$139~~Discounted rate:$132USD/night
Member Rate
See Availability
Quality Inn Kingdom City I-70
3207 County Road 211,
Kingdom City, MO, 65262, US
50.24 km from Middletown, MO, US
3.1 stars rating. Good. 364 reviews
Book Now & Save 10%
Strikethrough Rate:~~$110~~Discounted rate:$99USD/night
Member Rate
See Availability
Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
82.32 km from Middletown, MO, US
4.05 stars rating. Very Good. 237 reviews
Book Now & Save 5%
Strikethrough Rate:~~$165~~Discounted rate:$157USD/night
Member Rate
See Availability
Comfort Inn & Suites - Hannibal
4000 Market Street,
Hannibal, MO, 63401, US
62.12 km from Middletown, MO, US
3.61 stars rating. Good. 1180 reviews
Book Now & Save 10%
Strikethrough Rate:~~$99~~Discounted rate:$89USD/night
Member Rate
See Availability
AWARD WINNER
Quality Inn & Suites Quincy - Downtown
225 S 4th Street,
Quincy, IL, 62301, US
89.26 km from Middletown, MO, US
4.32 stars rating. Excellent. 384 reviews
Book Now & Save 10%
Strikethrough Rate:~~$142~~Discounted rate:$128USD/night
Member Rate
See Availability
Econo Lodge Jefferson City
1926 Jefferson St.,
Jefferson City, MO, 65109, US
93.21 km from Middletown, MO, US
2.8 stars rating. Fair. 303 reviews
Book Now & Save 5%
Strikethrough Rate:~~$100~~Discounted rate:$95USD/night
Member Rate
See Availability
Comfort Inn Near Six Flags St. Louis
1320 Thornton St.,
Pacific, MO, 63069, US
91.09 km from Middletown, MO, US
4.06 stars rating. Very Good. 1786 reviews
Book Now & Save 10%
Strikethrough Rate:~~$166~~Discounted rate:$150USD/night
Member Rate
See Availability
Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
76.22 km from Middletown, MO, US
4.23 stars rating. Excellent. 1283 reviews
Book Now & Save 19%
Strikethrough Rate:~~$214~~Discounted rate:$173USD/night
Member Rate
See Availability
Quality Inn & Suites Jefferson City
1716 Jefferson Street,
Jefferson City, MO, 65109, US
92.59 km from Middletown, MO, US
3.59 stars rating. Good. 831 reviews
Book Now & Save 10%
Strikethrough Rate:~~$129~~Discounted rate:$116USD/night
Member Rate
See Availability
AWARD WINNER
Sleep Inn & Suites Hannibal West
105 Lakeside Drive,
Hannibal, MO, 63401, US
65.21 km from Middletown, MO, US
4.78 stars rating. Exceptional. 1842 reviews
Book Now & Save 10%
Strikethrough Rate:~~$149~~Discounted rate:$134USD/night
Member Rate
See Availability
Quality Inn & Suites Hannibal West
120 Lindsey Drive, Hwy 36,
Hannibal, MO, 63401, US
65.23 km from Middletown, MO, US
3.96 stars rating. Good. 2625 reviews
Book Now & Save 10%
Strikethrough Rate:~~$93~~Discounted rate:$84USD/night
Member Rate
See Availability
Quality Inn & Suites Columbia I-70
801 N. Keene St.,
Columbia, MO, 65201, US
77.84 km from Middletown, MO, US
3.08 stars rating. Fair. 900 reviews
$149USD/night
See Availability
AWARD WINNER
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
89.27 km from Middletown, MO, US
4.64 stars rating. Exceptional. 688 reviews
Book Now & Save 5%
Strikethrough Rate:~~$239~~Discounted rate:$227USD/night
Member Rate
See Availability
Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
82.92 km from Middletown, MO, US
3.89 stars rating. Good. 2522 reviews
Book Now & Save 10%
Strikethrough Rate:~~$184~~Discounted rate:$166USD/night
Member Rate
Fees included
See Availability
Sleep Inn Saint Charles North
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
84.07 km from Middletown, MO, US
3.08 stars rating. Fair. 1050 reviews
Book Now & Save 5%
Strikethrough Rate:~~$104~~Discounted rate:$99USD/night
Member Rate
See Availability
Comfort Inn & Suites St. Louis-O'Fallon
8170 Veterans Memorial Pkwy,
O Fallon, MO, 63366, US
73.1 km from Middletown, MO, US
3.67 stars rating. Good. 1933 reviews
Book Now & Save 3%
Strikethrough Rate:~~$200~~Discounted rate:$194USD/night
Member Rate
See Availability
Country Inn & Suites by Radisson, Columbia, MO
817 North Keene Street,
Columbia, MO, 65201, US
77.74 km from Middletown, MO, US
4.49 stars rating. Excellent. 607 reviews
Book Now & Save 10%
Strikethrough Rate:~~$264~~Discounted rate:$238USD/night
Member Rate
See Availability
Comfort Inn & Suites Moberly
1801 W Outer Road,
Moberly, MO, 65270, US
94.16 km from Middletown, MO, US
4.22 stars rating. Excellent. 1068 reviews
Book Now & Save 5%
Strikethrough Rate:~~$194~~Discounted rate:$184USD/night
Member Rate
See Availability
Comfort Suites Columbia - University Area
1010 W Business Loop 70,
Columbia, MO, 65202, US
83.05 km from Middletown, MO, US
3.83 stars rating. Good. 2196 reviews
Book Now & Save 10%
Strikethrough Rate:~~$289~~Discounted rate:$260USD/night
Member Rate
See Availability
Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
90.45 km from Middletown, MO, US
No Reviews Yet
$265USD/night
Fees included
See Availability
Rodeway Inn Pittsfield
1238 W. Washington St.,
Pittsfield, IL, 62363, US
73.47 km from Middletown, MO, US
2.94 stars rating. Fair. 67 reviews
Book Now & Save 5%
Strikethrough Rate:~~$75~~Discounted rate:$71USD/night
Member Rate
See Availability
NEW TO CHOICE
Econo Lodge Quincy
224 North 36th Street,
Quincy, IL, 62301, US
89.8 km from Middletown, MO, US
1 star rating. Fair. 2 reviews
Book Now & Save 10%
Strikethrough Rate:~~$70~~Discounted rate:$63USD/night
Member Rate
See Availability

Change your dates to book properties below.

Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
88.96 km from Middletown, MO, US
4.02 stars rating. Very Good. 2111 reviews
Sold outfor your selected dates
See Availability

Middletown hotels by brand

Ascend Hotels

Comfort Inn Hotels

Comfort Suites Hotels

Country Inn Suites Hotels

Good to know

Number of hotels

25 hotels in Middletown

Highest Price

$265

Lowest Price

$63

Avg. rating

24 hotels near Middletown, MO, US

Below are additional hotels in the area that do not match your exact search criteria.

Quality Inn Foristell

Quality Inn Pacific near Six Flags St. Louis

Comfort Suites Jefferson City

Quality Inn Kingdom City I-70

Country Inn & Suites by Radisson, St. Peters, MO

Comfort Inn & Suites - Hannibal

Quality Inn & Suites Quincy - Downtown

Econo Lodge Jefferson City

Comfort Inn Near Six Flags St. Louis

Sleep Inn & Suites O'Fallon MO - Technology Drive

Quality Inn & Suites Jefferson City

Sleep Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

Quality Inn & Suites Columbia I-70

Country Inn & Suites by Radisson, St. Charles Historic District

Comfort Inn & Suites Chesterfield - St. Louis

Sleep Inn Saint Charles North

Comfort Inn & Suites St. Louis-O'Fallon

Country Inn & Suites by Radisson, Columbia, MO

Comfort Inn & Suites Moberly

Comfort Suites Columbia - University Area

Hollywood Casino St Louis

Rodeway Inn Pittsfield

Econo Lodge Quincy

Change your dates to book properties below.

Comfort Suites St Charles-St Louis

Other Middletown searches

Middletown hotels by brand

Good to know

25 hotels in Middletown

$265

$63

3.7 (26752 reviews)