Extended Stay Hotels in Saint Charles, MO - Choice Hotels

Below are additional hotels in the area that do not match your exact search criteria.

Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
37.38 km from St Charles, MO, USA
3.54 stars rating. Good. 1342 reviews3.54 stars rating. Good. 1342 reviews
Book Now & Save 6%
Strikethrough Rate:~~$89~~Discounted rate:$84USD/night
Member Rate
See Availability
Quality Inn
12 Highway W,
Foristell, MO, 63348, US
40.97 km from St Charles, MO, USA
4.22 stars rating. Excellent. 917 reviews4.22 stars rating. Excellent. 917 reviews
Book Now & Save 24%
Strikethrough Rate:~~$122~~Discounted rate:$93USD/night
Member Rate
See Availability

Change your dates to book properties below.

Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
1.84 km from St Charles, MO, USA
4.03 stars rating. Very Good. 2052 reviews4.03 stars rating. Very Good. 2052 reviews
Sold outfor your selected dates
See Availability
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
1.28 km from St Charles, MO, USA
4.65 stars rating. Exceptional. 539 reviews4.65 stars rating. Exceptional. 539 reviews
Sold outfor your selected dates
See Availability
Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
3.27 km from St Charles, MO, USA
No Reviews YetNo Reviews Yet
Sold outfor your selected dates
See Availability
Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
7.13 km from St Charles, MO, USA
4.12 stars rating. Very Good. 202 reviews4.12 stars rating. Very Good. 202 reviews
Sold outfor your selected dates
See Availability
Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd.,
Saint Louis, MO, 63146, US
10.01 km from St Charles, MO, USA
3.58 stars rating. Good. 3059 reviews3.58 stars rating. Good. 3059 reviews
Sold outfor your selected dates
See Availability
Quality Inn Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
11.96 km from St Charles, MO, USA
3.28 stars rating. Good. 3012 reviews3.28 stars rating. Good. 3012 reviews
Sold outfor your selected dates
See Availability
Sleep Inn
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
5.82 km from St Charles, MO, USA
3.08 stars rating. 1017 reviews3.08 stars rating. 1017 reviews
Sold outfor your selected dates
See Availability
Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
12.64 km from St Charles, MO, USA
3.42 stars rating. Good. 1439 reviews3.42 stars rating. Good. 1439 reviews
Sold outfor your selected dates
See Availability
Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
8.6 km from St Charles, MO, USA
4.09 stars rating. Very Good. 173 reviews4.09 stars rating. Very Good. 173 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites St. Louis-O'Fallon
100 Comfort Inn Court,
O Fallon, MO, 63366, US
17.19 km from St Charles, MO, USA
3.69 stars rating. Good. 1852 reviews3.69 stars rating. Good. 1852 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites St. Louis-Hazelwood
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
10.88 km from St Charles, MO, USA
4.12 stars rating. Very Good. 1973 reviews4.12 stars rating. Very Good. 1973 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
19.24 km from St Charles, MO, USA
3.93 stars rating. Good. 2433 reviews3.93 stars rating. Good. 2433 reviews
Sold outfor your selected dates
See Availability
MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
8.58 km from St Charles, MO, USA
3.93 stars rating. Good. 234 reviews3.93 stars rating. Good. 234 reviews
Sold outfor your selected dates
See Availability
Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
26.48 km from St Charles, MO, USA
4.71 stars rating. Exceptional. 1810 reviews4.71 stars rating. Exceptional. 1810 reviews
Sold outfor your selected dates
See Availability
River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
33.79 km from St Charles, MO, USA
No Reviews YetNo Reviews Yet
Sold outfor your selected dates
See Availability
Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
20.84 km from St Charles, MO, USA
4.23 stars rating. Excellent. 1211 reviews4.23 stars rating. Excellent. 1211 reviews
Sold outfor your selected dates
See Availability
Radisson Hotel St. Louis Downtown Convention Center
811 N 9th St,
St. Louis, MO, 63101, US
30.14 km from St Charles, MO, USA
No Reviews YetNo Reviews Yet
Coming soonStart booking 29 Oct 2026
See Availability
MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
20.5 km from St Charles, MO, USA
3.23 stars rating. Good. 162 reviews3.23 stars rating. Good. 162 reviews
Sold outfor your selected dates
See Availability
Comfort Inn Near Six Flags St. Louis
1320 Thornton St.,
Pacific, MO, 63069, US
40.77 km from St Charles, MO, USA
4.05 stars rating. Very Good. 1705 reviews4.05 stars rating. Very Good. 1705 reviews
Sold outfor your selected dates
See Availability
Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
33.09 km from St Charles, MO, USA
3.67 stars rating. Good. 846 reviews3.67 stars rating. Good. 846 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
29.25 km from St Charles, MO, USA
3.79 stars rating. Good. 90 reviews3.79 stars rating. Good. 90 reviews
Sold outfor your selected dates
See Availability
Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive,
Fairview Heights, IL, 62208, US
46.89 km from St Charles, MO, USA
3.2 stars rating. Good. 215 reviews3.2 stars rating. Good. 215 reviews
Sold outfor your selected dates
See Availability
Comfort Inn Collinsville near St. Louis
8 Commerce Dr.,
Collinsville, IL, 62234, US
42.06 km from St Charles, MO, USA
4.19 stars rating. Very Good. 1906 reviews4.19 stars rating. Very Good. 1906 reviews
Sold outfor your selected dates
See Availability
Comfort Suites Fairview Heights - St Louis
137 Ludwig Drive,
Fairview Heights, IL, 62208, US
46.86 km from St Charles, MO, USA
3.46 stars rating. Good. 1772 reviews3.46 stars rating. Good. 1772 reviews
Sold outfor your selected dates
See Availability
Quality Inn Near Six Flags St. Louis
1400 West Osage St.,
Pacific, MO, 63069, US
40.96 km from St Charles, MO, USA
4 stars rating. Very Good. 650 reviews4 stars rating. Very Good. 650 reviews
Sold outfor your selected dates
See Availability
Econo Lodge Inn & Suites
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
31.29 km from St Charles, MO, USA
3.45 stars rating. Good. 370 reviews3.45 stars rating. Good. 370 reviews
Sold outfor your selected dates
See Availability
Comfort Inn Edwardsville - St. Louis
3080 S. SR 157,
Edwardsville, IL, 62025, US
41.37 km from St Charles, MO, USA
4.17 stars rating. Very Good. 1354 reviews4.17 stars rating. Very Good. 1354 reviews
Sold outfor your selected dates
See Availability
The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
33.19 km from St Charles, MO, USA
2.84 stars rating. Fair. 85 reviews2.84 stars rating. Fair. 85 reviews
Sold outfor your selected dates
See Availability
Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy,
Fairview Heights, IL, 62208, US
47.64 km from St Charles, MO, USA
3.1 stars rating. Good. 126 reviews3.1 stars rating. Good. 126 reviews
Sold outfor your selected dates
See Availability
Quality Inn & Suites Caseyville - St. Louis
2180 Patricia Dr.,
Caseyville, IL, 62232, US
42.27 km from St Charles, MO, USA
2.73 stars rating. Fair. 704 reviews2.73 stars rating. Fair. 704 reviews
Sold outfor your selected dates
See Availability
Econo Lodge Inn & Suites Fairview Heights - St. Louis
305 Salem Place,
Fairview Heights, IL, 62208, US
47.66 km from St Charles, MO, USA
3.73 stars rating. Good. 314 reviews3.73 stars rating. Good. 314 reviews
Sold outfor your selected dates
See Availability

Other Saint Charles searches

All Hotels in Saint Charles

Boutique Hotels in Saint Charles

Hotel Deals in Saint Charles

Pet Friendly Hotels in Saint Charles

Top Rated Hotels in Saint Charles

Good to know

Extended stay hotels

2 of 33 hotels in Saint Charles

Highest Price

$93

Lowest Price

$84

Avg. rating

3.4 (33564 reviews)

Weekly Rate

$588

Monthly Rate

$2,520