Book Sleep Hotels in Amarillo, TX - Choice Hotels

Sleep Inn & Suites West Medical Center
6915 I-40 West,
Amarillo, TX, 79106, US
8.05 km from Amarillo, TX, USA
4.2 stars rating. Excellent. 1656 reviews4.2 stars rating. Excellent. 1656 reviews
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Strikethrough Rate:~~$79~~Discounted rate:$75USD/night
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Below are additional hotels in the area that do not match your exact search criteria.

Comfort Inn & Suites Amarillo West near Medical Center
2300 Soncy Road,
Amarillo, TX, 79124, US
9.89 km from Amarillo, TX, USA
4.19 stars rating. Very Good. 2715 reviews4.19 stars rating. Very Good. 2715 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$77USD/night
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Comfort Inn & Suites Amarillo East
2101 I-40 East,
Amarillo, TX, 79102, US
2.2 km from Amarillo, TX, USA
4.17 stars rating. Very Good. 2307 reviews4.17 stars rating. Very Good. 2307 reviews
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Strikethrough Rate:~~$104~~Discounted rate:$94USD/night
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Quality Inn Amarillo East
1515 I-40 E.,
Amarillo, TX, 79102, US
1.84 km from Amarillo, TX, USA
2.39 stars rating. Fair. 85 reviews2.39 stars rating. Fair. 85 reviews
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Strikethrough Rate:~~$55~~Discounted rate:$52USD/night
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AWARD WINNER
Econo Lodge Amarillo East
2401 I-40 E.,
Amarillo, TX, 79104, US
2.49 km from Amarillo, TX, USA
3.97 stars rating. Good. 1222 reviews3.97 stars rating. Good. 1222 reviews
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Strikethrough Rate:~~$60~~Discounted rate:$50USD/night
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Country Inn & Suites by Radisson, Amarillo I-40 West, TX
2000 Soncy Road,
Amarillo, TX, 79121, US
9.84 km from Amarillo, TX, USA
4.32 stars rating. Excellent. 640 reviews4.32 stars rating. Excellent. 640 reviews
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Strikethrough Rate:~~$95~~Discounted rate:$88USD/night
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Quality Inn Amarillo West near Medical Center
1610 S. Coulter Street,
Amarillo, TX, 79106, US
8.29 km from Amarillo, TX, USA
1.92 stars rating. Fair. 434 reviews1.92 stars rating. Fair. 434 reviews
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Strikethrough Rate:~~$57~~Discounted rate:$48USD/night
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NEW HOTEL
EXTENDED STAY
Everhome Suites Amarillo West - Medical Center
11 Care Circle,
Amarillo, TX, 79124, US
8.87 km from Amarillo, TX, USA
4.4 stars rating. Excellent. 47 reviews4.4 stars rating. Excellent. 47 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$92USD/night
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NEW HOTEL
Country Inn & Suites by Radisson, Amarillo Central
2111 E I-40,
Amarillo, TX, 79104, US
2.17 km from Amarillo, TX, USA
No Reviews YetNo Reviews Yet
Coming soonStart booking 02 Mar 2026
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Good to know

Number of hotels

8 of 9 hotels in Amarillo

Highest Price

$94

Lowest Price

$48

Avg. rating

3.3 (9106 reviews)