Book Top Rated Hotels in Middletown, MO

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Quality Inn Kingdom City I-70
3207 County Road 211,
Kingdom City, MO, 65262, US
50.24 km from Middletown, MO, US
3.1 stars rating. Good. 364 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$89USD/night
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Quality Inn Foristell
12 Highway W,
Foristell, MO, 63348, US
52.58 km from Middletown, MO, US
4.21 stars rating. Excellent. 935 reviews
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Strikethrough Rate:~~$152~~Discounted rate:$123USD/night
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Comfort Inn & Suites - Hannibal
4000 Market Street,
Hannibal, MO, 63401, US
62.12 km from Middletown, MO, US
3.61 stars rating. Good. 1180 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$89USD/night
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Quality Inn Pacific near Six Flags St. Louis
1400 West Osage St.,
Pacific, MO, 63069, US
91.22 km from Middletown, MO, US
4.01 stars rating. Very Good. 669 reviews
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Strikethrough Rate:~~$139~~Discounted rate:$125USD/night
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Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
82.32 km from Middletown, MO, US
4.05 stars rating. Very Good. 237 reviews
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Strikethrough Rate:~~$165~~Discounted rate:$157USD/night
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Econo Lodge Jefferson City
1926 Jefferson St.,
Jefferson City, MO, 65109, US
93.21 km from Middletown, MO, US
2.8 stars rating. Fair. 303 reviews
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Strikethrough Rate:~~$100~~Discounted rate:$95USD/night
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Comfort Suites Jefferson City
4804 Country Club Drive,
Jefferson City, MO, 65109, US
96.32 km from Middletown, MO, US
4.27 stars rating. Excellent. 1169 reviews
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Strikethrough Rate:~~$139~~Discounted rate:$132USD/night
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Comfort Inn Near Six Flags St. Louis
1320 Thornton St.,
Pacific, MO, 63069, US
91.09 km from Middletown, MO, US
4.06 stars rating. Very Good. 1786 reviews
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Strikethrough Rate:~~$166~~Discounted rate:$149USD/night
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Quality Inn & Suites Jefferson City
1716 Jefferson Street,
Jefferson City, MO, 65109, US
92.59 km from Middletown, MO, US
3.59 stars rating. Good. 831 reviews
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Strikethrough Rate:~~$129~~Discounted rate:$116USD/night
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AWARD WINNER
Quality Inn & Suites Quincy - Downtown
225 S 4th Street,
Quincy, IL, 62301, US
89.26 km from Middletown, MO, US
4.32 stars rating. Excellent. 384 reviews
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Strikethrough Rate:~~$141~~Discounted rate:$127USD/night
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Quality Inn & Suites Hannibal West
120 Lindsey Drive, Hwy 36,
Hannibal, MO, 63401, US
65.23 km from Middletown, MO, US
3.96 stars rating. Good. 2625 reviews
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Strikethrough Rate:~~$93~~Discounted rate:$84USD/night
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AWARD WINNER
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
89.27 km from Middletown, MO, US
4.64 stars rating. Exceptional. 688 reviews
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Strikethrough Rate:~~$239~~Discounted rate:$227USD/night
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Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
88.96 km from Middletown, MO, US
4.02 stars rating. Very Good. 2111 reviews
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Strikethrough Rate:~~$239~~Discounted rate:$227USD/night
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AWARD WINNER
Sleep Inn & Suites Hannibal West
105 Lakeside Drive,
Hannibal, MO, 63401, US
65.21 km from Middletown, MO, US
4.78 stars rating. Exceptional. 1842 reviews
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Strikethrough Rate:~~$149~~Discounted rate:$134USD/night
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Sleep Inn Saint Charles North
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
84.07 km from Middletown, MO, US
3.08 stars rating. Fair. 1050 reviews
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Strikethrough Rate:~~$104~~Discounted rate:$99USD/night
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Country Inn & Suites by Radisson, Columbia, MO
817 North Keene Street,
Columbia, MO, 65201, US
77.74 km from Middletown, MO, US
4.49 stars rating. Excellent. 607 reviews
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Strikethrough Rate:~~$259~~Discounted rate:$233USD/night
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Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
82.92 km from Middletown, MO, US
3.89 stars rating. Good. 2522 reviews
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Strikethrough Rate:~~$200~~Discounted rate:$194USD/night
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Comfort Inn & Suites St. Louis-O'Fallon
8170 Veterans Memorial Pkwy,
O Fallon, MO, 63366, US
73.1 km from Middletown, MO, US
3.67 stars rating. Good. 1933 reviews
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Strikethrough Rate:~~$200~~Discounted rate:$194USD/night
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Quality Inn & Suites Columbia I-70
801 N. Keene St.,
Columbia, MO, 65201, US
77.84 km from Middletown, MO, US
3.08 stars rating. Fair. 900 reviews
$149USD/night
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Comfort Inn & Suites Moberly
1801 W Outer Road,
Moberly, MO, 65270, US
94.16 km from Middletown, MO, US
4.22 stars rating. Excellent. 1068 reviews
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Strikethrough Rate:~~$194~~Discounted rate:$184USD/night
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Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
76.22 km from Middletown, MO, US
4.23 stars rating. Excellent. 1283 reviews
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Strikethrough Rate:~~$234~~Discounted rate:$190USD/night
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Comfort Suites Columbia - University Area
1010 W Business Loop 70,
Columbia, MO, 65202, US
83.05 km from Middletown, MO, US
3.83 stars rating. Good. 2196 reviews
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Strikethrough Rate:~~$289~~Discounted rate:$260USD/night
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Rodeway Inn Pittsfield
1238 W. Washington St.,
Pittsfield, IL, 62363, US
73.47 km from Middletown, MO, US
2.94 stars rating. Fair. 67 reviews
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Strikethrough Rate:~~$75~~Discounted rate:$71USD/night
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NEW TO CHOICE
Econo Lodge Quincy
224 North 36th Street,
Quincy, IL, 62301, US
89.8 km from Middletown, MO, US
1 star rating. Fair. 2 reviews
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Strikethrough Rate:~~$70~~Discounted rate:$63USD/night
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Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
90.45 km from Middletown, MO, US
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Strikethrough Rate:~~$215~~Discounted rate:$185USD/night
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Middletown hotels by brand

Ascend Hotels

Comfort Inn Hotels

Comfort Suites Hotels

Country Inn Suites Hotels

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Top-Rated hotels

25 hotels in Middletown

Highest Price

$260

Lowest Price

$63

Avg. rating

25 Top Rated hotels near Middletown, MO, US

Below are additional hotels in the area that do not match your exact search criteria.

Quality Inn Kingdom City I-70

Quality Inn Foristell

Comfort Inn & Suites - Hannibal

Quality Inn Pacific near Six Flags St. Louis

Country Inn & Suites by Radisson, St. Peters, MO

Econo Lodge Jefferson City

Comfort Suites Jefferson City

Comfort Inn Near Six Flags St. Louis

Quality Inn & Suites Jefferson City

Quality Inn & Suites Quincy - Downtown

Quality Inn & Suites Hannibal West

Country Inn & Suites by Radisson, St. Charles Historic District

Comfort Suites St Charles-St Louis

Sleep Inn & Suites Hannibal West

Sleep Inn Saint Charles North

Country Inn & Suites by Radisson, Columbia, MO

Comfort Inn & Suites Chesterfield - St. Louis

Comfort Inn & Suites St. Louis-O'Fallon

Quality Inn & Suites Columbia I-70

Comfort Inn & Suites Moberly

Sleep Inn & Suites O'Fallon MO - Technology Drive

Comfort Suites Columbia - University Area

Rodeway Inn Pittsfield

Econo Lodge Quincy

Hollywood Casino St Louis

Other Middletown searches

Middletown hotels by brand

Good to know

25 hotels in Middletown

$260

$63

3.7 (26752 reviews)