Book Boutique Hotels in Clayton, MO | Choice Hotels

Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd.,
Saint Louis, MO, 63146, US
10.72 km from Clayton, MO, USA
3.57 stars rating. Good. 3079 reviews3.57 stars rating. Good. 3079 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$87USD/night
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Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
11.43 km from Clayton, MO, USA
4.07 stars rating. Very Good. 178 reviews4.07 stars rating. Very Good. 178 reviews
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Strikethrough Rate:~~$101~~Discounted rate:$85USD/night
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MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
1.92 km from Clayton, MO, USA
3.22 stars rating. Good. 166 reviews3.22 stars rating. Good. 166 reviews
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Strikethrough Rate:~~$139~~Discounted rate:$116USD/night
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Comfort Inn & Suites St. Louis-Hazelwood
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
14.48 km from Clayton, MO, USA
4.12 stars rating. Very Good. 1977 reviews4.12 stars rating. Very Good. 1977 reviews
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Strikethrough Rate:~~$95~~Discounted rate:$84USD/night
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Radisson Hotel St. Louis Downtown Convention Center
811 N 9th St,
St. Louis, MO, 63101, US
12.71 km from Clayton, MO, USA
No Reviews YetNo Reviews Yet
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Strikethrough Rate:~~$129~~Discounted rate:$123USD/night
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Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
12.37 km from Clayton, MO, USA
4.71 stars rating. Exceptional. 1839 reviews4.71 stars rating. Exceptional. 1839 reviews
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Strikethrough Rate:~~$129~~Discounted rate:$120USD/night
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Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
14.02 km from Clayton, MO, USA
3.41 stars rating. Good. 1451 reviews3.41 stars rating. Good. 1451 reviews
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Strikethrough Rate:~~$74~~Discounted rate:$69USD/night
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Quality Inn Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
9.69 km from Clayton, MO, USA
3.27 stars rating. Good. 3025 reviews3.27 stars rating. Good. 3025 reviews
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Strikethrough Rate:~~$84~~Discounted rate:$78USD/night
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Comfort Inn & Suites
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
10.69 km from Clayton, MO, USA
3.81 stars rating. Good. 93 reviews3.81 stars rating. Good. 93 reviews
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Strikethrough Rate:~~$122~~Discounted rate:$113USD/night
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Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
18.3 km from Clayton, MO, USA
3.54 stars rating. Good. 1344 reviews3.54 stars rating. Good. 1344 reviews
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Strikethrough Rate:~~$79~~Discounted rate:$73USD/night
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Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
18.85 km from Clayton, MO, USA
4.02 stars rating. Very Good. 2071 reviews4.02 stars rating. Very Good. 2071 reviews
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Strikethrough Rate:~~$104~~Discounted rate:$97USD/night
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Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
18.75 km from Clayton, MO, USA
4.65 stars rating. Exceptional. 571 reviews4.65 stars rating. Exceptional. 571 reviews
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Strikethrough Rate:~~$137~~Discounted rate:$127USD/night
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River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
14.64 km from Clayton, MO, USA
No Reviews YetNo Reviews Yet
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Strikethrough Rate:~~$125~~Discounted rate:$109USD/night
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MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
11.47 km from Clayton, MO, USA
3.93 stars rating. Good. 234 reviews3.93 stars rating. Good. 234 reviews
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Strikethrough Rate:~~$121~~Discounted rate:$101USD/night
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Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
27.48 km from Clayton, MO, USA
3.92 stars rating. Good. 2443 reviews3.92 stars rating. Good. 2443 reviews
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Strikethrough Rate:~~$103~~Discounted rate:$84USD/night
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Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
25.19 km from Clayton, MO, USA
4.12 stars rating. Very Good. 208 reviews4.12 stars rating. Very Good. 208 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$92USD/night
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Sleep Inn O'Fallon near I-64
140 Venita Drive,
O Fallon, IL, 62269, US
35.19 km from Clayton, MO, USA
3.39 stars rating. Good. 1323 reviews3.39 stars rating. Good. 1323 reviews
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Strikethrough Rate:~~$54~~Discounted rate:$48USD/night
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Comfort Inn Collinsville near St. Louis
8 Commerce Dr.,
Collinsville, IL, 62234, US
28.34 km from Clayton, MO, USA
4.19 stars rating. Very Good. 1919 reviews4.19 stars rating. Very Good. 1919 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$96USD/night
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Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
17.1 km from Clayton, MO, USA
No Reviews YetNo Reviews Yet
$165USD/night
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Sleep Inn
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
25.22 km from Clayton, MO, USA
3.08 stars rating. 1021 reviews3.08 stars rating. 1021 reviews
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Strikethrough Rate:~~$82~~Discounted rate:$76USD/night
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Quality Inn & Suites Caseyville - St. Louis
2180 Patricia Dr.,
Caseyville, IL, 62232, US
25.59 km from Clayton, MO, USA
2.73 stars rating. Fair. 706 reviews2.73 stars rating. Fair. 706 reviews
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Strikethrough Rate:~~$67~~Discounted rate:$62USD/night
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Econo Lodge Inn & Suites
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
22.47 km from Clayton, MO, USA
3.43 stars rating. Good. 373 reviews3.43 stars rating. Good. 373 reviews
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Strikethrough Rate:~~$69~~Discounted rate:$64USD/night
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Quality Inn O'Fallon IL - St. Louis
1409 W US 50,
O Fallon, IL, 62269, US
34.01 km from Clayton, MO, USA
3.56 stars rating. Good. 925 reviews3.56 stars rating. Good. 925 reviews
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Strikethrough Rate:~~$69~~Discounted rate:$59USD/night
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Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
32.92 km from Clayton, MO, USA
4.23 stars rating. Excellent. 1220 reviews4.23 stars rating. Excellent. 1220 reviews
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Strikethrough Rate:~~$105~~Discounted rate:$90USD/night
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Comfort Inn Edwardsville - St. Louis
3080 S. SR 157,
Edwardsville, IL, 62025, US
31.54 km from Clayton, MO, USA
4.17 stars rating. Very Good. 1365 reviews4.17 stars rating. Very Good. 1365 reviews
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Strikethrough Rate:~~$134~~Discounted rate:$121USD/night
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Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
33.28 km from Clayton, MO, USA
3.66 stars rating. Good. 856 reviews3.66 stars rating. Good. 856 reviews
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Strikethrough Rate:~~$89~~Discounted rate:$80USD/night
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Comfort Suites Fairview Heights - St Louis
137 Ludwig Drive,
Fairview Heights, IL, 62208, US
30.27 km from Clayton, MO, USA
3.46 stars rating. Good. 1776 reviews3.46 stars rating. Good. 1776 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$92USD/night
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Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive,
Fairview Heights, IL, 62208, US
30.29 km from Clayton, MO, USA
3.2 stars rating. Good. 219 reviews3.2 stars rating. Good. 219 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$89USD/night
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Econo Lodge Inn & Suites Fairview Heights - St. Louis
305 Salem Place,
Fairview Heights, IL, 62208, US
31.16 km from Clayton, MO, USA
3.74 stars rating. Good. 317 reviews3.74 stars rating. Good. 317 reviews
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Strikethrough Rate:~~$71~~Discounted rate:$63USD/night
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Comfort Inn & Suites St. Louis-O'Fallon
100 Comfort Inn Court,
O Fallon, MO, 63366, US
34.05 km from Clayton, MO, USA
3.68 stars rating. Good. 1867 reviews3.68 stars rating. Good. 1867 reviews
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Strikethrough Rate:~~$96~~Discounted rate:$87USD/night
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Comfort Inn Near Six Flags St. Louis
1320 Thornton St.,
Pacific, MO, 63069, US
40.77 km from Clayton, MO, USA
4.05 stars rating. Very Good. 1725 reviews4.05 stars rating. Very Good. 1725 reviews
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Strikethrough Rate:~~$108~~Discounted rate:$100USD/night
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Quality Inn Near Six Flags St. Louis
1400 West Osage St.,
Pacific, MO, 63069, US
40.91 km from Clayton, MO, USA
4 stars rating. Very Good. 655 reviews4 stars rating. Very Good. 655 reviews
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Strikethrough Rate:~~$106~~Discounted rate:$95USD/night
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Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy,
Fairview Heights, IL, 62208, US
31.21 km from Clayton, MO, USA
3.11 stars rating. Good. 133 reviews3.11 stars rating. Good. 133 reviews
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Strikethrough Rate:~~$104~~Discounted rate:$94USD/night
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Comfort Inn & Suites OFallon - St Louis Area
116 Regency Park,
O'Fallon, IL, 62269, US
35.18 km from Clayton, MO, USA
2.33 stars rating. Fair. 100 reviews2.33 stars rating. Fair. 100 reviews
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Strikethrough Rate:~~$89~~Discounted rate:$80USD/night
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The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
33.4 km from Clayton, MO, USA
2.84 stars rating. Fair. 92 reviews2.84 stars rating. Fair. 92 reviews
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Strikethrough Rate:~~$105~~Discounted rate:$100USD/night
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Good to know

Boutique hotels

35 hotels in Clayton

Highest Price

$165

Lowest Price

$48

Avg. rating

3.3 (35271 reviews)