34 Extended Stay hotels near Clayton, MO, USA

34 Extended Stay hotels near Clayton, MO, USA

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    • 38

      MainStay Suites St. Louis - Galleria

      1.19 mi from destination

      3.23 stars rating. Good. 165 reviews
      Save 16%
      Strikethrough Rate:$139Discounted rate:$116USD/night
      Member Rate
    • 27

      MainStay Suites St. Louis Airport

      7.12 mi from destination

      3.93 stars rating. Good. 234 reviews
      Save 16%
      Strikethrough Rate:$115Discounted rate:$96USD/night
      Member Rate
    Below are additional hotels in the area that do not match your exact search criteria.
    • 30

      Quality Inn Airport

      6.02 mi from destination

      3.27 stars rating. Good. 3022 reviews
      Save 7%
      Strikethrough Rate:$80Discounted rate:$74USD/night
      Member Rate
    • 35

      Comfort Inn & Suites

      6.64 mi from destination

      3.82 stars rating. Good. 92 reviews
      Save 7%
      Strikethrough Rate:$119Discounted rate:$111USD/night
      Member Rate
    • 40

      Comfort Inn St. Louis - Westport Event Center

      6.66 mi from destination

      3.57 stars rating. Good. 3077 reviews
      Save 12%
      Strikethrough Rate:$99Discounted rate:$87USD/night
      Member Rate
    • 30

      Comfort Inn St. Louis Airport

      7.1 mi from destination

      4.07 stars rating. Very Good. 175 reviews
      Save 16%
      Strikethrough Rate:$107Discounted rate:$90USD/night
      Member Rate
    • 33

      Comfort Suites St. Louis - Sunset Hills

      7.69 mi from destination

      4.71 stars rating. Exceptional. 1829 reviews
      Save 7%
      Strikethrough Rate:$114Discounted rate:$106USD/night
      Member Rate
    • 12

      Quality Inn Florissant-St. Louis

      8.71 mi from destination

      3.41 stars rating. Good. 1447 reviews
      Save 7%
      Strikethrough Rate:$75Discounted rate:$70USD/night
      Member Rate
    • 32

      Comfort Inn & Suites St. Louis-Hazelwood

      9 mi from destination

      4.12 stars rating. Very Good. 1975 reviews
      Save 12%
      Strikethrough Rate:$94Discounted rate:$83USD/night
      Member Rate
    • 11

      River City Casino & Hotel

      9.1 mi from destination

      No Reviews Yet
      $185USD/night
      Fees included
    • 25

      Hollywood Casino St Louis

      10.63 mi from destination

      No Reviews Yet
      Save 13%
      Strikethrough Rate:$125Discounted rate:$109USD/night
      Member Rate
      Fees included
    • 21

      Quality Inn & Suites near St. Louis and I-255

      11.37 mi from destination

      3.54 stars rating. Good. 1344 reviews
      Save 7%
      Strikethrough Rate:$86Discounted rate:$80USD/night
      Member Rate
    • 25

      Country Inn & Suites by Radisson, St. Charles Historic District

      11.65 mi from destination

      4.65 stars rating. Exceptional. 563 reviews
      Save 7%
      Strikethrough Rate:$169Discounted rate:$157USD/night
      Member Rate
    • 35

      Comfort Suites St Charles-St Louis

      11.71 mi from destination

      4.03 stars rating. Very Good. 2061 reviews
      Save 7%
      Strikethrough Rate:$119Discounted rate:$111USD/night
      Member Rate
    • 31

      Econo Lodge Inn & Suites

      13.96 mi from destination

      3.43 stars rating. Good. 373 reviews
      Save 7%
      Strikethrough Rate:$68Discounted rate:$63USD/night
      Member Rate
    • 42

      Country Inn & Suites by Radisson, St. Peters, MO

      15.65 mi from destination

      4.12 stars rating. Very Good. 207 reviews
      Save 7%
      Strikethrough Rate:$109Discounted rate:$101USD/night
      Member Rate
    • 29

      Sleep Inn

      15.67 mi from destination

      3.08 stars rating. 1020 reviews
      Save 7%
      Strikethrough Rate:$86Discounted rate:$80USD/night
      Member Rate
    • 31

      Quality Inn & Suites Caseyville - St. Louis

      15.9 mi from destination

      2.73 stars rating. Fair. 705 reviews
      Save 7%
      Strikethrough Rate:$76Discounted rate:$71USD/night
      Member Rate
    • 38

      Comfort Inn & Suites Chesterfield - St. Louis

      17.07 mi from destination

      3.92 stars rating. Good. 2439 reviews
      Save 14%
      Strikethrough Rate:$113Discounted rate:$97USD/night
      Member Rate
      Fees included
    • 36

      Comfort Inn Collinsville near St. Louis

      17.61 mi from destination

      4.19 stars rating. Very Good. 1914 reviews
      Save 19%
      Strikethrough Rate:$117Discounted rate:$95USD/night
      Member Rate
    • 30

      Comfort Suites Fairview Heights - St Louis

      18.81 mi from destination

      3.46 stars rating. Good. 1775 reviews
      Save 7%
      Strikethrough Rate:$99Discounted rate:$92USD/night
      Member Rate
    • 10

      Country Inn & Suites by Radisson, Fairview Heights, IL

      18.82 mi from destination

      3.19 stars rating. Good. 218 reviews
      Save 10%
      Strikethrough Rate:$100Discounted rate:$90USD/night
      Member Rate
    • 28

      Econo Lodge Inn & Suites Fairview Heights - St. Louis

      19.36 mi from destination

      3.74 stars rating. Good. 316 reviews
      Save 7%
      Strikethrough Rate:$71Discounted rate:$66USD/night
      Member Rate
    • 25

      Radisson Hotel Fairview Heights - St. Louis

      19.39 mi from destination

      3.12 stars rating. Good. 131 reviews
      Save 10%
      Strikethrough Rate:$104Discounted rate:$94USD/night
      Special Rate
    • 34

      Comfort Inn Edwardsville - St. Louis

      19.6 mi from destination

      4.17 stars rating. Very Good. 1364 reviews
      Save 10%
      Strikethrough Rate:$124Discounted rate:$112USD/night
      Member Rate
    • 28

      Sleep Inn & Suites O'Fallon MO - Technology Drive

      20.46 mi from destination

      4.23 stars rating. Excellent. 1216 reviews
      Save 14%
      Strikethrough Rate:$97Discounted rate:$83USD/night
      Member Rate
    • 41

      Comfort Inn Alton near I-255

      20.68 mi from destination

      3.66 stars rating. Good. 852 reviews
      Save 10%
      Strikethrough Rate:$89Discounted rate:$80USD/night
      Member Rate
    • 32

      The Great Rivers, an Ascend Collection Hotel

      20.75 mi from destination

      2.81 stars rating. Fair. 91 reviews
      Save 5%
      Strikethrough Rate:$110Discounted rate:$104USD/night
      Member Rate
    • 31

      Comfort Inn & Suites St. Louis-O'Fallon

      21.16 mi from destination

      3.68 stars rating. Good. 1862 reviews
      Save 10%
      Strikethrough Rate:$84Discounted rate:$75USD/night
      Member Rate
    • 26

      Quality Inn O'Fallon IL - St. Louis

      21.13 mi from destination

      3.56 stars rating. Good. 922 reviews
      Save 15%
      Strikethrough Rate:$70Discounted rate:$60USD/night
      Member Rate
    • 31

      Comfort Inn & Suites OFallon - St Louis Area

      21.86 mi from destination

      2.35 stars rating. Fair. 98 reviews
      Save 10%
      Strikethrough Rate:$89Discounted rate:$80USD/night
      Member Rate
    • 26

      Sleep Inn O'Fallon near I-64

      21.87 mi from destination

      3.39 stars rating. Good. 1322 reviews
      Save 12%
      Strikethrough Rate:$54Discounted rate:$48USD/night
      Member Rate
    • 35

      Comfort Inn Near Six Flags St. Louis

      25.33 mi from destination

      4.05 stars rating. Very Good. 1719 reviews
      Save 7%
      Strikethrough Rate:$120Discounted rate:$112USD/night
      Member Rate
    • 31

      Quality Inn Near Six Flags St. Louis

      25.42 mi from destination

      4 stars rating. Very Good. 653 reviews
      Save 10%
      Strikethrough Rate:$106Discounted rate:$95USD/night
      Member Rate
    Change your dates to book properties below.
    • 2

      Radisson Hotel St. Louis Downtown Convention Center

      7.9 mi from destination

      No Reviews Yet
      Coming soonStart booking Nov 12, 2025

    Other Clayton searches

    Good to know

    Extended stay hotels

    2 of 35 hotels in Clayton

    Highest Price

    $185

    Lowest Price

    $48

    Avg. rating

    3.3 (35181 reviews)

    Weekly Rate

    $336

    Monthly Rate

    $1,440