Book Boutique Hotels in Saint Charles, MO | Choice Hotels

AWARD WINNER
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
1.47 mi from St Charles, MO, USA
4.64 stars rating. Exceptional. 646 reviews4.64 stars rating. Exceptional. 646 reviews
Book Now & Save 7%
Strikethrough Rate:~~$124~~Discounted rate:$115USD/night
Member Rate
See Availability
Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
1.75 mi from St Charles, MO, USA
4.02 stars rating. Very Good. 2079 reviews4.02 stars rating. Very Good. 2079 reviews
Book Now & Save 7%
Strikethrough Rate:~~$114~~Discounted rate:$106USD/night
Member Rate
See Availability
Comfort Inn & Suites Hazelwood - St. Louis
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
5.66 mi from St Charles, MO, USA
4.11 stars rating. Very Good. 1988 reviews4.11 stars rating. Very Good. 1988 reviews
Book Now & Save 12%
Strikethrough Rate:~~$92~~Discounted rate:$82USD/night
Member Rate
See Availability
Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
5.86 mi from St Charles, MO, USA
4.08 stars rating. Very Good. 224 reviews4.08 stars rating. Very Good. 224 reviews
Book Now & Save 7%
Strikethrough Rate:~~$98~~Discounted rate:$91USD/night
Member Rate
See Availability
Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
3.71 mi from St Charles, MO, USA
4.05 stars rating. Very Good. 183 reviews4.05 stars rating. Very Good. 183 reviews
Book Now & Save 16%
Strikethrough Rate:~~$99~~Discounted rate:$83USD/night
Member Rate
See Availability
Sleep Inn Saint Charles North
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
5.3 mi from St Charles, MO, USA
3.09 stars rating. Fair. 1040 reviews3.09 stars rating. Fair. 1040 reviews
Book Now & Save 7%
Strikethrough Rate:~~$81~~Discounted rate:$75USD/night
Member Rate
See Availability
Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
12.2 mi from St Charles, MO, USA
3.91 stars rating. Good. 2482 reviews3.91 stars rating. Good. 2482 reviews
Book Now & Save 18%
Strikethrough Rate:~~$99~~Discounted rate:$81USD/night
Member Rate
Fees included
See Availability
Comfort Inn & Suites St. Louis-O'Fallon
8170 Veterans Memorial Pkwy,
O Fallon, MO, 63366, US
12.04 mi from St Charles, MO, USA
3.68 stars rating. Good. 1904 reviews3.68 stars rating. Good. 1904 reviews
Book Now & Save 7%
Strikethrough Rate:~~$85~~Discounted rate:$79USD/night
Member Rate
See Availability
Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
13.71 mi from St Charles, MO, USA
4.23 stars rating. Excellent. 1255 reviews4.23 stars rating. Excellent. 1255 reviews
Book Now & Save 15%
Strikethrough Rate:~~$86~~Discounted rate:$74USD/night
Member Rate
See Availability
Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
6.7 mi from St Charles, MO, USA
3.41 stars rating. Good. 1466 reviews3.41 stars rating. Good. 1466 reviews
Book Now & Save 7%
Strikethrough Rate:~~$74~~Discounted rate:$69USD/night
Member Rate
See Availability
Quality Inn Saint Louis Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
5.87 mi from St Charles, MO, USA
3.27 stars rating. Good. 3054 reviews3.27 stars rating. Good. 3054 reviews
Book Now & Save 7%
Strikethrough Rate:~~$84~~Discounted rate:$78USD/night
Member Rate
See Availability
AWARD WINNER
Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
15 mi from St Charles, MO, USA
4.72 stars rating. Exceptional. 1947 reviews4.72 stars rating. Exceptional. 1947 reviews
Book Now & Save 7%
Strikethrough Rate:~~$114~~Discounted rate:$106USD/night
Member Rate
See Availability
MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
3.7 mi from St Charles, MO, USA
3.9 stars rating. Good. 239 reviews3.9 stars rating. Good. 239 reviews
Book Now & Save 16%
Strikethrough Rate:~~$154~~Discounted rate:$129USD/night
Member Rate
See Availability
Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
20.04 mi from St Charles, MO, USA
3.66 stars rating. Good. 859 reviews3.66 stars rating. Good. 859 reviews
Book Now & Save 10%
Strikethrough Rate:~~$89~~Discounted rate:$80USD/night
Member Rate
See Availability
Comfort Suites Fairview Heights - St Louis
137 Ludwig Drive,
Fairview Heights, IL, 62208, US
27.54 mi from St Charles, MO, USA
3.46 stars rating. Good. 1802 reviews3.46 stars rating. Good. 1802 reviews
Book Now & Save 15%
Strikethrough Rate:~~$84~~Discounted rate:$72USD/night
Member Rate
See Availability
Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive,
Fairview Heights, IL, 62208, US
27.56 mi from St Charles, MO, USA
3.21 stars rating. Good. 223 reviews3.21 stars rating. Good. 223 reviews
Book Now & Save 10%
Strikethrough Rate:~~$101~~Discounted rate:$90USD/night
Member Rate
See Availability
MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
11.07 mi from St Charles, MO, USA
3.2 stars rating. Good. 190 reviews3.2 stars rating. Good. 190 reviews
Book Now & Save 7%
Strikethrough Rate:~~$124~~Discounted rate:$115USD/night
Member Rate
See Availability
Comfort Inn Collinsville near St. Louis
8 Commerce Dr.,
Collinsville, IL, 62234, US
24.7 mi from St Charles, MO, USA
4.2 stars rating. Excellent. 1954 reviews4.2 stars rating. Excellent. 1954 reviews
Book Now & Save 19%
Strikethrough Rate:~~$118~~Discounted rate:$96USD/night
Special Rate
See Availability
Quality Inn Foristell
12 Highway W,
Foristell, MO, 63348, US
26.78 mi from St Charles, MO, USA
4.21 stars rating. Excellent. 926 reviews4.21 stars rating. Excellent. 926 reviews
Book Now & Save 19%
Strikethrough Rate:~~$88~~Discounted rate:$71USD/night
Member Rate
See Availability
Comfort Inn & Suites Saint Louis Lafayette Square
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
16.49 mi from St Charles, MO, USA
3.79 stars rating. Good. 114 reviews3.79 stars rating. Good. 114 reviews
Book Now & Save 7%
Strikethrough Rate:~~$139~~Discounted rate:$129USD/night
Member Rate
See Availability
Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
21.54 mi from St Charles, MO, USA
3.54 stars rating. Good. 1347 reviews3.54 stars rating. Good. 1347 reviews
Book Now & Save 16%
Strikethrough Rate:~~$82~~Discounted rate:$68USD/night
Member Rate
See Availability
Econo Lodge Inn & Suites Granite City - St. Louis
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
18.21 mi from St Charles, MO, USA
3.44 stars rating. Good. 386 reviews3.44 stars rating. Good. 386 reviews
Book Now & Save 7%
Strikethrough Rate:~~$69~~Discounted rate:$64USD/night
Member Rate
See Availability
Econo Lodge Inn & Suites Fairview Heights - St. Louis
305 Salem Place,
Fairview Heights, IL, 62208, US
28.04 mi from St Charles, MO, USA
3.74 stars rating. Good. 318 reviews3.74 stars rating. Good. 318 reviews
Book Now & Save 12%
Strikethrough Rate:~~$71~~Discounted rate:$63USD/night
Member Rate
See Availability
Comfort Inn Edwardsville - St. Louis
3080 S. SR 157,
Edwardsville, IL, 62025, US
24.5 mi from St Charles, MO, USA
4.16 stars rating. Very Good. 1370 reviews4.16 stars rating. Very Good. 1370 reviews
Book Now & Save 10%
Strikethrough Rate:~~$145~~Discounted rate:$131USD/night
Member Rate
See Availability
Quality Inn Pacific near Six Flags St. Louis
1400 West Osage St.,
Pacific, MO, 63069, US
25.21 mi from St Charles, MO, USA
4 stars rating. Very Good. 657 reviews4 stars rating. Very Good. 657 reviews
Book Now & Save 10%
Strikethrough Rate:~~$99~~Discounted rate:$89USD/night
Member Rate
See Availability
Quality Inn & Suites Caseyville - St. Louis
2180 Patricia Dr.,
Caseyville, IL, 62232, US
24.67 mi from St Charles, MO, USA
2.72 stars rating. Fair. 710 reviews2.72 stars rating. Fair. 710 reviews
Book Now & Save 7%
Strikethrough Rate:~~$69~~Discounted rate:$64USD/night
Member Rate
See Availability
Comfort Inn Near Six Flags St. Louis
1320 Thornton St.,
Pacific, MO, 63069, US
25.09 mi from St Charles, MO, USA
4.06 stars rating. Very Good. 1764 reviews4.06 stars rating. Very Good. 1764 reviews
Book Now & Save 7%
Strikethrough Rate:~~$109~~Discounted rate:$102USD/night
Member Rate
See Availability
River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
19.33 mi from St Charles, MO, USA
No Reviews YetNo Reviews Yet
$204USD/night
Fees included
See Availability
NEW TO CHOICE
Radisson Hotel St. Louis Downtown Convention Center
811 N 9th St,
St. Louis, MO, 63101, US
17.08 mi from St Charles, MO, USA
1.52 stars rating. Fair. 44 reviews1.52 stars rating. Fair. 44 reviews
Book Now & Save 5%
Strikethrough Rate:~~$190~~Discounted rate:$181USD/night
Member Rate
See Availability
The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
20.11 mi from St Charles, MO, USA
2.87 stars rating. Fair. 102 reviews2.87 stars rating. Fair. 102 reviews
Book Now & Save 5%
Strikethrough Rate:~~$104~~Discounted rate:$99USD/night
Member Rate
See Availability
Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy,
Fairview Heights, IL, 62208, US
28.03 mi from St Charles, MO, USA
3.44 stars rating. Good. 178 reviews3.44 stars rating. Good. 178 reviews
Book Now & Save 5%
Strikethrough Rate:~~$119~~Discounted rate:$113USD/night
Member Rate
See Availability

Change your dates to book properties below.

Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd.,
Saint Louis, MO, 63146, US
4.74 mi from St Charles, MO, USA
3.55 stars rating. Good. 3113 reviews3.55 stars rating. Good. 3113 reviews
Sold outfor your selected dates
See Availability
Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
1.46 mi from St Charles, MO, USA
No Reviews YetNo Reviews Yet
Sold outfor your selected dates
See Availability

Other Saint Charles searches

All Hotels in Saint Charles

Hotel Deals in Saint Charles

Extended Stay Hotels in Saint Charles

Pet Friendly Hotels in Saint Charles

Top Rated Hotels in Saint Charles

Good to know

Boutique hotels

31 of 33 hotels in Saint Charles

Highest Price

$204

Lowest Price

$63

Avg. rating

3.5 (34564 reviews)