Ascend Collection Hotels in South Carolina

South Carolina is known for its historic sites, charming attractions and Southern Hospitality. From the beaches of the coast to the majestic peaks of the Blue Ridge Mountains, there is plenty to see and do in the Palmetto State. By booking a room at one of our Ascend Hotel Collection South Carolina hotels, you can enjoy the places, moments and things that make each trip special. Stroll down the beach and boardwalk to enjoy sun and fun in Myrtle Beach. Experience the excitement of a NASCAR race at Darlington Raceway. Hike along the Foothills Trail in the Upstate region and make a stop to view the breathtaking Lower Whitewater Falls. Our South Carolina hotels provide relaxing accommodations near many popular attractions. The Ascend Hotel Collection is a network of one-of-a-kind upscale properties that embody the distinct character and local flavor of each destination while ensuring that guests receive the same high level of service and luxury at each and every hotel. Choose from one of our South Carolina hotels below and let the destination reach you.