Hotels in Defiance, MO – Choice Hotels

Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
11.25 km from Defiance, MO 63341, USA
4.24 stars rating. Excellent. 1252 reviews4.24 stars rating. Excellent. 1252 reviews
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Strikethrough Rate:~~$101~~Discounted rate:$86USD/night
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Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
11.83 km from Defiance, MO 63341, USA
3.91 stars rating. Good. 2475 reviews3.91 stars rating. Good. 2475 reviews
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Strikethrough Rate:~~$117~~Discounted rate:$95USD/night
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Comfort Inn & Suites St. Louis-O'Fallon
8170 Veterans Memorial Pkwy,
O Fallon, MO, 63366, US
20.55 km from Defiance, MO 63341, USA
3.68 stars rating. Good. 1899 reviews3.68 stars rating. Good. 1899 reviews
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Strikethrough Rate:~~$81~~Discounted rate:$73USD/night
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Quality Inn Pacific near Six Flags St. Louis
1400 West Osage St.,
Pacific, MO, 63069, US
16.61 km from Defiance, MO 63341, USA
4 stars rating. Very Good. 657 reviews4 stars rating. Very Good. 657 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$107USD/night
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Quality Inn Foristell
12 Highway W,
Foristell, MO, 63348, US
25.61 km from Defiance, MO 63341, USA
4.21 stars rating. Excellent. 926 reviews4.21 stars rating. Excellent. 926 reviews
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Strikethrough Rate:~~$87~~Discounted rate:$70USD/night
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Comfort Inn Near Six Flags St. Louis
1320 Thornton St.,
Pacific, MO, 63069, US
16.41 km from Defiance, MO 63341, USA
4.06 stars rating. Very Good. 1758 reviews4.06 stars rating. Very Good. 1758 reviews
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Strikethrough Rate:~~$134~~Discounted rate:$127USD/night
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Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
25.76 km from Defiance, MO 63341, USA
4.1 stars rating. Very Good. 221 reviews4.1 stars rating. Very Good. 221 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$94USD/night
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Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
29.13 km from Defiance, MO 63341, USA
4.02 stars rating. Very Good. 2079 reviews4.02 stars rating. Very Good. 2079 reviews
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Strikethrough Rate:~~$104~~Discounted rate:$99USD/night
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Comfort Inn & Suites Hazelwood - St. Louis
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
40.14 km from Defiance, MO 63341, USA
4.11 stars rating. Very Good. 1988 reviews4.11 stars rating. Very Good. 1988 reviews
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Strikethrough Rate:~~$104~~Discounted rate:$94USD/night
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AWARD WINNER
Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
33.56 km from Defiance, MO 63341, USA
4.72 stars rating. Exceptional. 1938 reviews4.72 stars rating. Exceptional. 1938 reviews
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Strikethrough Rate:~~$129~~Discounted rate:$123USD/night
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AWARD WINNER
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
29.78 km from Defiance, MO 63341, USA
4.65 stars rating. Exceptional. 640 reviews4.65 stars rating. Exceptional. 640 reviews
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Strikethrough Rate:~~$149~~Discounted rate:$142USD/night
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Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
35.11 km from Defiance, MO 63341, USA
4.05 stars rating. Very Good. 183 reviews4.05 stars rating. Very Good. 183 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$93USD/night
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Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd.,
Saint Louis, MO, 63146, US
29.95 km from Defiance, MO 63341, USA
3.56 stars rating. Good. 3111 reviews3.56 stars rating. Good. 3111 reviews
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Strikethrough Rate:~~$110~~Discounted rate:$99USD/night
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Sleep Inn Saint Charles North
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
31.12 km from Defiance, MO 63341, USA
3.08 stars rating. Fair. 1038 reviews3.08 stars rating. Fair. 1038 reviews
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Strikethrough Rate:~~$82~~Discounted rate:$78USD/night
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MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
35.12 km from Defiance, MO 63341, USA
3.9 stars rating. Good. 239 reviews3.9 stars rating. Good. 239 reviews
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Strikethrough Rate:~~$107~~Discounted rate:$91USD/night
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Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
41.6 km from Defiance, MO 63341, USA
3.41 stars rating. Good. 1460 reviews3.41 stars rating. Good. 1460 reviews
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Strikethrough Rate:~~$74~~Discounted rate:$70USD/night
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Quality Inn Saint Louis Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
38.28 km from Defiance, MO 63341, USA
3.27 stars rating. Good. 3048 reviews3.27 stars rating. Good. 3048 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$81USD/night
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MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
37.77 km from Defiance, MO 63341, USA
3.22 stars rating. Good. 187 reviews3.22 stars rating. Good. 187 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$113USD/night
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Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
29.04 km from Defiance, MO 63341, USA
No Reviews YetNo Reviews Yet
$215USD/night
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River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
46.14 km from Defiance, MO 63341, USA
No Reviews YetNo Reviews Yet
$245USD/night
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Good to know

Number of hotels

20 hotels in Defiance

Highest Price

$245

Lowest Price

$70

Avg. rating

20 hotels near Defiance, MO 63341, USA

Sleep Inn & Suites O'Fallon MO - Technology Drive

Comfort Inn & Suites Chesterfield - St. Louis

Comfort Inn & Suites St. Louis-O'Fallon

Quality Inn Pacific near Six Flags St. Louis

Quality Inn Foristell

Comfort Inn Near Six Flags St. Louis

Country Inn & Suites by Radisson, St. Peters, MO

Comfort Suites St Charles-St Louis

Comfort Inn & Suites Hazelwood - St. Louis

Comfort Suites St. Louis - Sunset Hills

Country Inn & Suites by Radisson, St. Charles Historic District

Comfort Inn St. Louis Airport

Comfort Inn St. Louis - Westport Event Center

Sleep Inn Saint Charles North

MainStay Suites St. Louis Airport

Quality Inn Florissant-St. Louis

Quality Inn Saint Louis Airport

MainStay Suites St. Louis - Galleria

Hollywood Casino St Louis

River City Casino & Hotel

Other Defiance searches

Good to know

20 hotels in Defiance

$245

$70

3.5 (25099 reviews)