Extended Stay Hotels in Saint Charles, MO

WoodSpring Suites St Louis St Charles
2100 Old Hwy 94 S.,
Saint Charles, MO, 63303, US
3.23 mi from Saint Charles, MO
3.22 stars rating. Good. 35 reviews3.22 stars rating. Good. 35 reviews
$76USD/night
See Availability
MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
5.33 mi from Saint Charles, MO
3.93 stars rating. Good. 233 reviews3.93 stars rating. Good. 233 reviews
BOOK NOW AND SAVE 16%
Strikethrough Rate:~~$116~~Discounted rate:$97USD/night
Member Rate
See Availability
MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
12.74 mi from Saint Charles, MO
3.25 stars rating. Good. 154 reviews3.25 stars rating. Good. 154 reviews
BOOK NOW AND SAVE 16%
Strikethrough Rate:~~$169~~Discounted rate:$141USD/night
Member Rate
See Availability
WoodSpring Suites St Louis Arnold
888 Arnold Commons Dr.,
Arnold, MO, 63010, US
24.59 mi from Saint Charles, MO
3.33 stars rating. Good. 36 reviews3.33 stars rating. Good. 36 reviews
$81USD/night
See Availability

Below are additional hotels in the area that do not match your exact search criteria.

Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
1.14 mi from Saint Charles, MO
4.03 stars rating. Very Good. 2023 reviews4.03 stars rating. Very Good. 2023 reviews
BOOK NOW AND SAVE 12%
Strikethrough Rate:~~$119~~Discounted rate:$105USD/night
Member Rate
See Availability
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
0.8 mi from Saint Charles, MO
4.64 stars rating. Exceptional. 477 reviews4.64 stars rating. Exceptional. 477 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$184~~Discounted rate:$171USD/night
Member Rate
See Availability
Comfort Inn & Suites St. Louis-Hazelwood
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
6.76 mi from Saint Charles, MO
4.13 stars rating. Very Good. 1955 reviews4.13 stars rating. Very Good. 1955 reviews
BOOK NOW AND SAVE 15%
Strikethrough Rate:~~$95~~Discounted rate:$81USD/night
Member Rate
See Availability
Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
4.43 mi from Saint Charles, MO
4.13 stars rating. Very Good. 177 reviews4.13 stars rating. Very Good. 177 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$109~~Discounted rate:$101USD/night
Member Rate
See Availability
Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
5.34 mi from Saint Charles, MO
4.11 stars rating. Very Good. 160 reviews4.11 stars rating. Very Good. 160 reviews
BOOK NOW AND SAVE 16%
Strikethrough Rate:~~$105~~Discounted rate:$88USD/night
Member Rate
See Availability
Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
2.03 mi from Saint Charles, MO
No Reviews YetNo Reviews Yet
BOOK NOW AND SAVE 14%
Strikethrough Rate:~~$155~~Discounted rate:$134USD/night
Member Rate
Fees included
See Availability
Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd.,
Saint Louis, MO, 63146, US
6.22 mi from Saint Charles, MO
3.59 stars rating. Good. 3032 reviews3.59 stars rating. Good. 3032 reviews
BOOK NOW AND SAVE 12%
Strikethrough Rate:~~$99~~Discounted rate:$87USD/night
Member Rate
See Availability
Sleep Inn
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
3.62 mi from Saint Charles, MO
3.09 stars rating. 1011 reviews3.09 stars rating. 1011 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$86~~Discounted rate:$80USD/night
Member Rate
See Availability
Comfort Inn & Suites St. Louis-O'Fallon
100 Comfort Inn Court,
O Fallon, MO, 63366, US
10.68 mi from Saint Charles, MO
3.7 stars rating. Good. 1824 reviews3.7 stars rating. Good. 1824 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$90~~Discounted rate:$83USD/night
Member Rate
See Availability
Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
7.85 mi from Saint Charles, MO
3.43 stars rating. Good. 1429 reviews3.43 stars rating. Good. 1429 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$84~~Discounted rate:$78USD/night
Member Rate
See Availability
Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
11.95 mi from Saint Charles, MO
3.93 stars rating. Good. 2415 reviews3.93 stars rating. Good. 2415 reviews
BOOK NOW AND SAVE 14%
Strikethrough Rate:~~$113~~Discounted rate:$97USD/night
Member Rate
Fees included
See Availability
Quality Inn Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
7.43 mi from Saint Charles, MO
3.28 stars rating. Good. 2994 reviews3.28 stars rating. Good. 2994 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$84~~Discounted rate:$78USD/night
Member Rate
See Availability
Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
12.95 mi from Saint Charles, MO
4.23 stars rating. Excellent. 1194 reviews4.23 stars rating. Excellent. 1194 reviews
BOOK NOW AND SAVE 15%
Strikethrough Rate:~~$102~~Discounted rate:$88USD/night
Member Rate
See Availability
Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
16.45 mi from Saint Charles, MO
4.71 stars rating. Exceptional. 1727 reviews4.71 stars rating. Exceptional. 1727 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$114~~Discounted rate:$106USD/night
Member Rate
See Availability
Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
20.56 mi from Saint Charles, MO
3.69 stars rating. Good. 834 reviews3.69 stars rating. Good. 834 reviews
BOOK NOW AND SAVE 10%
Strikethrough Rate:~~$96~~Discounted rate:$86USD/night
Member Rate
See Availability
Comfort Inn & Suites
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
18.17 mi from Saint Charles, MO
3.8 stars rating. Good. 79 reviews3.8 stars rating. Good. 79 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$116~~Discounted rate:$108USD/night
Member Rate
See Availability
Econo Lodge Inn & Suites
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
19.44 mi from Saint Charles, MO
3.44 stars rating. Good. 366 reviews3.44 stars rating. Good. 366 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$69~~Discounted rate:$64USD/night
Member Rate
See Availability
Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
23.23 mi from Saint Charles, MO
3.54 stars rating. Good. 1330 reviews3.54 stars rating. Good. 1330 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$84~~Discounted rate:$78USD/night
Member Rate
See Availability
River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
20.99 mi from Saint Charles, MO
No Reviews YetNo Reviews Yet
$165USD/night
Fees included
See Availability
The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
20.63 mi from Saint Charles, MO
2.72 stars rating. Fair. 75 reviews2.72 stars rating. Fair. 75 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$108~~Discounted rate:$103USD/night
Member Rate
See Availability

Change your dates to book properties below.

WoodSpring Suites St Peters-OFallon
7850 Veterans Memorial Parkway,
St. Peters, MO, 63376, US
9.59 mi from Saint Charles, MO
No Reviews YetNo Reviews Yet
Coming soonStart booking Sep 30, 2025
See Availability

Good to know

Extended stay hotels

5 of 25 hotels in Saint Charles

Highest Price

$171

Lowest Price

$64

Avg. rating

3.3 (23560 reviews)

Weekly Rate

$448

Monthly Rate

4 Extended Stay hotels near Saint Charles, MO match your filters

WoodSpring Suites St Louis St Charles

MainStay Suites St. Louis Airport

MainStay Suites St. Louis - Galleria

WoodSpring Suites St Louis Arnold

Below are additional hotels in the area that do not match your exact search criteria.

Comfort Suites St Charles-St Louis

Country Inn & Suites by Radisson, St. Charles Historic District

Comfort Inn & Suites St. Louis-Hazelwood

Country Inn & Suites by Radisson, St. Peters, MO

Comfort Inn St. Louis Airport

Hollywood Casino St Louis

Comfort Inn St. Louis - Westport Event Center

Sleep Inn

Comfort Inn & Suites St. Louis-O'Fallon

Quality Inn Florissant-St. Louis

Comfort Inn & Suites Chesterfield - St. Louis

Quality Inn Airport

Sleep Inn & Suites O'Fallon MO - Technology Drive

Comfort Suites St. Louis - Sunset Hills

Comfort Inn Alton near I-255

Comfort Inn & Suites

Econo Lodge Inn & Suites

Quality Inn & Suites near St. Louis and I-255

River City Casino & Hotel

The Great Rivers, an Ascend Collection Hotel

Change your dates to book properties below.

WoodSpring Suites St Peters-OFallon

Other Saint Charles searches

Good to know

5 of 25 hotels in Saint Charles

$171

$64

3.3 (23560 reviews)

$448

$1,920