Book Top Rated Hotels in Saint Charles, MO

Change your dates to book properties below.

Comfort Suites Fairview Heights - St Louis
137 Ludwig Drive,
Fairview Heights, IL, 62208, US
46.86 km from St Charles, MO, USA
3.46 stars rating. Good. 1776 reviews3.46 stars rating. Good. 1776 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites St. Louis-Hazelwood
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
10.88 km from St Charles, MO, USA
4.12 stars rating. Very Good. 1977 reviews4.12 stars rating. Very Good. 1977 reviews
Sold outfor your selected dates
See Availability
Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
20.84 km from St Charles, MO, USA
4.23 stars rating. Excellent. 1220 reviews4.23 stars rating. Excellent. 1220 reviews
Sold outfor your selected dates
See Availability
Quality Inn & Suites Caseyville - St. Louis
2180 Patricia Dr.,
Caseyville, IL, 62232, US
42.27 km from St Charles, MO, USA
2.73 stars rating. Fair. 706 reviews2.73 stars rating. Fair. 706 reviews
Sold outfor your selected dates
See Availability
Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
1.84 km from St Charles, MO, USA
4.02 stars rating. Very Good. 2071 reviews4.02 stars rating. Very Good. 2071 reviews
Sold outfor your selected dates
See Availability
Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
8.6 km from St Charles, MO, USA
4.07 stars rating. Very Good. 178 reviews4.07 stars rating. Very Good. 178 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites St. Louis-O'Fallon
100 Comfort Inn Court,
O Fallon, MO, 63366, US
17.19 km from St Charles, MO, USA
3.68 stars rating. Good. 1867 reviews3.68 stars rating. Good. 1867 reviews
Sold outfor your selected dates
See Availability
Quality Inn Near Six Flags St. Louis
1400 West Osage St.,
Pacific, MO, 63069, US
40.96 km from St Charles, MO, USA
4 stars rating. Very Good. 655 reviews4 stars rating. Very Good. 655 reviews
Sold outfor your selected dates
See Availability
Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
3.27 km from St Charles, MO, USA
No Reviews YetNo Reviews Yet
Sold outfor your selected dates
See Availability
Comfort Inn & Suites
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
29.25 km from St Charles, MO, USA
3.81 stars rating. Good. 93 reviews3.81 stars rating. Good. 93 reviews
Sold outfor your selected dates
See Availability
Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
12.64 km from St Charles, MO, USA
3.41 stars rating. Good. 1451 reviews3.41 stars rating. Good. 1451 reviews
Sold outfor your selected dates
See Availability
Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
33.09 km from St Charles, MO, USA
3.66 stars rating. Good. 856 reviews3.66 stars rating. Good. 856 reviews
Sold outfor your selected dates
See Availability
Econo Lodge Inn & Suites Fairview Heights - St. Louis
305 Salem Place,
Fairview Heights, IL, 62208, US
47.66 km from St Charles, MO, USA
3.74 stars rating. Good. 317 reviews3.74 stars rating. Good. 317 reviews
Sold outfor your selected dates
See Availability
Radisson Hotel St. Louis Downtown Convention Center
811 N 9th St,
St. Louis, MO, 63101, US
30.14 km from St Charles, MO, USA
No Reviews YetNo Reviews Yet
Sold outfor your selected dates
See Availability
River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
33.79 km from St Charles, MO, USA
No Reviews YetNo Reviews Yet
Sold outfor your selected dates
See Availability
Comfort Inn Near Six Flags St. Louis
1320 Thornton St.,
Pacific, MO, 63069, US
40.77 km from St Charles, MO, USA
4.05 stars rating. Very Good. 1725 reviews4.05 stars rating. Very Good. 1725 reviews
Sold outfor your selected dates
See Availability
Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
26.48 km from St Charles, MO, USA
4.71 stars rating. Exceptional. 1840 reviews4.71 stars rating. Exceptional. 1840 reviews
Sold outfor your selected dates
See Availability
Comfort Inn Edwardsville - St. Louis
3080 S. SR 157,
Edwardsville, IL, 62025, US
41.37 km from St Charles, MO, USA
4.17 stars rating. Very Good. 1365 reviews4.17 stars rating. Very Good. 1365 reviews
Sold outfor your selected dates
See Availability
Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive,
Fairview Heights, IL, 62208, US
46.89 km from St Charles, MO, USA
3.2 stars rating. Good. 219 reviews3.2 stars rating. Good. 219 reviews
Sold outfor your selected dates
See Availability
Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy,
Fairview Heights, IL, 62208, US
47.64 km from St Charles, MO, USA
3.11 stars rating. Good. 133 reviews3.11 stars rating. Good. 133 reviews
Sold outfor your selected dates
See Availability
Econo Lodge Inn & Suites
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
31.29 km from St Charles, MO, USA
3.43 stars rating. Good. 373 reviews3.43 stars rating. Good. 373 reviews
Sold outfor your selected dates
See Availability
Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
37.38 km from St Charles, MO, USA
3.54 stars rating. Good. 1344 reviews3.54 stars rating. Good. 1344 reviews
Sold outfor your selected dates
See Availability
Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
19.24 km from St Charles, MO, USA
3.92 stars rating. Good. 2443 reviews3.92 stars rating. Good. 2443 reviews
Sold outfor your selected dates
See Availability
MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
8.58 km from St Charles, MO, USA
3.93 stars rating. Good. 234 reviews3.93 stars rating. Good. 234 reviews
Sold outfor your selected dates
See Availability
MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
20.5 km from St Charles, MO, USA
3.22 stars rating. Good. 166 reviews3.22 stars rating. Good. 166 reviews
Sold outfor your selected dates
See Availability
Quality Inn
12 Highway W,
Foristell, MO, 63348, US
40.97 km from St Charles, MO, USA
4.22 stars rating. Excellent. 923 reviews4.22 stars rating. Excellent. 923 reviews
Sold outfor your selected dates
See Availability
Quality Inn Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
11.96 km from St Charles, MO, USA
3.27 stars rating. Good. 3026 reviews3.27 stars rating. Good. 3026 reviews
Sold outfor your selected dates
See Availability
Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
7.13 km from St Charles, MO, USA
4.12 stars rating. Very Good. 208 reviews4.12 stars rating. Very Good. 208 reviews
Sold outfor your selected dates
See Availability
Sleep Inn
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
5.82 km from St Charles, MO, USA
3.08 stars rating. 1021 reviews3.08 stars rating. 1021 reviews
Sold outfor your selected dates
See Availability
The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
33.19 km from St Charles, MO, USA
2.84 stars rating. Fair. 92 reviews2.84 stars rating. Fair. 92 reviews
Sold outfor your selected dates
See Availability
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
1.28 km from St Charles, MO, USA
4.65 stars rating. Exceptional. 571 reviews4.65 stars rating. Exceptional. 571 reviews
Sold outfor your selected dates
See Availability
Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd.,
Saint Louis, MO, 63146, US
10.01 km from St Charles, MO, USA
3.57 stars rating. Good. 3079 reviews3.57 stars rating. Good. 3079 reviews
Sold outfor your selected dates
See Availability
Comfort Inn Collinsville near St. Louis
8 Commerce Dr.,
Collinsville, IL, 62234, US
42.06 km from St Charles, MO, USA
4.19 stars rating. Very Good. 1919 reviews4.19 stars rating. Very Good. 1919 reviews
Sold outfor your selected dates
See Availability

Good to know

Top-Rated hotels

33 hotels in Saint Charles

Avg. rating

0 Top Rated hotels near St Charles, MO, USA

Change your dates to book properties below.

Comfort Suites Fairview Heights - St Louis

Comfort Inn & Suites St. Louis-Hazelwood

Sleep Inn & Suites O'Fallon MO - Technology Drive

Quality Inn & Suites Caseyville - St. Louis

Comfort Suites St Charles-St Louis

Comfort Inn St. Louis Airport

Comfort Inn & Suites St. Louis-O'Fallon

Quality Inn Near Six Flags St. Louis

Hollywood Casino St Louis

Comfort Inn & Suites

Quality Inn Florissant-St. Louis

Comfort Inn Alton near I-255

Econo Lodge Inn & Suites Fairview Heights - St. Louis

Radisson Hotel St. Louis Downtown Convention Center

River City Casino & Hotel

Comfort Inn Near Six Flags St. Louis

Comfort Suites St. Louis - Sunset Hills

Comfort Inn Edwardsville - St. Louis

Country Inn & Suites by Radisson, Fairview Heights, IL

Radisson Hotel Fairview Heights - St. Louis

Econo Lodge Inn & Suites

Quality Inn & Suites near St. Louis and I-255

Comfort Inn & Suites Chesterfield - St. Louis

MainStay Suites St. Louis Airport

MainStay Suites St. Louis - Galleria

Quality Inn

Quality Inn Airport

Country Inn & Suites by Radisson, St. Peters, MO

Sleep Inn

The Great Rivers, an Ascend Collection Hotel

Country Inn & Suites by Radisson, St. Charles Historic District

Comfort Inn St. Louis - Westport Event Center

Comfort Inn Collinsville near St. Louis

Other Saint Charles searches

Good to know

33 hotels in Saint Charles

3.4 (33848 reviews)