Extended Stay Hotels in Florence, SC - Choice Hotels

MainStay Suites
1819 West Lucas Street, Building B,
Florence, SC, 29501, US
4.48 km from Florence, SC
1.95 stars rating. Fair. 57 reviews1.95 stars rating. Fair. 57 reviews
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Strikethrough Rate:~~$72~~Discounted rate:$67USD/night
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Suburban Studios Florence - Darlington
1914 West Lucas Street, I-95 & US 52,
Florence, SC, 29501, US
4.57 km from Florence, SC
2.92 stars rating. Fair. 1323 reviews2.92 stars rating. Fair. 1323 reviews
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Strikethrough Rate:~~$55~~Discounted rate:$51USD/night
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Below are additional hotels in the area that do not match your exact search criteria.

Clarion Inn & Suites
1819 West Lucas Street, Building A,
Florence, SC, 29501, US
4.43 km from Florence, SC
1.91 stars rating. Fair. 193 reviews1.91 stars rating. Fair. 193 reviews
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Strikethrough Rate:~~$63~~Discounted rate:$60USD/night
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Econo Lodge
1920 West Lucas Street,
Florence, SC, 29501, US
4.6 km from Florence, SC
2.87 stars rating. Fair. 1356 reviews2.87 stars rating. Fair. 1356 reviews
BOOK NOW AND SAVE 12%
Strikethrough Rate:~~$63~~Discounted rate:$56USD/night
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Park Inn by Radisson Florence, SC
1729 Mandeville Road,
Florence, SC, 29501, US
4.93 km from Florence, SC
4.28 stars rating. Excellent. 332 reviews4.28 stars rating. Excellent. 332 reviews
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Strikethrough Rate:~~$111~~Discounted rate:$105USD/night
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Sleep Inn Florence North
1833 Florence Park Dr., I-95 & US 52,
Florence, SC, 29501, US
5.32 km from Florence, SC
3.74 stars rating. Good. 1974 reviews3.74 stars rating. Good. 1974 reviews
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Strikethrough Rate:~~$80~~Discounted rate:$74USD/night
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Comfort Suites Florence I-95
2120 West Lucas Street,
Florence, SC, 29501, US
5.34 km from Florence, SC
4.27 stars rating. Excellent. 2605 reviews4.27 stars rating. Excellent. 2605 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$113USD/night
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Comfort Inn & Suites
527 Woody Jones Blvd.,
Florence, SC, 29501, US
6.28 km from Florence, SC
4.5 stars rating. Excellent. 1169 reviews4.5 stars rating. Excellent. 1169 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$113USD/night
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Quality Inn & Suites Florence Civic Center
150 Dunbarton Drive,
Florence, SC, 29501, US
6.82 km from Florence, SC
3.95 stars rating. Good. 1741 reviews3.95 stars rating. Good. 1741 reviews
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Strikethrough Rate:~~$108~~Discounted rate:$100USD/night
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Quality Inn
903 South Fifth Street,
Hartsville, SC, 29550, US
33.19 km from Florence, SC
2.94 stars rating. Fair. 392 reviews2.94 stars rating. Fair. 392 reviews
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Strikethrough Rate:~~$78~~Discounted rate:$72USD/night
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Quality Inn & Suites
202 North Ron McNair Blvd.,
Lake City, SC, 29560, US
35.49 km from Florence, SC
3.34 stars rating. Good. 98 reviews3.34 stars rating. Good. 98 reviews
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Strikethrough Rate:~~$143~~Discounted rate:$133USD/night
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Rodeway Inn
415 S. Irby St.,
Florence, SC, 29501, US
0.75 km from Florence, SC
No Reviews YetNo Reviews Yet
Coming soonStart booking Sep 30, 2025
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Good to know

Extended stay hotels

2 of 12 hotels in Florence

Highest Price

$133

Lowest Price

$51

Avg. rating

3.1 (11240 reviews)

Weekly Rate

$357

Monthly Rate

$1,530