Comfort Inn Edwardsville - St. Louis
3080 S. SR 157,
Edwardsville, IL, 62025, US
4.16 stars rating. Very Good. 1391 reviews
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Strikethrough Rate:~~$120~~Discounted rate:$108USD/night
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Comfort Inn Collinsville near St. Louis
8 Commerce Dr.,
Collinsville, IL, 62234, US
4.2 stars rating. Excellent. 1991 reviews
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Strikethrough Rate:~~$153~~Discounted rate:$128USD/night
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Comfort Suites Fairview Heights - St Louis
137 Ludwig Drive,
Fairview Heights, IL, 62208, US
3.44 stars rating. Good. 1831 reviews
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Strikethrough Rate:~~$79~~Discounted rate:$71USD/night
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Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
3.64 stars rating. Good. 872 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$98USD/night
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Quality Inn O'Fallon IL - St. Louis
1409 W US 50,
O Fallon, IL, 62269, US
3.54 stars rating. Good. 963 reviews
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Strikethrough Rate:~~$75~~Discounted rate:$71USD/night
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Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive,
Fairview Heights, IL, 62208, US
3.17 stars rating. Good. 246 reviews
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Strikethrough Rate:~~$92~~Discounted rate:$83USD/night
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Econo Lodge Inn & Suites Granite City - St. Louis
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
3.46 stars rating. Good. 397 reviews
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Strikethrough Rate:~~$69~~Discounted rate:$64USD/night
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The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
2.91 stars rating. Fair. 115 reviews
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Strikethrough Rate:~~$138~~Discounted rate:$132USD/night
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Sleep Inn O'Fallon near I-64
140 Venita Drive,
O Fallon, IL, 62269, US
3.36 stars rating. Good. 1359 reviews
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Strikethrough Rate:~~$79~~Discounted rate:$73USD/night
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Quality Inn & Suites Caseyville - St. Louis
2180 Patricia Dr.,
Caseyville, IL, 62232, US
2.7 stars rating. Fair. 723 reviews
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Strikethrough Rate:~~$77~~Discounted rate:$72USD/night
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Quality Inn Litchfield Route 66
1010 East Columbian N Blvd,
Litchfield, IL, 62056, US
4.27 stars rating. Excellent. 1179 reviews
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Strikethrough Rate:~~$93~~Discounted rate:$84USD/night
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Comfort Inn & Suites Hazelwood - St. Louis
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
4.09 stars rating. Very Good. 2017 reviews
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Strikethrough Rate:~~$92~~Discounted rate:$81USD/night
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Econo Lodge Inn & Suites Fairview Heights - St. Louis
305 Salem Place,
Fairview Heights, IL, 62208, US
3.78 stars rating. Good. 333 reviews
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Strikethrough Rate:~~$75~~Discounted rate:$68USD/night
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Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy,
Fairview Heights, IL, 62208, US
3.52 stars rating. Good. 230 reviews
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Strikethrough Rate:~~$149~~Discounted rate:$127USD/night
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Comfort Inn & Suites OFallon - St Louis Area
116 Regency Park,
O'Fallon, IL, 62269, US
2.36 stars rating. Fair. 132 reviews
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Strikethrough Rate:~~$94~~Discounted rate:$85USD/night
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Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
3.41 stars rating. Good. 1485 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$79USD/night
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Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
4.06 stars rating. Very Good. 193 reviews
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Strikethrough Rate:~~$132~~Discounted rate:$107USD/night
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Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
4.64 stars rating. Exceptional. 693 reviews
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Strikethrough Rate:~~$254~~Discounted rate:$236USD/night
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Comfort Inn & Suites Saint Louis Lafayette Square
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
3.81 stars rating. Good. 130 reviews
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Strikethrough Rate:~~$254~~Discounted rate:$229USD/night
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Radisson Hotel St. Louis Downtown Convention Center
811 N 9th St,
St. Louis, MO, 63101, US
1.44 stars rating. Fair. 124 reviews
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Strikethrough Rate:~~$299~~Discounted rate:$284USD/night
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Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
3.52 stars rating. Good. 1362 reviews
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Strikethrough Rate:~~$134~~Discounted rate:$124USD/night
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Quality Inn Saint Louis Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
3.26 stars rating. Good. 3088 reviews
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Strikethrough Rate:~~$112~~Discounted rate:$104USD/night
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River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
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$225USD/night
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MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
3.12 stars rating. Good. 216 reviews
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Strikethrough Rate:~~$199~~Discounted rate:$185USD/night
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MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
3.93 stars rating. Good. 245 reviews
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Strikethrough Rate:~~$149~~Discounted rate:$125USD/night
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Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
No Reviews Yet
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Strikethrough Rate:~~$155~~Discounted rate:$127USD/night
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Discover the University Town of Edwardsville, Illinois

Edwardsville, home to Southern Illinois University, offers visitors vibrant college town atmosphere and beautiful Illinois landscapes in Madison County. The city features university cultural attractions, historic sites, and recreational facilities that combine academic excellence with community charm. Visitors can explore campus facilities, attend cultural events, or enjoy the area's parks and outdoor recreation opportunities. The combination of university culture and community spirit creates dynamic Illinois experiences. Choice Hotels provides convenient access to university attractions while serving as excellent bases for exploring southwestern Illinois.