Book Comfort Inn Hotels in Des Moines, IA

Comfort Inn & Suites Event Center
929 3rd Street,
Des Moines, IA, 50309, US
0.39 mi from Des Moines, IA
4.19 stars rating. Very Good. 3043 reviews4.19 stars rating. Very Good. 3043 reviews
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Strikethrough Rate:~~$159~~Discounted rate:$129USD/night
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Quality Inn & Suites Des Moines - Merle Hay Road
4995 N.W. Merle Hay Road,
Des Moines, IA, 50322, US
5.94 mi from Des Moines, IA
3.74 stars rating. Good. 1240 reviews3.74 stars rating. Good. 1240 reviews
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Strikethrough Rate:~~$80~~Discounted rate:$68USD/night
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Quality Inn & Suites Des Moines Airport
5231 Fleur Drive,
Des Moines, IA, 50321, US
3.93 mi from Des Moines, IA
3.45 stars rating. Good. 1037 reviews3.45 stars rating. Good. 1037 reviews
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Strikethrough Rate:~~$90~~Discounted rate:$86USD/night
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Quality Inn
4950 NE 14th Street,
Des Moines, IA, 50313, US
4.29 mi from Des Moines, IA
3.36 stars rating. Good. 837 reviews3.36 stars rating. Good. 837 reviews
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Strikethrough Rate:~~$101~~Discounted rate:$96USD/night
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Econo Lodge Inn & Suites Fairgrounds
410 E. 30th Street,
Des Moines, IA, 50317, US
3.04 mi from Des Moines, IA
3.4 stars rating. Good. 994 reviews3.4 stars rating. Good. 994 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$104USD/night
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Country Inn & Suites by Radisson, Des Moines West, IA
1350 NW 118th Street,
Clive, IA, 50325, US
8.53 mi from Des Moines, IA
4.41 stars rating. Excellent. 438 reviews4.41 stars rating. Excellent. 438 reviews
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Strikethrough Rate:~~$129~~Discounted rate:$125USD/night
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Sleep Inn & Suites Pleasant Hill - Des Moines
5850 Morning Star Court,
Pleasant Hill, IA, 50327, US
6.35 mi from Des Moines, IA
3.88 stars rating. Good. 1462 reviews3.88 stars rating. Good. 1462 reviews
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Strikethrough Rate:~~$180~~Discounted rate:$171USD/night
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Clarion Inn Des Moines Airport
1810 Army Post Road,
Des Moines, IA, 50315, US
4.59 mi from Des Moines, IA
2.87 stars rating. Fair. 83 reviews2.87 stars rating. Fair. 83 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$94USD/night
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Sleep Inn & Suites West Des Moines near Jordan Creek
885 S. 51st Street,
West Des Moines, IA, 50265, US
8.47 mi from Des Moines, IA
4.41 stars rating. Excellent. 1248 reviews4.41 stars rating. Excellent. 1248 reviews
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Strikethrough Rate:~~$156~~Discounted rate:$140USD/night
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Comfort Inn & Suites West Des Moines
1625 Jordan Creek Parkway,
West Des Moines, IA, 50266, US
9.96 mi from Des Moines, IA
4.12 stars rating. Very Good. 604 reviews4.12 stars rating. Very Good. 604 reviews
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Strikethrough Rate:~~$129~~Discounted rate:$110USD/night
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Quality Inn & Suites Ankeny-Des Moines
201 SE Delaware Ave,
Ankeny, IA, 50021, US
9.85 mi from Des Moines, IA
3.62 stars rating. Good. 934 reviews3.62 stars rating. Good. 934 reviews
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Strikethrough Rate:~~$107~~Discounted rate:$97USD/night
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Econo Lodge Ankeny - Des Moines
2602 SE Creekview Drive,
Ankeny, IA, 50021, US
8.23 mi from Des Moines, IA
4.36 stars rating. Excellent. 1016 reviews4.36 stars rating. Excellent. 1016 reviews
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Strikethrough Rate:~~$105~~Discounted rate:$95USD/night
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Quality Inn & Suites Altoona - Des Moines
2701 Adventureland Drive,
Altoona, IA, 50009, US
7.87 mi from Des Moines, IA
3.7 stars rating. Good. 771 reviews3.7 stars rating. Good. 771 reviews
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Strikethrough Rate:~~$145~~Discounted rate:$138USD/night
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Country Inn & Suites by Radisson, Ankeny, IA
2510 SE Tones Dr,
Ankeny, IA, 50021, US
8.24 mi from Des Moines, IA
3.45 stars rating. Good. 135 reviews3.45 stars rating. Good. 135 reviews
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Strikethrough Rate:~~$155~~Discounted rate:$147USD/night
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Sleep Inn Waukee-West Des Moines
2885 Grand Prairie Parkway, Building A,
Waukee, IA, 50263, US
12.26 mi from Des Moines, IA
4.39 stars rating. Excellent. 455 reviews4.39 stars rating. Excellent. 455 reviews
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Strikethrough Rate:~~$134~~Discounted rate:$121USD/night
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Comfort Inn Altoona-Des Moines
2023 Adventureland Drive,
Altoona, IA, 50009, US
8.23 mi from Des Moines, IA
4.1 stars rating. Very Good. 735 reviews4.1 stars rating. Very Good. 735 reviews
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Strikethrough Rate:~~$194~~Discounted rate:$184USD/night
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MainStay Suites Waukee-West Des Moines
2885 Grand Prairie Prkwy., Building B,
Waukee, IA, 50263, US
12.26 mi from Des Moines, IA
4.2 stars rating. Excellent. 121 reviews4.2 stars rating. Excellent. 121 reviews
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Strikethrough Rate:~~$154~~Discounted rate:$146USD/night
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Quality Inn Indianola
1701 N Jefferson Way,
Indianola, IA, 50125, US
14.95 mi from Des Moines, IA
3.66 stars rating. Good. 722 reviews3.66 stars rating. Good. 722 reviews
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Strikethrough Rate:~~$150~~Discounted rate:$143USD/night
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Quality Inn
1258 8th St,
West Des Moines, IA, 50265, US
5.07 mi from Des Moines, IA
No Reviews YetNo Reviews Yet
Coming soonStart booking Oct 16, 2025
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Sleep Inn & Suites Ankeny - Des Moines
2406 SE Tones Drive,
Ankeny, IA, 50021, US
8.32 mi from Des Moines, IA
4.34 stars rating. Excellent. 796 reviews4.34 stars rating. Excellent. 796 reviews
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Comfort Inn & Suites Ankeny - Des Moines
215 NE Delaware Ave,
Ankeny, IA, 50021, US
10.07 mi from Des Moines, IA
4.32 stars rating. Excellent. 516 reviews4.32 stars rating. Excellent. 516 reviews
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Country Inn & Suites by Radisson, Indianola, IA
501 East Trail Ridge Avenue,
Indianola, IA, 50125, US
14.55 mi from Des Moines, IA
4.01 stars rating. Very Good. 183 reviews4.01 stars rating. Very Good. 183 reviews
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Good to know

Number of hotels

22 hotels in Des Moines

Highest Price

$184

Lowest Price

$68

Avg. rating

18 hotels near Des Moines, IA

Comfort Inn & Suites Event Center

Quality Inn & Suites Des Moines - Merle Hay Road

Quality Inn & Suites Des Moines Airport

Quality Inn

Econo Lodge Inn & Suites Fairgrounds

Country Inn & Suites by Radisson, Des Moines West, IA

Sleep Inn & Suites Pleasant Hill - Des Moines

Clarion Inn Des Moines Airport

Sleep Inn & Suites West Des Moines near Jordan Creek

Comfort Inn & Suites West Des Moines

Quality Inn & Suites Ankeny-Des Moines

Econo Lodge Ankeny - Des Moines

Quality Inn & Suites Altoona - Des Moines

Country Inn & Suites by Radisson, Ankeny, IA

Sleep Inn Waukee-West Des Moines

Comfort Inn Altoona-Des Moines

MainStay Suites Waukee-West Des Moines

Quality Inn Indianola

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Quality Inn

Sleep Inn & Suites Ankeny - Des Moines

Comfort Inn & Suites Ankeny - Des Moines

Country Inn & Suites by Radisson, Indianola, IA

Other Des Moines searches

Good to know

22 hotels in Des Moines

$184

$68

3.7 (17370 reviews)