Comfort Inn & Suites Rochester South Mayo Clinic

Welcome to our newly renovated Comfort Inn & Suites^® Rochester South Mayo Clinic hotel in Rochester, MN, conveniently located off US-63 just minutes from Rochester International Airport and the Mayo Clinic, both reachable via our shuttle running Mon-Fri from 4 a.m. to 6 p.m. Whether you’re visiting for business or leisure, we provide the modern amenities you expect, including free WiFi throughout the hotel, a free hearty breakfast each morning, an indoor heated pool for relaxation and a spacious meeting room for conferences or events. We’re also pet-friendly, meaning you don’t have to leave your furry friend behind on this trip. And if you like to stay active, visit our on-site fitness center.