Comfort Inn Tupelo Central

Coming to Tupelo for business or to explore the birthplace of Elvis Presley? Book our Comfort Inn^® in Tupelo for a relaxing place to stay and a convenient location for business or leisure travelers. We are situated near Interstate 22, Highway 45 and other major roadways traversing northern Mississippi. It’s a short drive to the Natchez Trace Parkway and attractions such as Tupelo Buffalo Park and Zoo and the Elvis Presley Birthplace Museum.