Affordable accommodations in Cape Girardeau

Staying in southern Missouri is more affordable than ever with our Quality Inn® hotel in Cape Girardeau. Our unique destination is conveniently located near popular restaurants, museums and even haunted historical sites! The region is also a playground for outdoor enthusiasts who can fish, boat, cycle or hike. We include travel amenities you’d expect when you’re looking for great value from a hotel brand you can trust. Our hotel makes it easy to stay active while you’re in Missouri with our seasonal outdoor pool. Enjoy a fresh-brewed cup of coffee in our relaxing lobby and unwind with friends. You can also grab a late-night snack in one of the vending machines.

Start your day out right with free hot breakfast every morning. Free parking is available, and you can stay connected with our free high-speed WiFi throughout the hotel.

Our spacious guest rooms include premium bedding, a flat-screen TV and USB charging stations so your mobile devices and tablets stay powered during your visit.

When you want to enjoy some of the area’s most popular attractions, our location provides easy access to the Cape Splash Family Aquatic Center, Historic Fort D, Lake Charles, Cape Jaycee Municipal Golf Course and Cape Rock Park. If you are looking to get the essentials from a hotel that focuses on giving you value for your stay in Cape Girardeau, Quality Inn has you covered.

Hotel at a glance
  • 15 minutes from Southeast Missouri State University
  • 15 minutes from Cape Girardeau Regional Airport
  • Refrigerator and microwave in guest rooms
  • Seasonal outdoor pool
  • Truck and bus parking
  • 100% smoke-free 
Book Direct Benefits
  • Lowest price, guaranteed

  • Earn Choice Privileges points on your eligible stay

Available Guest Rooms
Sun, October 1 - Mon, October 2
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Hotel Amenities

  • Premium Free WiFi
  • 100% Smoke Free Hotel
  • Free Hot Breakfast
  • Vending Machines*
  • Seasonal Outdoor Pool
  • Truck Parking
  • Outdoor Parking
  • Copy Machine
  • Fax Machine
  • No Pets Allowed
  • Government Travelers: FEMA Approved
  • Bus Parking

* Indicates services/amenities that may require an additional cost.