34 Extended Stay hotels near Clayton, MO, USA

34 Extended Stay hotels near Clayton, MO, USA

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    • 38

      MainStay Suites St. Louis - Galleria

      1.92 km from destination

      3.23 stars rating. Good. 165 reviews
      Save 16%
      Strikethrough Rate:$139Discounted rate:$116USD/night
      Member Rate
    • 27

      MainStay Suites St. Louis Airport

      11.47 km from destination

      3.93 stars rating. Good. 234 reviews
      Save 16%
      Strikethrough Rate:$115Discounted rate:$96USD/night
      Member Rate
    Below are additional hotels in the area that do not match your exact search criteria.
    • 40

      Comfort Inn St. Louis - Westport Event Center

      10.72 km from destination

      3.57 stars rating. Good. 3077 reviews
      Save 12%
      Strikethrough Rate:$99Discounted rate:$87USD/night
      Member Rate
    • 30

      Quality Inn Airport

      9.69 km from destination

      3.27 stars rating. Good. 3022 reviews
      Save 7%
      Strikethrough Rate:$80Discounted rate:$74USD/night
      Member Rate
    • 12

      Quality Inn Florissant-St. Louis

      14.02 km from destination

      3.41 stars rating. Good. 1447 reviews
      Save 7%
      Strikethrough Rate:$71Discounted rate:$66USD/night
      Member Rate
    • 32

      Comfort Inn & Suites St. Louis-Hazelwood

      14.48 km from destination

      4.12 stars rating. Very Good. 1975 reviews
      Save 12%
      Strikethrough Rate:$96Discounted rate:$85USD/night
      Member Rate
    • 30

      Comfort Inn St. Louis Airport

      11.43 km from destination

      4.07 stars rating. Very Good. 176 reviews
      Save 16%
      Strikethrough Rate:$107Discounted rate:$90USD/night
      Member Rate
    • 33

      Comfort Suites St. Louis - Sunset Hills

      12.37 km from destination

      4.71 stars rating. Exceptional. 1829 reviews
      Save 7%
      Strikethrough Rate:$114Discounted rate:$106USD/night
      Member Rate
    • 35

      Comfort Inn & Suites

      10.69 km from destination

      3.82 stars rating. Good. 92 reviews
      Save 7%
      Strikethrough Rate:$119Discounted rate:$111USD/night
      Member Rate
    • 26

      Quality Inn O'Fallon IL - St. Louis

      34.01 km from destination

      3.56 stars rating. Good. 922 reviews
      Save 15%
      Strikethrough Rate:$64Discounted rate:$55USD/night
      Member Rate
    • 21

      Quality Inn & Suites near St. Louis and I-255

      18.3 km from destination

      3.54 stars rating. Good. 1344 reviews
      Save 7%
      Strikethrough Rate:$86Discounted rate:$80USD/night
      Member Rate
    • 25

      Hollywood Casino St Louis

      17.1 km from destination

      No Reviews Yet
      Save 13%
      Strikethrough Rate:$145Discounted rate:$126USD/night
      Member Rate
      Fees included
    • 35

      Comfort Suites St Charles-St Louis

      18.85 km from destination

      4.03 stars rating. Very Good. 2063 reviews
      Save 7%
      Strikethrough Rate:$118Discounted rate:$109USD/night
      Member Rate
    • 25

      Country Inn & Suites by Radisson, St. Charles Historic District

      18.75 km from destination

      4.65 stars rating. Exceptional. 565 reviews
      Save 7%
      Strikethrough Rate:$164Discounted rate:$153USD/night
      Member Rate
    • 31

      Quality Inn & Suites Caseyville - St. Louis

      25.59 km from destination

      2.73 stars rating. Fair. 705 reviews
      Save 7%
      Strikethrough Rate:$76Discounted rate:$71USD/night
      Member Rate
    • 29

      Sleep Inn

      25.22 km from destination

      3.08 stars rating. 1020 reviews
      Save 7%
      Strikethrough Rate:$86Discounted rate:$80USD/night
      Member Rate
    • 31

      Econo Lodge Inn & Suites

      22.47 km from destination

      3.43 stars rating. Good. 373 reviews
      Save 7%
      Strikethrough Rate:$68Discounted rate:$63USD/night
      Member Rate
    • 26

      Sleep Inn O'Fallon near I-64

      35.19 km from destination

      3.39 stars rating. Good. 1322 reviews
      Save 12%
      Strikethrough Rate:$64Discounted rate:$57USD/night
      Member Rate
    • 38

      Comfort Inn & Suites Chesterfield - St. Louis

      27.48 km from destination

      3.92 stars rating. Good. 2441 reviews
      Save 18%
      Strikethrough Rate:$113Discounted rate:$92USD/night
      Member Rate
      Fees included
    • 42

      Country Inn & Suites by Radisson, St. Peters, MO

      25.19 km from destination

      4.12 stars rating. Very Good. 207 reviews
      Save 7%
      Strikethrough Rate:$109Discounted rate:$101USD/night
      Member Rate
    • 41

      Comfort Inn Alton near I-255

      33.28 km from destination

      3.66 stars rating. Good. 854 reviews
      Save 10%
      Strikethrough Rate:$89Discounted rate:$80USD/night
      Member Rate
    • 36

      Comfort Inn Collinsville near St. Louis

      28.34 km from destination

      4.19 stars rating. Very Good. 1915 reviews
      Save 19%
      Strikethrough Rate:$117Discounted rate:$95USD/night
      Member Rate
    • 31

      Comfort Inn & Suites St. Louis-O'Fallon

      34.05 km from destination

      3.68 stars rating. Good. 1862 reviews
      Save 10%
      Strikethrough Rate:$84Discounted rate:$76USD/night
      Member Rate
    • 30

      Comfort Suites Fairview Heights - St Louis

      30.27 km from destination

      3.46 stars rating. Good. 1775 reviews
      Save 7%
      Strikethrough Rate:$89Discounted rate:$83USD/night
      Member Rate
    • 28

      Sleep Inn & Suites O'Fallon MO - Technology Drive

      32.92 km from destination

      4.23 stars rating. Excellent. 1217 reviews
      Save 14%
      Strikethrough Rate:$97Discounted rate:$83USD/night
      Member Rate
    • 10

      Country Inn & Suites by Radisson, Fairview Heights, IL

      30.29 km from destination

      3.19 stars rating. Good. 218 reviews
      Save 10%
      Strikethrough Rate:$94Discounted rate:$85USD/night
      Member Rate
    • 28

      Econo Lodge Inn & Suites Fairview Heights - St. Louis

      31.16 km from destination

      3.74 stars rating. Good. 316 reviews
      Save 7%
      Strikethrough Rate:$71Discounted rate:$66USD/night
      Member Rate
    • 31

      Comfort Inn & Suites OFallon - St Louis Area

      35.18 km from destination

      2.33 stars rating. Fair. 99 reviews
      Save 10%
      Strikethrough Rate:$82Discounted rate:$74USD/night
      Member Rate
    • 34

      Comfort Inn Edwardsville - St. Louis

      31.54 km from destination

      4.17 stars rating. Very Good. 1364 reviews
      Save 10%
      Strikethrough Rate:$124Discounted rate:$112USD/night
      Member Rate
    • 11

      River City Casino & Hotel

      14.64 km from destination

      No Reviews Yet
      $195USD/night
      Fees included
    • 31

      Quality Inn Near Six Flags St. Louis

      40.91 km from destination

      4 stars rating. Very Good. 653 reviews
      Save 10%
      Strikethrough Rate:$106Discounted rate:$95USD/night
      Member Rate
    • 25

      Radisson Hotel Fairview Heights - St. Louis

      31.21 km from destination

      3.12 stars rating. Good. 131 reviews
      Save 10%
      Strikethrough Rate:$104Discounted rate:$94USD/night
      Special Rate
    • 35

      Comfort Inn Near Six Flags St. Louis

      40.77 km from destination

      4.05 stars rating. Very Good. 1721 reviews
      Save 7%
      Strikethrough Rate:$120Discounted rate:$112USD/night
      Member Rate
    • 32

      The Great Rivers, an Ascend Collection Hotel

      33.4 km from destination

      2.81 stars rating. Fair. 91 reviews
      Save 5%
      Strikethrough Rate:$113Discounted rate:$108USD/night
      Member Rate
    Change your dates to book properties below.
    • 2

      Radisson Hotel St. Louis Downtown Convention Center

      12.71 km from destination

      No Reviews Yet
      Coming soonStart booking Nov 12, 2025

    Other Clayton searches

    Good to know

    Extended stay hotels

    2 of 35 hotels in Clayton

    Highest Price

    $195

    Lowest Price

    $55

    Avg. rating

    3.3 (35195 reviews)

    Weekly Rate

    $385

    Monthly Rate

    $1,650