34 hotels near Clayton, MO, US

34 hotels near Clayton, MO, US

Show points
    • List
    • 33

      AWARD WINNER

      Comfort Suites St. Louis - Sunset Hills

      8.06 mi from destination

      4.73 stars rating. Exceptional. 2063 reviews
      Save 7%
      Strikethrough Rate:$119Discounted rate:$111USD/night
      Member Rate
    • 38

      MainStay Suites St. Louis - Galleria

      1.54 mi from destination

      3.14 stars rating. Good. 212 reviews
      Save 7%
      Strikethrough Rate:$109Discounted rate:$101USD/night
      Member Rate
    • 30

      Comfort Inn St. Louis Airport

      7.1 mi from destination

      4.06 stars rating. Very Good. 192 reviews
      Save 19%
      Strikethrough Rate:$132Discounted rate:$107USD/night
      Member Rate
    • 37

      NEW TO CHOICE

      Comfort Inn & Suites Saint Louis Lafayette Square

      6.38 mi from destination

      3.79 stars rating. Good. 127 reviews
      Save 7%
      Strikethrough Rate:$144Discounted rate:$134USD/night
      Member Rate
    • 32

      Comfort Inn & Suites Hazelwood - St. Louis

      8.84 mi from destination

      4.1 stars rating. Very Good. 2008 reviews
      Save 7%
      Strikethrough Rate:$107Discounted rate:$100USD/night
      Member Rate
    • 12

      Quality Inn Florissant-St. Louis

      8.5 mi from destination

      3.41 stars rating. Good. 1482 reviews
      Save 7%
      Strikethrough Rate:$79Discounted rate:$73USD/night
      Member Rate
    • 30

      Quality Inn Saint Louis Airport

      5.9 mi from destination

      3.26 stars rating. Good. 3081 reviews
      Save 7%
      Strikethrough Rate:$84Discounted rate:$78USD/night
      Member Rate
    • 15

      River City Casino & Hotel

      9.14 mi from destination

      No Reviews Yet
      Save 13%
      Strikethrough Rate:$145Discounted rate:$126USD/night
      Member Rate
      Fees included
    • 21

      Quality Inn & Suites near St. Louis and I-255

      11.2 mi from destination

      3.52 stars rating. Good. 1360 reviews
      Save 7%
      Strikethrough Rate:$82Discounted rate:$76USD/night
      Member Rate
    • 35

      Comfort Suites St Charles-St Louis

      11.84 mi from destination

      4.02 stars rating. Very Good. 2113 reviews
      Save 5%
      Strikethrough Rate:$139Discounted rate:$132USD/night
      Member Rate
    • 53

      NEW TO CHOICE

      Radisson Hotel St. Louis Downtown Convention Center

      7.56 mi from destination

      1.43 stars rating. Fair. 122 reviews
      Save 5%
      Strikethrough Rate:$130Discounted rate:$124USD/night
      Member Rate
    • 27

      MainStay Suites St. Louis Airport

      7.12 mi from destination

      3.92 stars rating. Good. 244 reviews
      Save 19%
      Strikethrough Rate:$143Discounted rate:$116USD/night
      Member Rate
    • 25

      Hollywood Casino St Louis

      10.77 mi from destination

      No Reviews Yet
      Save 13%
      Strikethrough Rate:$125Discounted rate:$109USD/night
      Member Rate
      Fees included
    • 25

      AWARD WINNER

      Country Inn & Suites by Radisson, St. Charles Historic District

      11.76 mi from destination

      4.64 stars rating. Exceptional. 688 reviews
      Save 7%
      Strikethrough Rate:$250Discounted rate:$232USD/night
      Member Rate
    • 42

      Country Inn & Suites by Radisson, St. Peters, MO

      15.82 mi from destination

      4.05 stars rating. Very Good. 237 reviews
      Save 7%
      Strikethrough Rate:$115Discounted rate:$107USD/night
      Member Rate
    • 36

      Comfort Inn Collinsville near St. Louis

      17.21 mi from destination

      4.2 stars rating. Excellent. 1983 reviews
      Save 10%
      Strikethrough Rate:$143Discounted rate:$129USD/night
      Member Rate
    • 38

      Comfort Inn & Suites Chesterfield - St. Louis

      17.43 mi from destination

      3.89 stars rating. Good. 2522 reviews
      Save 10%
      Strikethrough Rate:$117Discounted rate:$106USD/night
      Member Rate
      Fees included
    • 34

      Comfort Inn Edwardsville - St. Louis

      19.17 mi from destination

      4.16 stars rating. Very Good. 1387 reviews
      Save 10%
      Strikethrough Rate:$125Discounted rate:$113USD/night
      Member Rate
    • 29

      Sleep Inn & Suites O'Fallon MO - Technology Drive

      20.78 mi from destination

      4.23 stars rating. Excellent. 1283 reviews
      Save 19%
      Strikethrough Rate:$107Discounted rate:$87USD/night
      Member Rate
    • 31

      Econo Lodge Inn & Suites Granite City - St. Louis

      13.53 mi from destination

      3.46 stars rating. Good. 396 reviews
      Save 7%
      Strikethrough Rate:$69Discounted rate:$64USD/night
      Member Rate
    • 29

      Sleep Inn Saint Charles North

      15.75 mi from destination

      3.08 stars rating. Fair. 1051 reviews
      Save 7%
      Strikethrough Rate:$98Discounted rate:$91USD/night
      Member Rate
    • 30

      Comfort Suites Fairview Heights - St Louis

      18.48 mi from destination

      3.45 stars rating. Good. 1822 reviews
      Save 10%
      Strikethrough Rate:$94Discounted rate:$85USD/night
      Member Rate
    • 41

      Comfort Inn Alton near I-255

      20.3 mi from destination

      3.64 stars rating. Good. 868 reviews
      Save 10%
      Strikethrough Rate:$99Discounted rate:$89USD/night
      Member Rate
    • 31

      Quality Inn & Suites Caseyville - St. Louis

      15.57 mi from destination

      2.7 stars rating. Fair. 723 reviews
      Save 7%
      Strikethrough Rate:$77Discounted rate:$72USD/night
      Member Rate
    • 31

      Country Inn & Suites by Radisson, Fairview Heights, IL

      18.49 mi from destination

      3.16 stars rating. Good. 243 reviews
      Save 10%
      Strikethrough Rate:$99Discounted rate:$89USD/night
      Member Rate
    • 31

      Comfort Inn & Suites St. Louis-O'Fallon

      21.38 mi from destination

      3.67 stars rating. Good. 1934 reviews
      Save 7%
      Strikethrough Rate:$86Discounted rate:$80USD/night
      Member Rate
    • 26

      Quality Inn O'Fallon IL - St. Louis

      20.8 mi from destination

      3.54 stars rating. Good. 959 reviews
      Save 5%
      Strikethrough Rate:$80Discounted rate:$76USD/night
      Member Rate
    • 28

      Econo Lodge Inn & Suites Fairview Heights - St. Louis

      19.03 mi from destination

      3.78 stars rating. Good. 329 reviews
      Save 12%
      Strikethrough Rate:$75Discounted rate:$66USD/night
      Member Rate
    • 35

      Comfort Inn Near Six Flags St. Louis

      25.76 mi from destination

      4.06 stars rating. Very Good. 1786 reviews
      Save 10%
      Strikethrough Rate:$122Discounted rate:$110USD/night
      Member Rate
    • 31

      Quality Inn Pacific near Six Flags St. Louis

      25.85 mi from destination

      4.01 stars rating. Very Good. 669 reviews
      Save 10%
      Strikethrough Rate:$106Discounted rate:$95USD/night
      Member Rate
    • 26

      Sleep Inn O'Fallon near I-64

      21.54 mi from destination

      3.36 stars rating. Good. 1359 reviews
      Save 7%
      Strikethrough Rate:$80Discounted rate:$74USD/night
      Member Rate
    • 25

      NEW TO CHOICE

      Radisson Hotel Fairview Heights - St. Louis

      19.06 mi from destination

      3.52 stars rating. Good. 227 reviews
      Save 5%
      Strikethrough Rate:$114Discounted rate:$108USD/night
      Member Rate
    • 32

      NEW TO CHOICE

      The Great Rivers, an Ascend Collection Hotel

      20.37 mi from destination

      2.91 stars rating. Fair. 114 reviews
      Save 5%
      Strikethrough Rate:$139Discounted rate:$132USD/night
      Member Rate
    • 31

      Comfort Inn & Suites OFallon - St Louis Area

      21.53 mi from destination

      2.35 stars rating. Fair. 129 reviews
      Save 10%
      Strikethrough Rate:$86Discounted rate:$77USD/night
      Member Rate

    Discover the Suburban Elegance of Clayton, Missouri

    Clayton, an affluent suburb of St. Louis, offers visitors sophisticated urban amenities combined with beautiful residential neighborhoods and excellent cultural attractions. The community features upscale shopping, fine dining, and well-maintained parks that provide peaceful retreats from city life. Visitors can explore the Shaw Park area, enjoy cultural events, or easily access nearby St. Louis attractions including museums, sports venues, and entertainment districts. The area's blend of suburban charm and urban convenience creates perfect destinations for both relaxation and exploration. For accommodations, Choice Hotels provides convenient access to Clayton's attractions and greater St. Louis area amenities.

    Other Clayton searches

    Clayton hotels by brand

    Good to know

    Number of hotels

    34 hotels in Clayton

    Highest Price

    $232

    Lowest Price

    $64

    Avg. rating

    3.6 (33713 reviews)