Book Boutique Hotels in East Prairie, MO | Choice Hotels

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Comfort Inn & Suites Sikeston I-55
109 Matthews Lane,
Sikeston, MO, 63801, US
11.33 mi from East Prairie, MO 63845, USA
4.02 stars rating. Very Good. 1342 reviews4.02 stars rating. Very Good. 1342 reviews
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Quality Inn Cairo I-57
13201 Kessler Rd, Route 3 and I-57,
Cairo, IL, 62914, US
20.84 mi from East Prairie, MO 63845, USA
3.66 stars rating. Good. 560 reviews3.66 stars rating. Good. 560 reviews
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Quality Inn Charleston - Sikeston
102 Drake St., I-57 ex. 10,
Charleston, MO, 63834, US
9.07 mi from East Prairie, MO 63845, USA
3.36 stars rating. Good. 622 reviews3.36 stars rating. Good. 622 reviews
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Sleep Inn at Discovery Park of America
1111 BLue Heron Lane, Building A,
Union City, TN, 38261, US
29.51 mi from East Prairie, MO 63845, USA
4.33 stars rating. Excellent. 447 reviews4.33 stars rating. Excellent. 447 reviews
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EXTENDED STAY
MainStay Suites Union City, TN
1111 Blue Heron Lane, Building B,
Union City, TN, 38261, US
29.53 mi from East Prairie, MO 63845, USA
4.44 stars rating. Excellent. 100 reviews4.44 stars rating. Excellent. 100 reviews
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Boutique hotels

5 hotels in East Prairie

Avg. rating

4.0 (3071 reviews)