Book Top Rated Hotels in East Prairie, MO | Choice Hotels

Comfort Inn & Suites Sikeston I-55
109 Matthews Lane,
Sikeston, MO, 63801, US
11.33 mi from East Prairie, MO, US
4.02 stars rating. Very Good. 1350 reviews
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Strikethrough Rate:~~$110~~Discounted rate:$89USD/night
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Sleep Inn at Discovery Park of America
1111 BLue Heron Lane, Building A,
Union City, TN, 38261, US
29.51 mi from East Prairie, MO, US
4.35 stars rating. Excellent. 472 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$77USD/night
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Quality Inn Cairo I-57
13201 Kessler Rd, Route 3 and I-57,
Cairo, IL, 62914, US
20.84 mi from East Prairie, MO, US
3.67 stars rating. Good. 583 reviews
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Strikethrough Rate:~~$78~~Discounted rate:$74USD/night
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MainStay Suites Union City, TN
1111 Blue Heron Lane, Building B,
Union City, TN, 38261, US
29.53 mi from East Prairie, MO, US
4.43 stars rating. Excellent. 104 reviews
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Strikethrough Rate:~~$136~~Discounted rate:$126USD/night
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Top-Rated hotels

4 hotels in East Prairie

Highest Price

$126

Lowest Price

$74

Avg. rating

4.1 (2509 reviews)