12 Hotels in Florence, SC

Clarion Inn & Suites
1819 West Lucas Street, Building A,
Florence, SC, 29501, US
2.75 mi from Florence, SC
1.91 stars rating. Fair. 193 reviews1.91 stars rating. Fair. 193 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$63~~Discounted rate:$60USD/night
Member Rate
See Availability
MainStay Suites
1819 West Lucas Street, Building B,
Florence, SC, 29501, US
2.79 mi from Florence, SC
1.91 stars rating. Fair. 56 reviews1.91 stars rating. Fair. 56 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$72~~Discounted rate:$67USD/night
Member Rate
See Availability
Suburban Studios Florence - Darlington
1914 West Lucas Street, I-95 & US 52,
Florence, SC, 29501, US
2.84 mi from Florence, SC
2.92 stars rating. Fair. 1322 reviews2.92 stars rating. Fair. 1322 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$55~~Discounted rate:$51USD/night
Member Rate
See Availability
Econo Lodge
1920 West Lucas Street,
Florence, SC, 29501, US
2.86 mi from Florence, SC
2.86 stars rating. Fair. 1355 reviews2.86 stars rating. Fair. 1355 reviews
BOOK NOW AND SAVE 12%
Strikethrough Rate:~~$63~~Discounted rate:$56USD/night
Member Rate
See Availability
Park Inn by Radisson Florence, SC
1729 Mandeville Road,
Florence, SC, 29501, US
3.06 mi from Florence, SC
4.29 stars rating. Excellent. 329 reviews4.29 stars rating. Excellent. 329 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$111~~Discounted rate:$105USD/night
Member Rate
See Availability
Sleep Inn Florence North
1833 Florence Park Dr., I-95 & US 52,
Florence, SC, 29501, US
3.31 mi from Florence, SC
3.74 stars rating. Good. 1974 reviews3.74 stars rating. Good. 1974 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$80~~Discounted rate:$74USD/night
Member Rate
See Availability
Comfort Suites Florence I-95
2120 West Lucas Street,
Florence, SC, 29501, US
3.32 mi from Florence, SC
4.27 stars rating. Excellent. 2602 reviews4.27 stars rating. Excellent. 2602 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$117~~Discounted rate:$111USD/night
Member Rate
See Availability
Comfort Inn & Suites
527 Woody Jones Blvd.,
Florence, SC, 29501, US
3.9 mi from Florence, SC
4.49 stars rating. Excellent. 1167 reviews4.49 stars rating. Excellent. 1167 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$141~~Discounted rate:$134USD/night
Member Rate
See Availability
Quality Inn & Suites Florence Civic Center
150 Dunbarton Drive,
Florence, SC, 29501, US
4.24 mi from Florence, SC
3.95 stars rating. Good. 1736 reviews3.95 stars rating. Good. 1736 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$101~~Discounted rate:$94USD/night
Member Rate
See Availability
Quality Inn
903 South Fifth Street,
Hartsville, SC, 29550, US
20.62 mi from Florence, SC
2.94 stars rating. Fair. 392 reviews2.94 stars rating. Fair. 392 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$76~~Discounted rate:$70USD/night
Member Rate
See Availability
Quality Inn & Suites
202 North Ron McNair Blvd.,
Lake City, SC, 29560, US
22.06 mi from Florence, SC
3.34 stars rating. Good. 98 reviews3.34 stars rating. Good. 98 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$143~~Discounted rate:$133USD/night
Member Rate
See Availability

Change your dates to book properties below.

Rodeway Inn
415 S. Irby St.,
Florence, SC, 29501, US
0.46 mi from Florence, SC
No Reviews YetNo Reviews Yet
Coming soonStart booking Sep 30, 2025
See Availability

Good to know

Number of hotels

12 hotels in Florence

Highest Price

$134

Lowest Price

$51

Avg. rating

11 hotels near Florence, SC

Clarion Inn & Suites

MainStay Suites

Suburban Studios Florence - Darlington

Econo Lodge

Park Inn by Radisson Florence, SC

Sleep Inn Florence North

Comfort Suites Florence I-95

Comfort Inn & Suites

Quality Inn & Suites Florence Civic Center

Quality Inn

Quality Inn & Suites

Change your dates to book properties below.

Rodeway Inn

Other Florence searches

Good to know

12 hotels in Florence

$134

$51

3.1 (11224 reviews)