Book Quality Hotels in Florence, SC - Choice Hotels

3 of 12 hotels near Florence, SC match your filters

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Pet friendly

Pool

Quality Inn & Suites Florence Civic Center
150 Dunbarton Drive,
Florence, SC, 29501, US
4.24 mi from Florence, SC
3.95 stars rating. Good. 1718 reviews3.95 stars rating. Good. 1718 reviews
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Strikethrough Rate:~~$105~~Discounted rate:$100USD/night
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Quality Inn
903 South Fifth Street,
Hartsville, SC, 29550, US
20.62 mi from Florence, SC
2.95 stars rating. Fair. 387 reviews2.95 stars rating. Fair. 387 reviews
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Strikethrough Rate:~~$75~~Discounted rate:$71USD/night
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Quality Inn & Suites
202 North Ron McNair Blvd.,
Lake City, SC, 29560, US
22.06 mi from Florence, SC
3.34 stars rating. Good. 95 reviews3.34 stars rating. Good. 95 reviews
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Strikethrough Rate:~~$162~~Discounted rate:$154USD/night
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Below are additional hotels in the area that do not match your exact search criteria.

Clarion Inn & Suites
1819 West Lucas Street, Building A,
Florence, SC, 29501, US
2.75 mi from Florence, SC
1.92 stars rating. Fair. 192 reviews1.92 stars rating. Fair. 192 reviews
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Strikethrough Rate:~~$62~~Discounted rate:$59USD/night
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Suburban Studios Florence - Darlington
1914 West Lucas Street, I-95 & US 52,
Florence, SC, 29501, US
2.84 mi from Florence, SC
2.92 stars rating. Fair. 1317 reviews2.92 stars rating. Fair. 1317 reviews
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Strikethrough Rate:~~$60~~Discounted rate:$57USD/night
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MainStay Suites
1819 West Lucas Street, Building B,
Florence, SC, 29501, US
2.79 mi from Florence, SC
1.92 stars rating. Fair. 50 reviews1.92 stars rating. Fair. 50 reviews
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Strikethrough Rate:~~$65~~Discounted rate:$62USD/night
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Country Inn & Suites by Radisson, Florence, SC
1739 Mandeville Road,
Florence, SC, 29501-7026, US
3.07 mi from Florence, SC
3.2 stars rating. Good. 265 reviews3.2 stars rating. Good. 265 reviews
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Strikethrough Rate:~~$129~~Discounted rate:$116USD/night
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Econo Lodge
1920 West Lucas Street,
Florence, SC, 29501, US
2.86 mi from Florence, SC
2.87 stars rating. Fair. 1347 reviews2.87 stars rating. Fair. 1347 reviews
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Strikethrough Rate:~~$60~~Discounted rate:$54USD/night
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Sleep Inn Florence North
1833 Florence Park Dr., I-95 & US 52,
Florence, SC, 29501, US
3.31 mi from Florence, SC
3.73 stars rating. Good. 1962 reviews3.73 stars rating. Good. 1962 reviews
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Strikethrough Rate:~~$90~~Discounted rate:$86USD/night
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Comfort Suites Florence I-95
2120 West Lucas Street,
Florence, SC, 29501, US
3.32 mi from Florence, SC
4.27 stars rating. Excellent. 2579 reviews4.27 stars rating. Excellent. 2579 reviews
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Strikethrough Rate:~~$149~~Discounted rate:$142USD/night
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Comfort Inn & Suites
527 Woody Jones Blvd.,
Florence, SC, 29501, US
3.9 mi from Florence, SC
4.5 stars rating. Excellent. 1143 reviews4.5 stars rating. Excellent. 1143 reviews
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Strikethrough Rate:~~$159~~Discounted rate:$151USD/night
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Park Inn by Radisson Florence, SC
1729 Mandeville Road,
Florence, SC, 29501, US
3.06 mi from Florence, SC
4.27 stars rating. Excellent. 313 reviews4.27 stars rating. Excellent. 313 reviews
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Strikethrough Rate:~~$134~~Discounted rate:$127USD/night
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Change your dates to book properties below.

Rodeway Inn
415 S. Irby St.,
Florence, SC, 29501, US
0.46 mi from Florence, SC
No Reviews YetNo Reviews Yet
Coming soonStart booking Jul 31, 2025
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Good to know

Number of hotels

3 of 13 hotels in Florence

Highest Price

$154

Lowest Price

$54

Avg. rating

3.1 (11368 reviews)