Book Quality Hotels in Florence, SC - Choice Hotels

3 of 11 hotels near Florence, SC match your filters

Show points

Pet friendly

Pool

Quality Inn & Suites Florence Civic Center
150 Dunbarton Drive,
Florence, SC, 29501, US
4.24 mi from Florence, SC
3.95 stars rating. Good. 1715 reviews3.95 stars rating. Good. 1715 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$100~~Discounted rate:$93USD/night
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Quality Inn
903 South Fifth Street,
Hartsville, SC, 29550, US
20.62 mi from Florence, SC
2.95 stars rating. Fair. 386 reviews2.95 stars rating. Fair. 386 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$76~~Discounted rate:$70USD/night
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Quality Inn & Suites
202 North Ron McNair Blvd.,
Lake City, SC, 29560, US
22.06 mi from Florence, SC
3.34 stars rating. Good. 95 reviews3.34 stars rating. Good. 95 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$137~~Discounted rate:$128USD/night
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Below are additional hotels in the area that do not match your exact search criteria.

Suburban Studios Florence - Darlington
1914 West Lucas Street, I-95 & US 52,
Florence, SC, 29501, US
2.84 mi from Florence, SC
2.92 stars rating. Fair. 1317 reviews2.92 stars rating. Fair. 1317 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$55~~Discounted rate:$51USD/night
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Clarion Inn & Suites
1819 West Lucas Street, Building A,
Florence, SC, 29501, US
2.75 mi from Florence, SC
1.92 stars rating. Fair. 192 reviews1.92 stars rating. Fair. 192 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$62~~Discounted rate:$59USD/night
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MainStay Suites
1819 West Lucas Street, Building B,
Florence, SC, 29501, US
2.79 mi from Florence, SC
1.92 stars rating. Fair. 50 reviews1.92 stars rating. Fair. 50 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$65~~Discounted rate:$60USD/night
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Country Inn & Suites by Radisson, Florence, SC
1739 Mandeville Road,
Florence, SC, 29501-7026, US
3.07 mi from Florence, SC
3.19 stars rating. Good. 264 reviews3.19 stars rating. Good. 264 reviews
BOOK NOW AND SAVE 10%
Strikethrough Rate:~~$114~~Discounted rate:$103USD/night
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Sleep Inn Florence North
1833 Florence Park Dr., I-95 & US 52,
Florence, SC, 29501, US
3.31 mi from Florence, SC
3.73 stars rating. Good. 1961 reviews3.73 stars rating. Good. 1961 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$80~~Discounted rate:$74USD/night
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Comfort Suites Florence I-95
2120 West Lucas Street,
Florence, SC, 29501, US
3.32 mi from Florence, SC
4.27 stars rating. Excellent. 2578 reviews4.27 stars rating. Excellent. 2578 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$118~~Discounted rate:$112USD/night
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Econo Lodge
1920 West Lucas Street,
Florence, SC, 29501, US
2.86 mi from Florence, SC
2.87 stars rating. Fair. 1347 reviews2.87 stars rating. Fair. 1347 reviews
BOOK NOW AND SAVE 12%
Strikethrough Rate:~~$60~~Discounted rate:$53USD/night
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Comfort Inn & Suites
527 Woody Jones Blvd.,
Florence, SC, 29501, US
3.9 mi from Florence, SC
4.5 stars rating. Excellent. 1142 reviews4.5 stars rating. Excellent. 1142 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$129~~Discounted rate:$123USD/night
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Change your dates to book properties below.

Rodeway Inn
415 S. Irby St.,
Florence, SC, 29501, US
0.46 mi from Florence, SC
No Reviews YetNo Reviews Yet
Coming soonStart booking Jul 31, 2025
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Park Inn by Radisson Florence, SC
1729 Mandeville Road,
Florence, SC, 29501, US
3.06 mi from Florence, SC
4.29 stars rating. Excellent. 310 reviews4.29 stars rating. Excellent. 310 reviews
Sold outfor your selected dates
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Good to know

Number of hotels

3 of 13 hotels in Florence

Highest Price

$128

Lowest Price

$51

Avg. rating

3.1 (11357 reviews)