Book Quality Hotels in Florence, SC - Choice Hotels

3 of 12 hotels near Florence, SC match your filters

Show points

Pet friendly

Pool

Quality Inn & Suites Florence Civic Center
150 Dunbarton Drive,
Florence, SC, 29501, US
4.24 mi from Florence, SC
3.95 stars rating. Good. 1716 reviews3.95 stars rating. Good. 1716 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$105~~Discounted rate:$100USD/night
See Availability
Quality Inn
903 South Fifth Street,
Hartsville, SC, 29550, US
20.62 mi from Florence, SC
2.95 stars rating. Fair. 386 reviews2.95 stars rating. Fair. 386 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$75~~Discounted rate:$71USD/night
See Availability
Quality Inn & Suites
202 North Ron McNair Blvd.,
Lake City, SC, 29560, US
22.06 mi from Florence, SC
3.34 stars rating. Good. 95 reviews3.34 stars rating. Good. 95 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$162~~Discounted rate:$154USD/night
See Availability

Below are additional hotels in the area that do not match your exact search criteria.

Clarion Inn & Suites
1819 West Lucas Street, Building A,
Florence, SC, 29501, US
2.75 mi from Florence, SC
1.92 stars rating. Fair. 192 reviews1.92 stars rating. Fair. 192 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$62~~Discounted rate:$59USD/night
See Availability
Suburban Studios Florence - Darlington
1914 West Lucas Street, I-95 & US 52,
Florence, SC, 29501, US
2.84 mi from Florence, SC
2.92 stars rating. Fair. 1317 reviews2.92 stars rating. Fair. 1317 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$60~~Discounted rate:$57USD/night
See Availability
MainStay Suites
1819 West Lucas Street, Building B,
Florence, SC, 29501, US
2.79 mi from Florence, SC
1.92 stars rating. Fair. 50 reviews1.92 stars rating. Fair. 50 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$65~~Discounted rate:$62USD/night
See Availability
Sleep Inn Florence North
1833 Florence Park Dr., I-95 & US 52,
Florence, SC, 29501, US
3.31 mi from Florence, SC
3.73 stars rating. Good. 1961 reviews3.73 stars rating. Good. 1961 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$95~~Discounted rate:$90USD/night
See Availability
Econo Lodge
1920 West Lucas Street,
Florence, SC, 29501, US
2.86 mi from Florence, SC
2.87 stars rating. Fair. 1347 reviews2.87 stars rating. Fair. 1347 reviews
BOOK NOW AND SAVE 10%
Strikethrough Rate:~~$60~~Discounted rate:$54USD/night
See Availability
Country Inn & Suites by Radisson, Florence, SC
1739 Mandeville Road,
Florence, SC, 29501-7026, US
3.07 mi from Florence, SC
3.2 stars rating. Good. 265 reviews3.2 stars rating. Good. 265 reviews
BOOK NOW AND SAVE 10%
Strikethrough Rate:~~$149~~Discounted rate:$134USD/night
See Availability
Comfort Suites Florence I-95
2120 West Lucas Street,
Florence, SC, 29501, US
3.32 mi from Florence, SC
4.27 stars rating. Excellent. 2579 reviews4.27 stars rating. Excellent. 2579 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$159~~Discounted rate:$151USD/night
See Availability
Comfort Inn & Suites
527 Woody Jones Blvd.,
Florence, SC, 29501, US
3.9 mi from Florence, SC
4.5 stars rating. Excellent. 1143 reviews4.5 stars rating. Excellent. 1143 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$159~~Discounted rate:$151USD/night
See Availability
Park Inn by Radisson Florence, SC
1729 Mandeville Road,
Florence, SC, 29501, US
3.06 mi from Florence, SC
4.27 stars rating. Excellent. 312 reviews4.27 stars rating. Excellent. 312 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$154~~Discounted rate:$146USD/night
See Availability

Change your dates to book properties below.

Rodeway Inn
415 S. Irby St.,
Florence, SC, 29501, US
0.46 mi from Florence, SC
No Reviews YetNo Reviews Yet
Coming soonStart booking Jul 31, 2025
See Availability

Other Florence searches

All Hotels in Florence

Boutique Hotels in Florence

Hotel Deals in Florence

Extended Stay Hotels in Florence

Pet Friendly Hotels in Florence

Top Rated Hotels in Florence

Good to know

Number of hotels

12 of 13 hotels in Florence

Highest Price

$154

Lowest Price

$54

Avg. rating

3.1 (11363 reviews)