Book Comfort Suites Hotels in Isle of Palms, SC

Cambria Hotel Mount Pleasant - Charleston
1472 N HIGHWAY 17,
Mount Pleasant, SC, 29464, US
5.29 mi from Isle of Palms, SC
4.54 stars rating. Excellent. 2193 reviews4.54 stars rating. Excellent. 2193 reviews
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Strikethrough Rate:~~$126~~Discounted rate:$118USD/night
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Comfort Suites at Isle of Palms Connector
1130 Hungryneck Blvd.,
Mount Pleasant, SC, 29464, US
4.43 mi from Isle of Palms, SC
4.03 stars rating. Very Good. 2035 reviews4.03 stars rating. Very Good. 2035 reviews
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Strikethrough Rate:~~$116~~Discounted rate:$105USD/night
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Comfort Inn & Suites Patriots Point
196 Patriots Point Rd,
Mount Pleasant, SC, 29464, US
8.14 mi from Isle of Palms, SC
4.18 stars rating. Very Good. 994 reviews4.18 stars rating. Very Good. 994 reviews
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Strikethrough Rate:~~$115~~Discounted rate:$98USD/night
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Quality Inn Mt. Pleasant - Charleston
310 Johnnie Dodds Blvd.,
Mount Pleasant, SC, 29464, US
7.96 mi from Isle of Palms, SC
3.48 stars rating. Good. 526 reviews3.48 stars rating. Good. 526 reviews
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Strikethrough Rate:~~$92~~Discounted rate:$83USD/night
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Sleep Inn Mt. Pleasant - Charleston
299 Wingo Way,
Mount Pleasant, SC, 29464, US
8 mi from Isle of Palms, SC
3.89 stars rating. Good. 1800 reviews3.89 stars rating. Good. 1800 reviews
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Strikethrough Rate:~~$101~~Discounted rate:$91USD/night
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Comfort Inn Downtown Charleston
144 Bee St.,
Charleston, SC, 29401, US
11.44 mi from Isle of Palms, SC
3.7 stars rating. Good. 3707 reviews3.7 stars rating. Good. 3707 reviews
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Strikethrough Rate:~~$112~~Discounted rate:$96USD/night
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Sleep Inn Charleston - West Ashley
1524 Savannah Hwy, US 17 S,
Charleston, SC, 29407, US
14.63 mi from Isle of Palms, SC
3.97 stars rating. Good. 2657 reviews3.97 stars rating. Good. 2657 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$90USD/night
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Inn at I'On, an Ascend Collection Hotel
148 Civitas Street,
Mount Pleasant, SC, 29464, US
7.1 mi from Isle of Palms, SC
4.66 stars rating. Exceptional. 347 reviews4.66 stars rating. Exceptional. 347 reviews
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Strikethrough Rate:~~$249~~Discounted rate:$237USD/night
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Church Street Inn, an Ascend Collection Hotel
177 Church Street,
Charleston, SC, 29401, US
10.02 mi from Isle of Palms, SC
4.44 stars rating. Excellent. 635 reviews4.44 stars rating. Excellent. 635 reviews
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Strikethrough Rate:~~$191~~Discounted rate:$182USD/night
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Comfort Inn & Suites Charleston Airport Convention Center
4715 Saul White Blvd,
North Charleston, SC, 29418, US
15.5 mi from Isle of Palms, SC
4.17 stars rating. Very Good. 1130 reviews4.17 stars rating. Very Good. 1130 reviews
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Strikethrough Rate:~~$104~~Discounted rate:$94USD/night
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Comfort Suites Charleston West Ashley
2080 Savannah Highway,
Charleston, SC, 29407, US
15.97 mi from Isle of Palms, SC
4.31 stars rating. Excellent. 2705 reviews4.31 stars rating. Excellent. 2705 reviews
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Strikethrough Rate:~~$124~~Discounted rate:$112USD/night
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Quality Inn Charleston - West Ashley
2237 Savannah Hwy.,
Charleston, SC, 29414, US
16.37 mi from Isle of Palms, SC
3.13 stars rating. Good. 463 reviews3.13 stars rating. Good. 463 reviews
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Strikethrough Rate:~~$83~~Discounted rate:$77USD/night
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Quality Inn Coliseum
5055 North Arco Lane,
North Charleston, SC, 29418, US
15.72 mi from Isle of Palms, SC
3.19 stars rating. Good. 516 reviews3.19 stars rating. Good. 516 reviews
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Strikethrough Rate:~~$97~~Discounted rate:$90USD/night
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Country Inn & Suites By Radisson, Charleston North, SC
7429 Stafford Rd,
North Charleston, SC, 29406, US
19.11 mi from Isle of Palms, SC
3.29 stars rating. Good. 132 reviews3.29 stars rating. Good. 132 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$92USD/night
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Quality Inn & Suites North Charleston - Ashley Phosphate
2499 La Quinta Lane,
North Charleston, SC, 29420, US
19.31 mi from Isle of Palms, SC
2.72 stars rating. Fair. 752 reviews2.72 stars rating. Fair. 752 reviews
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Strikethrough Rate:~~$82~~Discounted rate:$74USD/night
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Sleep Inn North Charleston Ashley Phosphate
7435 Northside Dr.,
North Charleston, SC, 29420, US
19.44 mi from Isle of Palms, SC
3.45 stars rating. Good. 853 reviews3.45 stars rating. Good. 853 reviews
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Strikethrough Rate:~~$89~~Discounted rate:$83USD/night
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Clarion Pointe Charleston - West Ashley
2455 Savannah Highway,
Charleston, SC, 29414, US
16.98 mi from Isle of Palms, SC
2.23 stars rating. Fair. 235 reviews2.23 stars rating. Fair. 235 reviews
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Strikethrough Rate:~~$91~~Discounted rate:$85USD/night
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Quality Inn Goose Creek - Charleston
103 Red Bank Road,
Goose Creek, SC, 29445, US
21.12 mi from Isle of Palms, SC
3.63 stars rating. Good. 883 reviews3.63 stars rating. Good. 883 reviews
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Strikethrough Rate:~~$90~~Discounted rate:$84USD/night
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Rodeway Inn North Charleston - Ashley Phosphate
2311 Ashley Phosphate,
North Charleston, SC, 29406, US
19.11 mi from Isle of Palms, SC
2.84 stars rating. Fair. 564 reviews2.84 stars rating. Fair. 564 reviews
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Strikethrough Rate:~~$79~~Discounted rate:$74USD/night
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Econo Lodge
401 Goose Creek Blvd. N.,
Goose Creek, SC, 29445-2971, US
21.71 mi from Isle of Palms, SC
3.71 stars rating. Good. 625 reviews3.71 stars rating. Good. 625 reviews
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Strikethrough Rate:~~$84~~Discounted rate:$80USD/night
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Econo Lodge North
7415 Northside Dr.,
North Charleston, SC, 29420, US
19.43 mi from Isle of Palms, SC
2.68 stars rating. Fair. 744 reviews2.68 stars rating. Fair. 744 reviews
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Strikethrough Rate:~~$70~~Discounted rate:$65USD/night
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Suburban Studios North Charleston I-526
4620 Dorchester Road,
North Charleston, SC, 29405, US
15.58 mi from Isle of Palms, SC
1.94 stars rating. Fair. 50 reviews1.94 stars rating. Fair. 50 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$101USD/night
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Econo Lodge Coliseum
4725 Saul White Blvd.,
North Charleston, SC, 29418, US
15.45 mi from Isle of Palms, SC
4.54 stars rating. Excellent. 519 reviews4.54 stars rating. Excellent. 519 reviews
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Comfort Inn & Suites North Charleston - Northwoods
2470 Prospect Dr,
Charleston, SC, 29406, US
19.25 mi from Isle of Palms, SC
No Reviews YetNo Reviews Yet
Coming soonStart booking Jan 02, 2026
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Good to know

Number of hotels

24 hotels in Isle of Palms

Highest Price

$237

Lowest Price

$65

Avg. rating

22 hotels near Isle of Palms, SC

Cambria Hotel Mount Pleasant - Charleston

Comfort Suites at Isle of Palms Connector

Comfort Inn & Suites Patriots Point

Quality Inn Mt. Pleasant - Charleston

Sleep Inn Mt. Pleasant - Charleston

Comfort Inn Downtown Charleston

Sleep Inn Charleston - West Ashley

Inn at I'On, an Ascend Collection Hotel

Church Street Inn, an Ascend Collection Hotel

Comfort Inn & Suites Charleston Airport Convention Center

Comfort Suites Charleston West Ashley

Quality Inn Charleston - West Ashley

Quality Inn Coliseum

Country Inn & Suites By Radisson, Charleston North, SC

Quality Inn & Suites North Charleston - Ashley Phosphate

Sleep Inn North Charleston Ashley Phosphate

Clarion Pointe Charleston - West Ashley

Quality Inn Goose Creek - Charleston

Rodeway Inn North Charleston - Ashley Phosphate

Econo Lodge

Econo Lodge North

Suburban Studios North Charleston I-526

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Econo Lodge Coliseum

Comfort Inn & Suites North Charleston - Northwoods

Other Isle of Palms searches

Good to know

24 hotels in Isle of Palms

$237

$65

3.4 (25065 reviews)