Book Comfort Inn Hotels in Simpsonville, SC

Comfort Suites Simpsonville - Greenville
3971 Grandview Drive,
Simpsonville, SC, 29680, US
4.08 stars rating. Very Good. 1387 reviews
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Strikethrough Rate:~~$125~~Discounted rate:$113USD/night
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Comfort Suites Greenville Airport
1371 Garlington Road,
Greenville, SC, 29615, US
4.54 stars rating. Excellent. 937 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$104USD/night
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Comfort Inn Greenville - Haywood Mall
246 Congaree Road,
Greenville, SC, 29607, US
3.83 stars rating. Good. 1174 reviews
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Strikethrough Rate:~~$93~~Discounted rate:$89USD/night
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Comfort Suites Piedmont - Greenville South
10 Kalyns Way,
Piedmont, SC, 29673, US
4.07 stars rating. Very Good. 966 reviews
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Strikethrough Rate:~~$122~~Discounted rate:$110USD/night
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AWARD WINNER
Comfort Inn & Suites Greer - Greenville
1315 West Wade Hampton Blvd.,
Greer, SC, 29650, US
4.37 stars rating. Excellent. 428 reviews
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Strikethrough Rate:~~$112~~Discounted rate:$101USD/night
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Comfort Suites Anderson-Clemson
118 Interstate Blvd.,
Anderson, SC, 29621, US
4.14 stars rating. Very Good. 1315 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$107USD/night
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Comfort Suites At WestGate Mall
458 West Blackstock Road,
Spartanburg, SC, 29301, US
4.08 stars rating. Very Good. 2168 reviews
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Strikethrough Rate:~~$113~~Discounted rate:$102USD/night
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Comfort Suites Clinton near Presbyterian College
12865 Hwy 56 North,
Clinton, SC, 29325, US
3.93 stars rating. Good. 1619 reviews
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Strikethrough Rate:~~$116~~Discounted rate:$105USD/night
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Comfort Inn & Suites Spartanburg North
154 Candlenut Lane, I-85 Exit 75,
Spartanburg, SC, 29316, US
3.64 stars rating. Good. 1469 reviews
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Strikethrough Rate:~~$91~~Discounted rate:$82USD/night
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Quality Inn Simpsonville-Greenville
3755 Grandview Drive,
Simpsonville, SC, 29680, US
3.5 stars rating. Good. 673 reviews
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Strikethrough Rate:~~$76~~Discounted rate:$71USD/night
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Quality Inn & Suites Greenville - Haywood Mall
50 Orchard Park Dr.,
Greenville, SC, 29615-3565, US
3.74 stars rating. Good. 1622 reviews
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Strikethrough Rate:~~$78~~Discounted rate:$73USD/night
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Sleep Inn at Greenville Convention Center
231 N Pleasantburg Drive,
Greenville, SC, 29607, US
3.95 stars rating. Good. 1254 reviews
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Strikethrough Rate:~~$92~~Discounted rate:$87USD/night
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MainStay Suites Greenville Airport
2671 Dry Pocket Rd,
Greer, SC, 29650, US
3.6 stars rating. Good. 723 reviews
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Strikethrough Rate:~~$81~~Discounted rate:$75USD/night
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Quality Inn & Suites Greenville near downtown
10 Mills Ave.,
Greenville, SC, 29605, US
3.32 stars rating. Good. 1013 reviews
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Strikethrough Rate:~~$84~~Discounted rate:$78USD/night
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Quality Inn Duncan Spartanburg West
1391 E. Main St.,
Duncan, SC, 29334, US
3.88 stars rating. Good. 597 reviews
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Strikethrough Rate:~~$75~~Discounted rate:$71USD/night
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Quality Inn Greer - Greenville
611 West Wade Hampton Blvd.,
Greer, SC, 29650, US
3.13 stars rating. Good. 522 reviews
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Strikethrough Rate:~~$76~~Discounted rate:$71USD/night
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Quality Inn & Suites Easley - Greenville
5539 Calhoun Memorial Hwy., US 123,
Easley, SC, 29640-3871, US
3.7 stars rating. Good. 520 reviews
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Strikethrough Rate:~~$75~~Discounted rate:$70USD/night
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Quality Inn Clemson near University
3430 Clemson Blvd,
Anderson, SC, 29621, US
3.36 stars rating. Good. 650 reviews
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Strikethrough Rate:~~$70~~Discounted rate:$65USD/night
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Rodeway Inn Anderson North - Clemson
4515 Clemson Blvd,
Anderson, SC, 29621, US
3.85 stars rating. Good. 362 reviews
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Strikethrough Rate:~~$66~~Discounted rate:$63USD/night
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Quality Inn Spartanburg Northwest
6690 Pottery Rd,
Spartanburg, SC, 29303, US
3.65 stars rating. Good. 164 reviews
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Strikethrough Rate:~~$80~~Discounted rate:$72USD/night
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Quality Inn Clinton - Laurens I-26
105 Trade Street,
Clinton, SC, 29325, US
3.55 stars rating. Good. 709 reviews
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Strikethrough Rate:~~$82~~Discounted rate:$74USD/night
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Country Inn & Suites by Radisson, Anderson, SC
116 Interstate Blvd,
Anderson, SC, 29621, US
3.57 stars rating. Good. 187 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$111USD/night
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Sleep Inn Spartanburg Southwest
501 South Blackstock Road,
Spartanburg, SC, 29301, US
2.95 stars rating. Fair. 758 reviews
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Strikethrough Rate:~~$76~~Discounted rate:$70USD/night
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Rodeway Inn Laurens
102 Bolt Dr,
Laurens, SC, 29360, US
3.59 stars rating. Good. 176 reviews
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Strikethrough Rate:~~$77~~Discounted rate:$73USD/night
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AWARD WINNER
Rodeway Inn Expo Center
2070 New Cut Rd.,
Spartanburg, SC, 29303, US
2.95 stars rating. Fair. 539 reviews
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Strikethrough Rate:~~$72~~Discounted rate:$68USD/night
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Suburban Studios Spartanburg - I-26
1993 Reidville Road,
Spartanburg, SC, 29301, US
2.42 stars rating. Fair. 86 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$79USD/night
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NEW TO CHOICE
Clarion Inn
5009 Pelham Road,
Greenville, SC, 29615, US
No Reviews Yet
Coming soonStart booking Jul 16, 2026
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