Comfort Inn & Suites Near Medical Center

3.39 stars rating. Good.
Sold Out
Sat, Apr 18, 2026 to Sun, Apr 19, 2026

Overview

Inviting accommodations near South Texas Medical Center

San Antonio is a major city along the scenic San Antonio River in the south-central part of the state. Home to the world-famous Alamo, the city is rich in colonial history. San  Antonio is also a growing arts-, cultural- and culinary hotspot. Make our smoke-free Comfort Inn & Suites® Near Medical Center hotel your headquarters for a visit to this great city. Whether you’re in town for business or leisure, we can accommodate your travel needs. We have meeting and event space as well as a business center and a work desk in every room.

Highlights

  • Indoor Pool*
  • Free WiFi
  • Free WiFi
  • Free Hot Breakfast
  • Vending Machines*
  • Check in / out3:00 PM / 11:00 AM

*May require an additional cost

Guest Rooms

Available Guest Rooms

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Amenities

Featured Amenities(20)

  • Indoor Pool*
  • Free WiFi
  • Free WiFi
  • Free Hot Breakfast
  • Vending Machines*
  • Truck Parking
  • Exercise Room
  • Government Travelers: FEMA Approved
  • Copy Machine*

*May require an additional cost

Info

Essential details

  • Check-In3:00 PM
  • Check-Out11:00 AM
  • No Smoking100% Smoke Free Hotel
  • Phone Number(726) 226-0661
  • ChildrenAnyone aged 18 and under, at time of booking, stay for free
  • Fax (210) 733-0035
  • Pets
    Pets Allowed: No
    General: Only service animals are permitted, free of charge.

Good to know

Hotel alerts
IH 10 & Vance Jackson Road Exit 565B. Should be 18 yrs. old to rent a room, w/ a valid govt. issued photo ID w/ a matching debit/credit card. On arrival date, Card will be authorized for the full amount of stay including $250 deposit. Please check w/ your card provider regarding auth policies holds. Cash is not accepted, only at check-out. Smoking in guest rooms or any other non-designated area will result in a min. of $250 cleaning fee. All reservations are non-refundable & non-cancellable. Property does not accept Tap & Pay, Chime, Cashapp, Paypal, Sofi, Onepay, Venmo, Atlas Cards as the payment method. Sorry for any Inconvience & Thank you for choosing and trusting us.