17 hotels near Santa Fe, TX

17 hotels near Santa Fe, TX

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    • 14
      Comfort Inn & Suites

      4.99 mi from destination

      2.51 stars rating. Fair. 358 reviews
      Save 16%
      Strikethrough Rate:$77Discounted rate:$64USD/night
      Member Rate
    • 29
      Quality Inn Texas City I-45

      5.01 mi from destination

      3.51 stars rating. Good. 445 reviews
      Save 7%
      Strikethrough Rate:$69Discounted rate:$64USD/night
      Member Rate
    • 33
      Comfort Suites near NASA - Clear Lake

      11.46 mi from destination

      3.9 stars rating. Good. 1134 reviews
      Save 5%
      Strikethrough Rate:$75Discounted rate:$71USD/night
      Member Rate
    • 9
      Comfort Suites Seabrook - Kemah

      15.44 mi from destination

      3.4 stars rating. Good. 222 reviews
      Save 10%
      Strikethrough Rate:$69Discounted rate:$62USD/night
      Special Rate
    • 28
      Quality Inn & Suites Seabrook- NASA- Kemah

      13.23 mi from destination

      4.38 stars rating. Excellent. 1175 reviews
      Save 10%
      Strikethrough Rate:$87Discounted rate:$78USD/night
      Member Rate
    • 35
      MainStay Suites Houston NASA/Clear Lake

      12.26 mi from destination

      3.37 stars rating. Good. 90 reviews
      Save 7%
      Strikethrough Rate:$89Discounted rate:$83USD/night
      Member Rate
    • 39
      Econo Lodge Galveston Seawall

      19.79 mi from destination

      2.76 stars rating. Fair. 101 reviews
      Save 5%
      Strikethrough Rate:$60Discounted rate:$57USD/night
      Member Rate
    • 31
      Sleep Inn & Suites Galveston Island

      16.78 mi from destination

      2.96 stars rating. Fair. 827 reviews
      Save 7%
      Strikethrough Rate:$83Discounted rate:$77USD/night
      Member Rate
    • 53
      Comfort Suites La Porte - Baytown

      19.61 mi from destination

      4.21 stars rating. Excellent. 661 reviews
      Save 19%
      Strikethrough Rate:$99Discounted rate:$80USD/night
      Member Rate
    • 30
      Rodeway Inn South Houston

      20.45 mi from destination

      2.94 stars rating. Fair. 116 reviews
      Save 7%
      Strikethrough Rate:$59Discounted rate:$55USD/night
      Member Rate
    • 46
      Comfort Suites

      17.54 mi from destination

      3.48 stars rating. Good. 1653 reviews
      Save 7%
      Strikethrough Rate:$109Discounted rate:$101USD/night
      Member Rate
    • 19
      Sleep Inn & Suites Pearland - Houston South

      21.64 mi from destination

      3.97 stars rating. Good. 647 reviews
      Save 10%
      Strikethrough Rate:$74Discounted rate:$67USD/night
      Member Rate
    • 36
      Comfort Suites Deer Park Pasadena

      22.08 mi from destination

      3.97 stars rating. Good. 563 reviews
      Save 15%
      Strikethrough Rate:$101Discounted rate:$86USD/night
      Member Rate
    • 28
      Quality Suites Houston Hobby Airport

      21.99 mi from destination

      3.95 stars rating. Good. 201 reviews
      $75USD/night
    • 30
      Comfort Inn & Suites

      19.84 mi from destination

      3.15 stars rating. Good. 185 reviews
      Save 7%
      Strikethrough Rate:$119Discounted rate:$111USD/night
      Member Rate
    • 32
      Quality Inn & Suites Galveston - Beachfront

      18.59 mi from destination

      4.04 stars rating. Very Good. 3091 reviews
      Save 10%
      Strikethrough Rate:$120Discounted rate:$108USD/night
      Member Rate
    • 55
      Quality Inn Pasadena - Houston East

      23.99 mi from destination

      3.84 stars rating. Good. 309 reviews
      Save 7%
      Strikethrough Rate:$84Discounted rate:$78USD/night
      Member Rate
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    • 2
      Seabreeze Hotel, Ascend Hotel Collection

      20.02 mi from destination

      No Reviews Yet
      Coming soonStart booking Dec 02, 2025

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    Good to know

    Number of hotels

    18 hotels in Santa Fe

    Highest Price

    $111

    Lowest Price

    $55

    Avg. rating

    3.4 (11778 reviews)