Hotels in Weslaco, TX – Choice Hotels

40
Comfort Inn & Suites Donna near I-2
4.86 mi from destination
3.99 stars rating. Good. 528 reviews
Save 10%
Strikethrough Rate:~~$91~~Discounted rate:$82USD/night
Member Rate
40
Quality Inn & Suites at The Outlets Mercedes/Weslaco
6.2 mi from destination
3.58 stars rating. Good. 199 reviews
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Strikethrough Rate:~~$79~~Discounted rate:$71USD/night
Member Rate
5
Rodeway Inn San Juan
10.55 mi from destination
3.91 stars rating. Good. 194 reviews
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Strikethrough Rate:~~$48~~Discounted rate:$43USD/night
Member Rate
50
Comfort Inn Edinburg South
13.39 mi from destination
4.13 stars rating. Very Good. 862 reviews
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Strikethrough Rate:~~$90~~Discounted rate:$81USD/night
Member Rate
32
Comfort Inn & Suites Pharr - McAllen
12.38 mi from destination
3.95 stars rating. Good. 876 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$77USD/night
Member Rate
33
AWARD WINNER
Country Inn & Suites by Radisson, Harlingen, TX
18.79 mi from destination
4.63 stars rating. Exceptional. 163 reviews
Save 7%
Strikethrough Rate:~~$109~~Discounted rate:$101USD/night
Member Rate
29
Comfort Suites McAllen Airport and La Plaza Mall
14.99 mi from destination
3.94 stars rating. Good. 579 reviews
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Strikethrough Rate:~~$105~~Discounted rate:$95USD/night
Member Rate
44
MainStay Suites Edinburg South
13.39 mi from destination
4.09 stars rating. Very Good. 309 reviews
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Strikethrough Rate:~~$120~~Discounted rate:$108USD/night
Member Rate
50
Cambria Hotel McAllen Convention Center
17.08 mi from destination
4.42 stars rating. Excellent. 1390 reviews
Save 7%
Strikethrough Rate:~~$144~~Discounted rate:$134USD/night
Member Rate
14
Quality Inn Harlingen
17.26 mi from destination
3.6 stars rating. Good. 537 reviews
Save 7%
Strikethrough Rate:~~$74~~Discounted rate:$69USD/night
Member Rate
34
Clarion Inn near McAllen Airport
15.05 mi from destination
3.23 stars rating. Good. 555 reviews
Save 5%
Strikethrough Rate:~~$65~~Discounted rate:$62USD/night
Member Rate
2
NEW TO CHOICE
Comfort Inn Near Medical Center
18.63 mi from destination
4.1 stars rating. Very Good. 253 reviews
Coming soonStart booking Jul 01, 2026

Experience the Rio Grande Valley of Weslaco, Texas

Weslaco, situated in the heart of the Rio Grande Valley, offers visitors subtropical climate and rich cultural heritage near the Mexican border in South Texas. The community features beautiful parks, cultural sites, and access to world-class birdwatching opportunities in one of America's premier birding destinations. Visitors can explore local museums, enjoy Mexican-American culture, or discover the area's agricultural heritage through citrus groves and farming operations. The nearby Santa Ana National Wildlife Refuge provides exceptional opportunities to observe diverse wildlife species. Choice Hotels provides accommodations that offer convenient access to Valley attractions while serving as a base for exploring South Texas border culture.