Book Boutique Hotels in Clayton, MO

MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
1.19 mi from Clayton, MO, US
3.2 stars rating. Good. 198 reviews
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Strikethrough Rate:~~$154~~Discounted rate:$146USD/night
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Quality Inn Saint Louis Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
6.02 mi from Clayton, MO, US
3.27 stars rating. Good. 3058 reviews
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Strikethrough Rate:~~$94~~Discounted rate:$89USD/night
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AWARD WINNER
Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
7.69 mi from Clayton, MO, US
4.73 stars rating. Exceptional. 1974 reviews
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Strikethrough Rate:~~$134~~Discounted rate:$127USD/night
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Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
7.1 mi from Clayton, MO, US
4.05 stars rating. Very Good. 183 reviews
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Strikethrough Rate:~~$143~~Discounted rate:$122USD/night
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Comfort Inn & Suites Hazelwood - St. Louis
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
9 mi from Clayton, MO, US
4.11 stars rating. Very Good. 1991 reviews
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Strikethrough Rate:~~$115~~Discounted rate:$104USD/night
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Comfort Inn & Suites Saint Louis Lafayette Square
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
6.64 mi from Clayton, MO, US
3.8 stars rating. Good. 117 reviews
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Strikethrough Rate:~~$164~~Discounted rate:$153USD/night
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Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
8.71 mi from Clayton, MO, US
3.41 stars rating. Good. 1470 reviews
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Strikethrough Rate:~~$88~~Discounted rate:$83USD/night
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Radisson Hotel St. Louis Downtown Convention Center
811 N 9th St,
St. Louis, MO, 63101, US
7.9 mi from Clayton, MO, US
1.44 stars rating. Fair. 63 reviews
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Strikethrough Rate:~~$159~~Discounted rate:$151USD/night
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Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
11.37 mi from Clayton, MO, US
3.53 stars rating. Good. 1348 reviews
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Strikethrough Rate:~~$116~~Discounted rate:$99USD/night
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AWARD WINNER
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
11.65 mi from Clayton, MO, US
4.64 stars rating. Exceptional. 655 reviews
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Strikethrough Rate:~~$169~~Discounted rate:$161USD/night
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MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
7.12 mi from Clayton, MO, US
3.91 stars rating. Good. 241 reviews
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Strikethrough Rate:~~$144~~Discounted rate:$123USD/night
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Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
17.07 mi from Clayton, MO, US
3.91 stars rating. Good. 2490 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$97USD/night
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Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
15.65 mi from Clayton, MO, US
4.07 stars rating. Very Good. 225 reviews
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Strikethrough Rate:~~$120~~Discounted rate:$114USD/night
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Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
10.63 mi from Clayton, MO, US
No Reviews Yet
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Strikethrough Rate:~~$265~~Discounted rate:$228USD/night
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Sleep Inn Saint Charles North
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
15.67 mi from Clayton, MO, US
3.08 stars rating. Fair. 1043 reviews
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Strikethrough Rate:~~$106~~Discounted rate:$100USD/night
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Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
11.71 mi from Clayton, MO, US
4.02 stars rating. Very Good. 2080 reviews
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Strikethrough Rate:~~$189~~Discounted rate:$180USD/night
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Quality Inn O'Fallon IL - St. Louis
1409 W US 50,
O Fallon, IL, 62269, US
21.13 mi from Clayton, MO, US
3.55 stars rating. Good. 931 reviews
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Strikethrough Rate:~~$89~~Discounted rate:$80USD/night
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Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
20.46 mi from Clayton, MO, US
4.23 stars rating. Excellent. 1263 reviews
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Strikethrough Rate:~~$113~~Discounted rate:$97USD/night
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Quality Inn & Suites Caseyville - St. Louis
2180 Patricia Dr.,
Caseyville, IL, 62232, US
15.9 mi from Clayton, MO, US
2.72 stars rating. Fair. 710 reviews
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Strikethrough Rate:~~$106~~Discounted rate:$100USD/night
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Comfort Suites Fairview Heights - St Louis
137 Ludwig Drive,
Fairview Heights, IL, 62208, US
18.81 mi from Clayton, MO, US
3.46 stars rating. Good. 1806 reviews
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Strikethrough Rate:~~$139~~Discounted rate:$119USD/night
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River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
9.1 mi from Clayton, MO, US
No Reviews Yet
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Strikethrough Rate:~~$305~~Discounted rate:$276USD/night
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Econo Lodge Inn & Suites Granite City - St. Louis
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
13.96 mi from Clayton, MO, US
3.44 stars rating. Good. 389 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$81USD/night
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Sleep Inn O'Fallon near I-64
140 Venita Drive,
O Fallon, IL, 62269, US
21.87 mi from Clayton, MO, US
3.37 stars rating. Good. 1343 reviews
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Strikethrough Rate:~~$79~~Discounted rate:$75USD/night
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Comfort Inn & Suites St. Louis-O'Fallon
8170 Veterans Memorial Pkwy,
O Fallon, MO, 63366, US
21.16 mi from Clayton, MO, US
3.68 stars rating. Good. 1914 reviews
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Strikethrough Rate:~~$104~~Discounted rate:$100USD/night
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The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
20.75 mi from Clayton, MO, US
2.88 stars rating. Fair. 104 reviews
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Strikethrough Rate:~~$149~~Discounted rate:$142USD/night
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Comfort Inn & Suites OFallon - St Louis Area
116 Regency Park,
O'Fallon, IL, 62269, US
21.86 mi from Clayton, MO, US
2.36 stars rating. Fair. 118 reviews
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Strikethrough Rate:~~$93~~Discounted rate:$84USD/night
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Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy,
Fairview Heights, IL, 62208, US
19.39 mi from Clayton, MO, US
3.55 stars rating. Good. 196 reviews
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Strikethrough Rate:~~$129~~Discounted rate:$123USD/night
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Quality Inn Pacific near Six Flags St. Louis
1400 West Osage St.,
Pacific, MO, 63069, US
25.42 mi from Clayton, MO, US
4 stars rating. Very Good. 658 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$107USD/night
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Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
20.68 mi from Clayton, MO, US
3.65 stars rating. Good. 863 reviews
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Strikethrough Rate:~~$134~~Discounted rate:$121USD/night
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Econo Lodge Inn & Suites Fairview Heights - St. Louis
305 Salem Place,
Fairview Heights, IL, 62208, US
19.36 mi from Clayton, MO, US
3.75 stars rating. Good. 319 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$77USD/night
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Comfort Inn Near Six Flags St. Louis
1320 Thornton St.,
Pacific, MO, 63069, US
25.33 mi from Clayton, MO, US
4.06 stars rating. Very Good. 1772 reviews
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Strikethrough Rate:~~$133~~Discounted rate:$126USD/night
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Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive,
Fairview Heights, IL, 62208, US
18.82 mi from Clayton, MO, US
3.21 stars rating. Good. 223 reviews
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Strikethrough Rate:~~$149~~Discounted rate:$134USD/night
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Comfort Inn Collinsville near St. Louis
8 Commerce Dr.,
Collinsville, IL, 62234, US
17.61 mi from Clayton, MO, US
4.2 stars rating. Excellent. 1961 reviews
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Strikethrough Rate:~~$215~~Discounted rate:$194USD/night
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Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd.,
Saint Louis, MO, 63146, US
6.66 mi from Clayton, MO, US
3.55 stars rating. Good. 3113 reviews
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Comfort Inn Edwardsville - St. Louis
3080 S. SR 157,
Edwardsville, IL, 62025, US
19.6 mi from Clayton, MO, US
4.16 stars rating. Very Good. 1373 reviews
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Boutique hotels

33 of 35 hotels in Clayton

Highest Price

$276

Lowest Price

$75

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33 Boutique hotels near Clayton, MO, US

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Good to know

33 of 35 hotels in Clayton

$276

$75

3.4 (36192 reviews)