Book Boutique Hotels in Clayton, MO

MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
1.92 km from Clayton, MO, US
3.2 stars rating. Good. 198 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$101USD/night
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Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
11.43 km from Clayton, MO, US
4.05 stars rating. Very Good. 184 reviews
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Strikethrough Rate:~~$93~~Discounted rate:$78USD/night
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Comfort Inn & Suites Hazelwood - St. Louis
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
14.48 km from Clayton, MO, US
4.1 stars rating. Very Good. 1993 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$75USD/night
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AWARD WINNER
Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
12.37 km from Clayton, MO, US
4.73 stars rating. Exceptional. 1988 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$111USD/night
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Comfort Inn & Suites Saint Louis Lafayette Square
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
10.69 km from Clayton, MO, US
3.78 stars rating. Good. 118 reviews
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Strikethrough Rate:~~$124~~Discounted rate:$115USD/night
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Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
14.02 km from Clayton, MO, US
3.41 stars rating. Good. 1470 reviews
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Strikethrough Rate:~~$77~~Discounted rate:$71USD/night
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Quality Inn Saint Louis Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
9.69 km from Clayton, MO, US
3.27 stars rating. Good. 3058 reviews
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Strikethrough Rate:~~$84~~Discounted rate:$78USD/night
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Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
18.3 km from Clayton, MO, US
3.53 stars rating. Good. 1348 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$71USD/night
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Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
18.85 km from Clayton, MO, US
4.02 stars rating. Very Good. 2081 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$101USD/night
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AWARD WINNER
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
18.75 km from Clayton, MO, US
4.64 stars rating. Exceptional. 658 reviews
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Strikethrough Rate:~~$135~~Discounted rate:$126USD/night
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River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
14.64 km from Clayton, MO, US
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Strikethrough Rate:~~$135~~Discounted rate:$117USD/night
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MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
11.47 km from Clayton, MO, US
3.91 stars rating. Good. 241 reviews
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Strikethrough Rate:~~$121~~Discounted rate:$101USD/night
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NEW TO CHOICE
Radisson Hotel St. Louis Downtown Convention Center
811 N 9th St,
St. Louis, MO, 63101, US
12.71 km from Clayton, MO, US
1.44 stars rating. Fair. 63 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$113USD/night
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Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
27.48 km from Clayton, MO, US
3.9 stars rating. Good. 2495 reviews
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Strikethrough Rate:~~$113~~Discounted rate:$92USD/night
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Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
17.1 km from Clayton, MO, US
No Reviews Yet
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Strikethrough Rate:~~$195~~Discounted rate:$168USD/night
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Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
25.19 km from Clayton, MO, US
4.06 stars rating. Very Good. 227 reviews
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Strikethrough Rate:~~$100~~Discounted rate:$93USD/night
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Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
32.92 km from Clayton, MO, US
4.23 stars rating. Excellent. 1264 reviews
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Strikethrough Rate:~~$97~~Discounted rate:$83USD/night
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Comfort Inn Collinsville near St. Louis
8 Commerce Dr.,
Collinsville, IL, 62234, US
28.34 km from Clayton, MO, US
4.2 stars rating. Excellent. 1962 reviews
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Strikethrough Rate:~~$140~~Discounted rate:$126USD/night
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Quality Inn O'Fallon IL - St. Louis
1409 W US 50,
O Fallon, IL, 62269, US
34.01 km from Clayton, MO, US
3.55 stars rating. Good. 934 reviews
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Strikethrough Rate:~~$68~~Discounted rate:$61USD/night
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Quality Inn & Suites Caseyville - St. Louis
2180 Patricia Dr.,
Caseyville, IL, 62232, US
25.59 km from Clayton, MO, US
2.72 stars rating. Fair. 711 reviews
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Strikethrough Rate:~~$74~~Discounted rate:$69USD/night
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Sleep Inn O'Fallon near I-64
140 Venita Drive,
O Fallon, IL, 62269, US
35.19 km from Clayton, MO, US
3.37 stars rating. Good. 1344 reviews
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Strikethrough Rate:~~$59~~Discounted rate:$55USD/night
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Sleep Inn Saint Charles North
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
25.22 km from Clayton, MO, US
3.08 stars rating. Fair. 1043 reviews
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Strikethrough Rate:~~$94~~Discounted rate:$88USD/night
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Econo Lodge Inn & Suites Fairview Heights - St. Louis
305 Salem Place,
Fairview Heights, IL, 62208, US
31.16 km from Clayton, MO, US
3.75 stars rating. Good. 319 reviews
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Strikethrough Rate:~~$71~~Discounted rate:$63USD/night
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Comfort Suites Fairview Heights - St Louis
137 Ludwig Drive,
Fairview Heights, IL, 62208, US
30.27 km from Clayton, MO, US
3.46 stars rating. Good. 1808 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$85USD/night
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Econo Lodge Inn & Suites Granite City - St. Louis
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
22.47 km from Clayton, MO, US
3.44 stars rating. Good. 389 reviews
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Strikethrough Rate:~~$80~~Discounted rate:$74USD/night
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Comfort Inn Edwardsville - St. Louis
3080 S. SR 157,
Edwardsville, IL, 62025, US
31.54 km from Clayton, MO, US
4.16 stars rating. Very Good. 1373 reviews
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Strikethrough Rate:~~$144~~Discounted rate:$130USD/night
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Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
33.28 km from Clayton, MO, US
3.65 stars rating. Good. 863 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$98USD/night
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Comfort Inn & Suites St. Louis-O'Fallon
8170 Veterans Memorial Pkwy,
O Fallon, MO, 63366, US
34.05 km from Clayton, MO, US
3.68 stars rating. Good. 1915 reviews
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Strikethrough Rate:~~$101~~Discounted rate:$94USD/night
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Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive,
Fairview Heights, IL, 62208, US
30.29 km from Clayton, MO, US
3.21 stars rating. Good. 223 reviews
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Strikethrough Rate:~~$101~~Discounted rate:$91USD/night
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Quality Inn Pacific near Six Flags St. Louis
1400 West Osage St.,
Pacific, MO, 63069, US
40.91 km from Clayton, MO, US
4 stars rating. Very Good. 659 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$89USD/night
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Comfort Inn Near Six Flags St. Louis
1320 Thornton St.,
Pacific, MO, 63069, US
40.77 km from Clayton, MO, US
4.06 stars rating. Very Good. 1772 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$102USD/night
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Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy,
Fairview Heights, IL, 62208, US
31.21 km from Clayton, MO, US
3.55 stars rating. Good. 196 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$104USD/night
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The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
33.4 km from Clayton, MO, US
2.88 stars rating. Fair. 104 reviews
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Strikethrough Rate:~~$149~~Discounted rate:$142USD/night
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Comfort Inn & Suites OFallon - St Louis Area
116 Regency Park,
O'Fallon, IL, 62269, US
35.18 km from Clayton, MO, US
2.36 stars rating. Fair. 118 reviews
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Strikethrough Rate:~~$81~~Discounted rate:$73USD/night
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Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd.,
Saint Louis, MO, 63146, US
10.72 km from Clayton, MO, US
3.55 stars rating. Good. 3113 reviews
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Good to know

Highest Price

$168

Lowest Price

$55

Avg. rating

34 Boutique hotels near Clayton, MO, US

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$168

$55

3.4 (36232 reviews)