Hotels in Clayton, MO – Choice Hotels

AWARD WINNER
Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
12.37 km from Clayton, MO, US
4.73 stars rating. Exceptional. 2048 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$111USD/night
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Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
11.43 km from Clayton, MO, US
4.07 stars rating. Very Good. 190 reviews
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Strikethrough Rate:~~$106~~Discounted rate:$86USD/night
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MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
1.92 km from Clayton, MO, US
3.15 stars rating. Good. 210 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$101USD/night
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Comfort Inn & Suites Hazelwood - St. Louis
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
14.48 km from Clayton, MO, US
4.1 stars rating. Very Good. 2005 reviews
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Strikethrough Rate:~~$101~~Discounted rate:$94USD/night
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Quality Inn Saint Louis Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
9.69 km from Clayton, MO, US
3.26 stars rating. Good. 3079 reviews
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Strikethrough Rate:~~$86~~Discounted rate:$80USD/night
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Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
14.02 km from Clayton, MO, US
3.41 stars rating. Good. 1480 reviews
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Strikethrough Rate:~~$74~~Discounted rate:$69USD/night
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Comfort Inn & Suites Saint Louis Lafayette Square
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
10.69 km from Clayton, MO, US
3.79 stars rating. Good. 126 reviews
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Strikethrough Rate:~~$129~~Discounted rate:$120USD/night
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Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
18.3 km from Clayton, MO, US
3.52 stars rating. Good. 1360 reviews
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Strikethrough Rate:~~$81~~Discounted rate:$68USD/night
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MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
11.47 km from Clayton, MO, US
3.92 stars rating. Good. 244 reviews
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Strikethrough Rate:~~$110~~Discounted rate:$89USD/night
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River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
14.64 km from Clayton, MO, US
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Strikethrough Rate:~~$155~~Discounted rate:$134USD/night
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Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
18.85 km from Clayton, MO, US
4.02 stars rating. Very Good. 2107 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$113USD/night
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AWARD WINNER
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
18.75 km from Clayton, MO, US
4.64 stars rating. Exceptional. 685 reviews
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Strikethrough Rate:~~$164~~Discounted rate:$153USD/night
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NEW TO CHOICE
Radisson Hotel St. Louis Downtown Convention Center
811 N 9th St,
St. Louis, MO, 63101, US
12.71 km from Clayton, MO, US
1.43 stars rating. Fair. 117 reviews
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Strikethrough Rate:~~$115~~Discounted rate:$109USD/night
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Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
17.1 km from Clayton, MO, US
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Strikethrough Rate:~~$125~~Discounted rate:$109USD/night
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Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
27.48 km from Clayton, MO, US
3.89 stars rating. Good. 2519 reviews
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Strikethrough Rate:~~$103~~Discounted rate:$93USD/night
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Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
25.19 km from Clayton, MO, US
4.05 stars rating. Very Good. 235 reviews
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Strikethrough Rate:~~$100~~Discounted rate:$93USD/night
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Comfort Inn Collinsville near St. Louis
8 Commerce Dr.,
Collinsville, IL, 62234, US
28.34 km from Clayton, MO, US
4.2 stars rating. Excellent. 1979 reviews
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Strikethrough Rate:~~$133~~Discounted rate:$119USD/night
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Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
32.92 km from Clayton, MO, US
4.23 stars rating. Excellent. 1280 reviews
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Strikethrough Rate:~~$95~~Discounted rate:$81USD/night
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Econo Lodge Inn & Suites Granite City - St. Louis
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
22.47 km from Clayton, MO, US
3.45 stars rating. Good. 394 reviews
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Strikethrough Rate:~~$73~~Discounted rate:$68USD/night
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Quality Inn O'Fallon IL - St. Louis
1409 W US 50,
O Fallon, IL, 62269, US
34.01 km from Clayton, MO, US
3.55 stars rating. Good. 954 reviews
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Strikethrough Rate:~~$69~~Discounted rate:$66USD/night
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Quality Inn & Suites Caseyville - St. Louis
2180 Patricia Dr.,
Caseyville, IL, 62232, US
25.59 km from Clayton, MO, US
2.7 stars rating. Fair. 721 reviews
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Strikethrough Rate:~~$74~~Discounted rate:$69USD/night
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Sleep Inn Saint Charles North
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
25.22 km from Clayton, MO, US
3.08 stars rating. Fair. 1048 reviews
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Strikethrough Rate:~~$92~~Discounted rate:$86USD/night
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Comfort Suites Fairview Heights - St Louis
137 Ludwig Drive,
Fairview Heights, IL, 62208, US
30.27 km from Clayton, MO, US
3.45 stars rating. Good. 1820 reviews
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Strikethrough Rate:~~$89~~Discounted rate:$80USD/night
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Comfort Inn Edwardsville - St. Louis
3080 S. SR 157,
Edwardsville, IL, 62025, US
31.54 km from Clayton, MO, US
4.16 stars rating. Very Good. 1384 reviews
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Strikethrough Rate:~~$141~~Discounted rate:$127USD/night
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Comfort Inn & Suites St. Louis-O'Fallon
8170 Veterans Memorial Pkwy,
O Fallon, MO, 63366, US
34.05 km from Clayton, MO, US
3.68 stars rating. Good. 1926 reviews
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Strikethrough Rate:~~$96~~Discounted rate:$89USD/night
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Econo Lodge Inn & Suites Fairview Heights - St. Louis
305 Salem Place,
Fairview Heights, IL, 62208, US
31.16 km from Clayton, MO, US
3.76 stars rating. Good. 326 reviews
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Strikethrough Rate:~~$75~~Discounted rate:$66USD/night
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Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
33.28 km from Clayton, MO, US
3.64 stars rating. Good. 867 reviews
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Strikethrough Rate:~~$104~~Discounted rate:$94USD/night
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Sleep Inn O'Fallon near I-64
140 Venita Drive,
O Fallon, IL, 62269, US
35.19 km from Clayton, MO, US
3.36 stars rating. Good. 1354 reviews
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Strikethrough Rate:~~$80~~Discounted rate:$74USD/night
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Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive,
Fairview Heights, IL, 62208, US
30.29 km from Clayton, MO, US
3.16 stars rating. Good. 238 reviews
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Strikethrough Rate:~~$105~~Discounted rate:$95USD/night
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Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy,
Fairview Heights, IL, 62208, US
31.21 km from Clayton, MO, US
3.51 stars rating. Good. 220 reviews
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Strikethrough Rate:~~$129~~Discounted rate:$123USD/night
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Quality Inn Pacific near Six Flags St. Louis
1400 West Osage St.,
Pacific, MO, 63069, US
40.91 km from Clayton, MO, US
4.01 stars rating. Very Good. 669 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$107USD/night
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Comfort Inn Near Six Flags St. Louis
1320 Thornton St.,
Pacific, MO, 63069, US
40.77 km from Clayton, MO, US
4.06 stars rating. Very Good. 1786 reviews
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Strikethrough Rate:~~$126~~Discounted rate:$113USD/night
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The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
33.4 km from Clayton, MO, US
2.89 stars rating. Fair. 113 reviews
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Strikethrough Rate:~~$149~~Discounted rate:$142USD/night
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Comfort Inn & Suites OFallon - St Louis Area
116 Regency Park,
O'Fallon, IL, 62269, US
35.18 km from Clayton, MO, US
2.34 stars rating. Fair. 127 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$77USD/night
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Clayton hotels by brand

Ascend Hotels

Comfort Inn Hotels

Comfort Suites Hotels

Country Inn Suites Hotels

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Number of hotels

34 hotels in Clayton

Highest Price

$153

Lowest Price

$66

Avg. rating

34 hotels near Clayton, MO, US

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Clayton hotels by brand

Good to know

34 hotels in Clayton

$153

$66

3.6 (33611 reviews)