Book Boutique Hotels in Clayton, MO | Choice Hotels

Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
18.3 km from Clayton, MO, USA
3.54 stars rating. Good. 1344 reviews3.54 stars rating. Good. 1344 reviews
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Strikethrough Rate:~~$84~~Discounted rate:$63USD/night
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Sleep Inn O'Fallon near I-64
140 Venita Drive,
O Fallon, IL, 62269, US
35.19 km from Clayton, MO, USA
3.39 stars rating. Good. 1322 reviews3.39 stars rating. Good. 1322 reviews
Book Now & Save 11%
Strikethrough Rate:~~$59~~Discounted rate:$53USD/night
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Stay Longer. Save More.
Say hello to WoodSpring Suites® hotels! Designed for longer stays, we offer contemporary suites with in-room kitchens and free WiFi. Plus, our affordable rates cost less per night when you stay a week, month or more.
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MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
1.92 km from Clayton, MO, USA
3.22 stars rating. Good. 166 reviews3.22 stars rating. Good. 166 reviews
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MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
11.47 km from Clayton, MO, USA
3.93 stars rating. Good. 234 reviews3.93 stars rating. Good. 234 reviews
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Radisson Hotel St. Louis Downtown Convention Center
811 N 9th St,
St. Louis, MO, 63101, US
12.71 km from Clayton, MO, USA
No Reviews YetNo Reviews Yet
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River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
14.64 km from Clayton, MO, USA
No Reviews YetNo Reviews Yet
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Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
17.1 km from Clayton, MO, USA
No Reviews YetNo Reviews Yet
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Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
12.37 km from Clayton, MO, USA
4.71 stars rating. Exceptional. 1836 reviews4.71 stars rating. Exceptional. 1836 reviews
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Comfort Inn & Suites
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
10.69 km from Clayton, MO, USA
3.81 stars rating. Good. 93 reviews3.81 stars rating. Good. 93 reviews
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Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd.,
Saint Louis, MO, 63146, US
10.72 km from Clayton, MO, USA
3.57 stars rating. Good. 3079 reviews3.57 stars rating. Good. 3079 reviews
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Comfort Inn & Suites St. Louis-Hazelwood
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
14.48 km from Clayton, MO, USA
4.12 stars rating. Very Good. 1977 reviews4.12 stars rating. Very Good. 1977 reviews
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Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
11.43 km from Clayton, MO, USA
4.07 stars rating. Very Good. 177 reviews4.07 stars rating. Very Good. 177 reviews
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Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
18.85 km from Clayton, MO, USA
4.03 stars rating. Very Good. 2067 reviews4.03 stars rating. Very Good. 2067 reviews
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Quality Inn Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
9.69 km from Clayton, MO, USA
3.27 stars rating. Good. 3023 reviews3.27 stars rating. Good. 3023 reviews
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Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
14.02 km from Clayton, MO, USA
3.41 stars rating. Good. 1451 reviews3.41 stars rating. Good. 1451 reviews
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Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
27.48 km from Clayton, MO, USA
3.92 stars rating. Good. 2443 reviews3.92 stars rating. Good. 2443 reviews
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Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
18.75 km from Clayton, MO, USA
4.65 stars rating. Exceptional. 571 reviews4.65 stars rating. Exceptional. 571 reviews
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Comfort Inn Collinsville near St. Louis
8 Commerce Dr.,
Collinsville, IL, 62234, US
28.34 km from Clayton, MO, USA
4.19 stars rating. Very Good. 1917 reviews4.19 stars rating. Very Good. 1917 reviews
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Quality Inn & Suites Caseyville - St. Louis
2180 Patricia Dr.,
Caseyville, IL, 62232, US
25.59 km from Clayton, MO, USA
2.73 stars rating. Fair. 705 reviews2.73 stars rating. Fair. 705 reviews
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Sleep Inn
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
25.22 km from Clayton, MO, USA
3.08 stars rating. 1021 reviews3.08 stars rating. 1021 reviews
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The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
33.4 km from Clayton, MO, USA
2.84 stars rating. Fair. 92 reviews2.84 stars rating. Fair. 92 reviews
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Comfort Suites Fairview Heights - St Louis
137 Ludwig Drive,
Fairview Heights, IL, 62208, US
30.27 km from Clayton, MO, USA
3.46 stars rating. Good. 1776 reviews3.46 stars rating. Good. 1776 reviews
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Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
33.28 km from Clayton, MO, USA
3.66 stars rating. Good. 855 reviews3.66 stars rating. Good. 855 reviews
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Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
25.19 km from Clayton, MO, USA
4.12 stars rating. Very Good. 207 reviews4.12 stars rating. Very Good. 207 reviews
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Comfort Inn Edwardsville - St. Louis
3080 S. SR 157,
Edwardsville, IL, 62025, US
31.54 km from Clayton, MO, USA
4.17 stars rating. Very Good. 1364 reviews4.17 stars rating. Very Good. 1364 reviews
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Comfort Inn & Suites OFallon - St Louis Area
116 Regency Park,
O'Fallon, IL, 62269, US
35.18 km from Clayton, MO, USA
2.33 stars rating. Fair. 100 reviews2.33 stars rating. Fair. 100 reviews
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Comfort Inn & Suites St. Louis-O'Fallon
100 Comfort Inn Court,
O Fallon, MO, 63366, US
34.05 km from Clayton, MO, USA
3.68 stars rating. Good. 1865 reviews3.68 stars rating. Good. 1865 reviews
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Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy,
Fairview Heights, IL, 62208, US
31.21 km from Clayton, MO, USA
3.13 stars rating. Good. 132 reviews3.13 stars rating. Good. 132 reviews
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Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive,
Fairview Heights, IL, 62208, US
30.29 km from Clayton, MO, USA
3.2 stars rating. Good. 219 reviews3.2 stars rating. Good. 219 reviews
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Quality Inn O'Fallon IL - St. Louis
1409 W US 50,
O Fallon, IL, 62269, US
34.01 km from Clayton, MO, USA
3.56 stars rating. Good. 925 reviews3.56 stars rating. Good. 925 reviews
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Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
32.92 km from Clayton, MO, USA
4.23 stars rating. Excellent. 1220 reviews4.23 stars rating. Excellent. 1220 reviews
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Comfort Inn Near Six Flags St. Louis
1320 Thornton St.,
Pacific, MO, 63069, US
40.77 km from Clayton, MO, USA
4.05 stars rating. Very Good. 1725 reviews4.05 stars rating. Very Good. 1725 reviews
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Econo Lodge Inn & Suites
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
22.47 km from Clayton, MO, USA
3.43 stars rating. Good. 373 reviews3.43 stars rating. Good. 373 reviews
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Econo Lodge Inn & Suites Fairview Heights - St. Louis
305 Salem Place,
Fairview Heights, IL, 62208, US
31.16 km from Clayton, MO, USA
3.74 stars rating. Good. 316 reviews3.74 stars rating. Good. 316 reviews
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Quality Inn Near Six Flags St. Louis
1400 West Osage St.,
Pacific, MO, 63069, US
40.91 km from Clayton, MO, USA
4 stars rating. Very Good. 653 reviews4 stars rating. Very Good. 653 reviews
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Good to know

Boutique hotels

35 hotels in Clayton

Highest Price

$63

Lowest Price

$53

Avg. rating

3.3 (35248 reviews)