Book Quality Hotels in Saint Charles, MO

Quality Inn Saint Louis Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
11.96 km from Saint Charles, MO, US
3.26 stars rating. Good. 3060 reviews
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Strikethrough Rate:~~$90~~Discounted rate:$86USD/night
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Quality Inn Foristell
12 Highway W,
Foristell, MO, 63348, US
40.97 km from Saint Charles, MO, US
4.21 stars rating. Excellent. 926 reviews
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Strikethrough Rate:~~$111~~Discounted rate:$90USD/night
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Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
12.64 km from Saint Charles, MO, US
3.41 stars rating. Good. 1471 reviews
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Strikethrough Rate:~~$102~~Discounted rate:$97USD/night
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Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
37.38 km from Saint Charles, MO, US
3.53 stars rating. Good. 1349 reviews
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Strikethrough Rate:~~$115~~Discounted rate:$98USD/night
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Quality Inn Pacific near Six Flags St. Louis
1400 West Osage St.,
Pacific, MO, 63069, US
40.96 km from Saint Charles, MO, US
4 stars rating. Very Good. 659 reviews
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Strikethrough Rate:~~$129~~Discounted rate:$116USD/night
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Below are additional hotels in the area that do not match your exact search criteria.

Sleep Inn Saint Charles North
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
5.82 km from Saint Charles, MO, US
3.08 stars rating. Fair. 1043 reviews
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Strikethrough Rate:~~$95~~Discounted rate:$90USD/night
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Econo Lodge Inn & Suites Fairview Heights - St. Louis
305 Salem Place,
Fairview Heights, IL, 62208, US
47.66 km from Saint Charles, MO, US
3.75 stars rating. Good. 320 reviews
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Strikethrough Rate:~~$100~~Discounted rate:$90USD/night
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Comfort Inn & Suites Hazelwood - St. Louis
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
10.88 km from Saint Charles, MO, US
4.1 stars rating. Very Good. 1993 reviews
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Strikethrough Rate:~~$130~~Discounted rate:$117USD/night
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Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
33.09 km from Saint Charles, MO, US
3.65 stars rating. Good. 865 reviews
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Strikethrough Rate:~~$144~~Discounted rate:$130USD/night
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Comfort Suites Fairview Heights - St Louis
137 Ludwig Drive,
Fairview Heights, IL, 62208, US
46.86 km from Saint Charles, MO, US
3.45 stars rating. Good. 1809 reviews
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Strikethrough Rate:~~$162~~Discounted rate:$139USD/night
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Comfort Inn Near Six Flags St. Louis
1320 Thornton St.,
Pacific, MO, 63069, US
40.77 km from Saint Charles, MO, US
4.06 stars rating. Very Good. 1774 reviews
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Strikethrough Rate:~~$146~~Discounted rate:$139USD/night
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Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
19.24 km from Saint Charles, MO, US
3.9 stars rating. Good. 2498 reviews
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Strikethrough Rate:~~$183~~Discounted rate:$148USD/night
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Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive,
Fairview Heights, IL, 62208, US
46.89 km from Saint Charles, MO, US
3.19 stars rating. Good. 225 reviews
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Strikethrough Rate:~~$168~~Discounted rate:$151USD/night
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Comfort Inn & Suites St. Louis-O'Fallon
8170 Veterans Memorial Pkwy,
O Fallon, MO, 63366, US
17.19 km from Saint Charles, MO, US
3.68 stars rating. Good. 1916 reviews
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Strikethrough Rate:~~$160~~Discounted rate:$155USD/night
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Comfort Inn Collinsville near St. Louis
8 Commerce Dr.,
Collinsville, IL, 62234, US
42.06 km from Saint Charles, MO, US
4.2 stars rating. Excellent. 1965 reviews
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Strikethrough Rate:~~$174~~Discounted rate:$157USD/night
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MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
20.5 km from Saint Charles, MO, US
3.19 stars rating. Good. 199 reviews
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Strikethrough Rate:~~$174~~Discounted rate:$165USD/night
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The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
33.19 km from Saint Charles, MO, US
2.9 stars rating. Fair. 105 reviews
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Strikethrough Rate:~~$179~~Discounted rate:$170USD/night
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Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
7.13 km from Saint Charles, MO, US
4.06 stars rating. Very Good. 229 reviews
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Strikethrough Rate:~~$179~~Discounted rate:$170USD/night
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Comfort Inn Edwardsville - St. Louis
3080 S. SR 157,
Edwardsville, IL, 62025, US
41.37 km from Saint Charles, MO, US
4.16 stars rating. Very Good. 1375 reviews
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Strikethrough Rate:~~$190~~Discounted rate:$171USD/night
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Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
20.84 km from Saint Charles, MO, US
4.23 stars rating. Excellent. 1265 reviews
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Strikethrough Rate:~~$205~~Discounted rate:$175USD/night
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AWARD WINNER
Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
26.48 km from Saint Charles, MO, US
4.73 stars rating. Exceptional. 1996 reviews
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Strikethrough Rate:~~$189~~Discounted rate:$180USD/night
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Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
8.6 km from Saint Charles, MO, US
4.05 stars rating. Very Good. 184 reviews
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Strikethrough Rate:~~$226~~Discounted rate:$193USD/night
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MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
8.58 km from Saint Charles, MO, US
3.91 stars rating. Good. 241 reviews
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Strikethrough Rate:~~$238~~Discounted rate:$203USD/night
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Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy,
Fairview Heights, IL, 62208, US
47.64 km from Saint Charles, MO, US
3.55 stars rating. Good. 197 reviews
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Strikethrough Rate:~~$220~~Discounted rate:$209USD/night
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Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
1.84 km from Saint Charles, MO, US
4.02 stars rating. Very Good. 2087 reviews
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Strikethrough Rate:~~$234~~Discounted rate:$222USD/night
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Comfort Inn & Suites Saint Louis Lafayette Square
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
29.25 km from Saint Charles, MO, US
3.79 stars rating. Good. 121 reviews
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Strikethrough Rate:~~$240~~Discounted rate:$224USD/night
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NEW TO CHOICE
Radisson Hotel St. Louis Downtown Convention Center
811 N 9th St,
St. Louis, MO, 63101, US
30.14 km from Saint Charles, MO, US
1.45 stars rating. Fair. 67 reviews
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Strikethrough Rate:~~$249~~Discounted rate:$237USD/night
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AWARD WINNER
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
1.28 km from Saint Charles, MO, US
4.64 stars rating. Exceptional. 664 reviews
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Strikethrough Rate:~~$259~~Discounted rate:$246USD/night
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River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
33.79 km from Saint Charles, MO, US
No Reviews Yet
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Strikethrough Rate:~~$345~~Discounted rate:$312USD/night
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Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
3.27 km from Saint Charles, MO, US
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$365USD/night
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Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd.,
Saint Louis, MO, 63146, US
10.01 km from Saint Charles, MO, US
3.55 stars rating. Good. 3113 reviews
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Econo Lodge Inn & Suites Granite City - St. Louis
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
31.29 km from Saint Charles, MO, US
3.44 stars rating. Good. 390 reviews
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Quality Inn & Suites Caseyville - St. Louis
2180 Patricia Dr.,
Caseyville, IL, 62232, US
42.27 km from Saint Charles, MO, US
2.71 stars rating. Fair. 712 reviews
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Good to know

Number of hotels

30 of 33 hotels in Saint Charles

Highest Price

$365

Lowest Price

$86

Avg. rating

5 hotels near Saint Charles, MO, US match your filters

Below are additional hotels in the area that do not match your exact search criteria.

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Good to know

30 of 33 hotels in Saint Charles

$365

$86

3.4 (34818 reviews)