Book Boutique Hotels in Roxana, IL

Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
5.47 mi from Roxana, IL, US
3.66 stars rating. Good. 860 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$89USD/night
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Comfort Inn Edwardsville - St. Louis
3080 S. SR 157,
Edwardsville, IL, 62025, US
6.38 mi from Roxana, IL, US
4.16 stars rating. Very Good. 1372 reviews
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Strikethrough Rate:~~$134~~Discounted rate:$121USD/night
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The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
5.49 mi from Roxana, IL, US
2.88 stars rating. Fair. 104 reviews
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Strikethrough Rate:~~$119~~Discounted rate:$114USD/night
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Comfort Inn Collinsville near St. Louis
8 Commerce Dr.,
Collinsville, IL, 62234, US
11.53 mi from Roxana, IL, US
4.2 stars rating. Excellent. 1959 reviews
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Strikethrough Rate:~~$144~~Discounted rate:$117USD/night
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Econo Lodge Inn & Suites Granite City - St. Louis
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
6.69 mi from Roxana, IL, US
3.44 stars rating. Good. 387 reviews
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Strikethrough Rate:~~$76~~Discounted rate:$72USD/night
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Comfort Inn & Suites Hazelwood - St. Louis
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
16.56 mi from Roxana, IL, US
4.11 stars rating. Very Good. 1990 reviews
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Strikethrough Rate:~~$94~~Discounted rate:$85USD/night
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Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
15.6 mi from Roxana, IL, US
3.41 stars rating. Good. 1469 reviews
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Strikethrough Rate:~~$74~~Discounted rate:$70USD/night
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Comfort Suites Fairview Heights - St Louis
137 Ludwig Drive,
Fairview Heights, IL, 62208, US
17.34 mi from Roxana, IL, US
3.46 stars rating. Good. 1805 reviews
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Strikethrough Rate:~~$129~~Discounted rate:$110USD/night
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Sleep Inn O'Fallon near I-64
140 Venita Drive,
O Fallon, IL, 62269, US
18.69 mi from Roxana, IL, US
3.37 stars rating. Good. 1343 reviews
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Strikethrough Rate:~~$69~~Discounted rate:$66USD/night
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Quality Inn O'Fallon IL - St. Louis
1409 W US 50,
O Fallon, IL, 62269, US
18.54 mi from Roxana, IL, US
3.55 stars rating. Good. 931 reviews
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Strikethrough Rate:~~$81~~Discounted rate:$77USD/night
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Quality Inn & Suites Caseyville - St. Louis
2180 Patricia Dr.,
Caseyville, IL, 62232, US
16.24 mi from Roxana, IL, US
2.72 stars rating. Fair. 710 reviews
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Strikethrough Rate:~~$74~~Discounted rate:$70USD/night
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Econo Lodge Inn & Suites Fairview Heights - St. Louis
305 Salem Place,
Fairview Heights, IL, 62208, US
17.42 mi from Roxana, IL, US
3.75 stars rating. Good. 319 reviews
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Strikethrough Rate:~~$71~~Discounted rate:$64USD/night
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AWARD WINNER
Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
27.52 mi from Roxana, IL, US
4.73 stars rating. Exceptional. 1969 reviews
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Strikethrough Rate:~~$139~~Discounted rate:$132USD/night
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Quality Inn Saint Louis Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
17.73 mi from Roxana, IL, US
3.27 stars rating. Good. 3056 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$81USD/night
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Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
27.29 mi from Roxana, IL, US
4.07 stars rating. Very Good. 225 reviews
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Strikethrough Rate:~~$129~~Discounted rate:$123USD/night
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Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
19.6 mi from Roxana, IL, US
4.05 stars rating. Very Good. 183 reviews
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Strikethrough Rate:~~$160~~Discounted rate:$137USD/night
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Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive,
Fairview Heights, IL, 62208, US
17.36 mi from Roxana, IL, US
3.21 stars rating. Good. 223 reviews
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Strikethrough Rate:~~$139~~Discounted rate:$125USD/night
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Comfort Inn & Suites Saint Louis Lafayette Square
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
18.22 mi from Roxana, IL, US
3.79 stars rating. Good. 116 reviews
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Strikethrough Rate:~~$139~~Discounted rate:$129USD/night
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AWARD WINNER
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
23.44 mi from Roxana, IL, US
4.64 stars rating. Exceptional. 652 reviews
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Strikethrough Rate:~~$199~~Discounted rate:$189USD/night
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Sleep Inn Saint Charles North
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
24.74 mi from Roxana, IL, US
3.09 stars rating. Fair. 1042 reviews
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Strikethrough Rate:~~$94~~Discounted rate:$89USD/night
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Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
20.88 mi from Roxana, IL, US
3.54 stars rating. Good. 1347 reviews
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Strikethrough Rate:~~$96~~Discounted rate:$82USD/night
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Comfort Inn & Suites OFallon - St Louis Area
116 Regency Park,
O'Fallon, IL, 62269, US
18.89 mi from Roxana, IL, US
2.36 stars rating. Fair. 118 reviews
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Strikethrough Rate:~~$85~~Discounted rate:$77USD/night
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Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy,
Fairview Heights, IL, 62208, US
17.29 mi from Roxana, IL, US
3.52 stars rating. Good. 193 reviews
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Strikethrough Rate:~~$129~~Discounted rate:$123USD/night
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NEW TO CHOICE
Radisson Hotel St. Louis Downtown Convention Center
811 N 9th St,
St. Louis, MO, 63101, US
16.36 mi from Roxana, IL, US
1.44 stars rating. Fair. 63 reviews
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Strikethrough Rate:~~$109~~Discounted rate:$104USD/night
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Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
23.57 mi from Roxana, IL, US
No Reviews Yet
$325USD/night
Fees included
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MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
19.59 mi from Roxana, IL, US
3.91 stars rating. Good. 241 reviews
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Strikethrough Rate:~~$221~~Discounted rate:$189USD/night
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MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
21.17 mi from Roxana, IL, US
3.21 stars rating. Good. 197 reviews
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Strikethrough Rate:~~$149~~Discounted rate:$142USD/night
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Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
23.82 mi from Roxana, IL, US
4.02 stars rating. Very Good. 2080 reviews
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Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd.,
Saint Louis, MO, 63146, US
23.03 mi from Roxana, IL, US
3.55 stars rating. Good. 3113 reviews
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River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
24.33 mi from Roxana, IL, US
No Reviews Yet
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Good to know

Boutique hotels

27 of 30 hotels in Roxana

Highest Price

$325

Lowest Price

$64

Avg. rating

27 Boutique hotels near Roxana, IL, US

Comfort Inn Alton near I-255

Comfort Inn Edwardsville - St. Louis

The Great Rivers, an Ascend Collection Hotel

Comfort Inn Collinsville near St. Louis

Econo Lodge Inn & Suites Granite City - St. Louis

Comfort Inn & Suites Hazelwood - St. Louis

Quality Inn Florissant-St. Louis

Comfort Suites Fairview Heights - St Louis

Sleep Inn O'Fallon near I-64

Quality Inn O'Fallon IL - St. Louis

Quality Inn & Suites Caseyville - St. Louis

Econo Lodge Inn & Suites Fairview Heights - St. Louis

Comfort Suites St. Louis - Sunset Hills

Quality Inn Saint Louis Airport

Country Inn & Suites by Radisson, St. Peters, MO

Comfort Inn St. Louis Airport

Country Inn & Suites by Radisson, Fairview Heights, IL

Comfort Inn & Suites Saint Louis Lafayette Square

Country Inn & Suites by Radisson, St. Charles Historic District

Sleep Inn Saint Charles North

Quality Inn & Suites near St. Louis and I-255

Comfort Inn & Suites OFallon - St Louis Area

Radisson Hotel Fairview Heights - St. Louis

Radisson Hotel St. Louis Downtown Convention Center

Hollywood Casino St Louis

MainStay Suites St. Louis Airport

MainStay Suites St. Louis - Galleria

Change your dates to book properties below.

Comfort Suites St Charles-St Louis

Comfort Inn St. Louis - Westport Event Center

River City Casino & Hotel

Other Roxana searches

Good to know

27 of 30 hotels in Roxana

$325

$64

3.3 (28067 reviews)