34 hotels near Clayton, MO, USA

34 hotels near Clayton, MO, USA

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    • 33

      AWARD WINNER

      Comfort Suites St. Louis - Sunset Hills

      7.69 mi from destination

      4.73 stars rating. Exceptional. 2086 reviews
      Save 7%
      Strikethrough Rate:$119Discounted rate:$111USD/night
      Member Rate
    • 30

      Comfort Inn St. Louis Airport

      7.1 mi from destination

      4.06 stars rating. Very Good. 193 reviews
      Save 19%
      Strikethrough Rate:$106Discounted rate:$86USD/night
      Member Rate
    • 38

      MainStay Suites St. Louis - Galleria

      1.19 mi from destination

      3.12 stars rating. Good. 216 reviews
      Save 7%
      Strikethrough Rate:$129Discounted rate:$120USD/night
      Member Rate
    • 32

      Comfort Inn & Suites Hazelwood - St. Louis

      9 mi from destination

      4.09 stars rating. Very Good. 2017 reviews
      Save 12%
      Strikethrough Rate:$92Discounted rate:$81USD/night
      Member Rate
    • 30

      Quality Inn Saint Louis Airport

      6.02 mi from destination

      3.26 stars rating. Good. 3088 reviews
      Save 7%
      Strikethrough Rate:$94Discounted rate:$87USD/night
      Member Rate
    • 36

      NEW TO CHOICE

      Comfort Inn & Suites Saint Louis Lafayette Square

      6.64 mi from destination

      3.81 stars rating. Good. 130 reviews
      Save 10%
      Strikethrough Rate:$149Discounted rate:$134USD/night
      Member Rate
    • 12

      Quality Inn Florissant-St. Louis

      8.71 mi from destination

      3.41 stars rating. Good. 1485 reviews
      Save 7%
      Strikethrough Rate:$84Discounted rate:$78USD/night
      Member Rate
    • 15

      River City Casino & Hotel

      9.1 mi from destination

      No Reviews Yet
      Save 18%
      Strikethrough Rate:$165Discounted rate:$135USD/night
      Member Rate
      Fees included
    • 34

      Comfort Suites St Charles-St Louis

      11.71 mi from destination

      4.02 stars rating. Very Good. 2124 reviews
      Save 7%
      Strikethrough Rate:$125Discounted rate:$117USD/night
      Member Rate
    • 21

      Quality Inn & Suites near St. Louis and I-255

      11.37 mi from destination

      3.52 stars rating. Good. 1362 reviews
      Save 7%
      Strikethrough Rate:$93Discounted rate:$86USD/night
      Member Rate
    • 26

      MainStay Suites St. Louis Airport

      7.12 mi from destination

      3.93 stars rating. Good. 245 reviews
      Save 16%
      Strikethrough Rate:$116Discounted rate:$97USD/night
      Member Rate
    • 52

      NEW TO CHOICE

      Radisson Hotel St. Louis Downtown Convention Center

      7.9 mi from destination

      1.44 stars rating. Fair. 124 reviews
      Save 5%
      Strikethrough Rate:$130Discounted rate:$124USD/night
      Member Rate
    • 25

      Hollywood Casino St Louis

      10.63 mi from destination

      No Reviews Yet
      Save 18%
      Strikethrough Rate:$155Discounted rate:$127USD/night
      Member Rate
      Fees included
    • 25

      AWARD WINNER

      Country Inn & Suites by Radisson, St. Charles Historic District

      11.65 mi from destination

      4.64 stars rating. Exceptional. 693 reviews
      Save 7%
      Strikethrough Rate:$204Discounted rate:$189USD/night
      Member Rate
    • 38

      Comfort Inn & Suites Chesterfield - St. Louis

      17.07 mi from destination

      3.89 stars rating. Good. 2526 reviews
      Save 10%
      Strikethrough Rate:$101Discounted rate:$91USD/night
      Member Rate
      Fees included
    • 31

      Econo Lodge Inn & Suites Granite City - St. Louis

      13.96 mi from destination

      3.46 stars rating. Good. 397 reviews
      Save 7%
      Strikethrough Rate:$69Discounted rate:$64USD/night
      Member Rate
    • 42

      Country Inn & Suites by Radisson, St. Peters, MO

      15.65 mi from destination

      4.05 stars rating. Very Good. 241 reviews
      Save 7%
      Strikethrough Rate:$102Discounted rate:$95USD/night
      Member Rate
    • 36

      Comfort Inn Collinsville near St. Louis

      17.61 mi from destination

      4.2 stars rating. Excellent. 1991 reviews
      Save 19%
      Strikethrough Rate:$136Discounted rate:$110USD/night
      Member Rate
    • 25

      NEW TO CHOICE

      Radisson Hotel Fairview Heights - St. Louis

      19.39 mi from destination

      3.52 stars rating. Good. 230 reviews
      Save 5%
      Strikethrough Rate:$90Discounted rate:$86USD/night
      Member Rate
    • 28

      Sleep Inn & Suites O'Fallon MO - Technology Drive

      20.46 mi from destination

      4.23 stars rating. Excellent. 1289 reviews
      Save 19%
      Strikethrough Rate:$104Discounted rate:$84USD/night
      Member Rate
    • 31

      Quality Inn & Suites Caseyville - St. Louis

      15.9 mi from destination

      2.7 stars rating. Fair. 723 reviews
      Save 7%
      Strikethrough Rate:$73Discounted rate:$67USD/night
      Member Rate
    • 30

      Comfort Suites Fairview Heights - St Louis

      18.81 mi from destination

      3.44 stars rating. Good. 1831 reviews
      Save 10%
      Strikethrough Rate:$79Discounted rate:$71USD/night
      Member Rate
    • 29

      Sleep Inn Saint Charles North

      15.67 mi from destination

      3.08 stars rating. Fair. 1054 reviews
      Save 7%
      Strikethrough Rate:$90Discounted rate:$83USD/night
      Member Rate
    • 30

      Country Inn & Suites by Radisson, Fairview Heights, IL

      18.82 mi from destination

      3.17 stars rating. Good. 246 reviews
      Save 10%
      Strikethrough Rate:$92Discounted rate:$83USD/night
      Member Rate
    • 34

      Comfort Inn Edwardsville - St. Louis

      19.6 mi from destination

      4.16 stars rating. Very Good. 1391 reviews
      Save 10%
      Strikethrough Rate:$115Discounted rate:$104USD/night
      Member Rate
    • 25

      Quality Inn O'Fallon IL - St. Louis

      21.13 mi from destination

      3.54 stars rating. Good. 963 reviews
      Save 5%
      Strikethrough Rate:$75Discounted rate:$71USD/night
      Member Rate
    • 41

      Comfort Inn Alton near I-255

      20.68 mi from destination

      3.64 stars rating. Good. 872 reviews
      Save 10%
      Strikethrough Rate:$105Discounted rate:$95USD/night
      Member Rate
    • 28

      Econo Lodge Inn & Suites Fairview Heights - St. Louis

      19.36 mi from destination

      3.78 stars rating. Good. 333 reviews
      Save 10%
      Strikethrough Rate:$75Discounted rate:$68USD/night
      Member Rate
    • 31

      Comfort Inn & Suites St. Louis-O'Fallon

      21.16 mi from destination

      3.67 stars rating. Good. 1940 reviews
      Save 10%
      Strikethrough Rate:$105Discounted rate:$94USD/night
      Member Rate
    • 26

      Sleep Inn O'Fallon near I-64

      21.87 mi from destination

      3.36 stars rating. Good. 1359 reviews
      Save 7%
      Strikethrough Rate:$79Discounted rate:$73USD/night
      Member Rate
    • 30

      Comfort Inn & Suites OFallon - St Louis Area

      21.86 mi from destination

      2.36 stars rating. Fair. 132 reviews
      Save 10%
      Strikethrough Rate:$94Discounted rate:$85USD/night
      Member Rate
    • 31

      Quality Inn Pacific near Six Flags St. Louis

      25.42 mi from destination

      4 stars rating. Very Good. 673 reviews
      Save 10%
      Strikethrough Rate:$119Discounted rate:$107USD/night
      Member Rate
    • 35

      Comfort Inn Near Six Flags St. Louis

      25.33 mi from destination

      4.06 stars rating. Very Good. 1795 reviews
      Save 10%
      Strikethrough Rate:$135Discounted rate:$121USD/night
      Member Rate
    • 32

      NEW TO CHOICE

      The Great Rivers, an Ascend Collection Hotel

      20.75 mi from destination

      2.91 stars rating. Fair. 115 reviews
      Save 5%
      Strikethrough Rate:$133Discounted rate:$127USD/night
      Member Rate

    Discover the Suburban Elegance of Clayton, Missouri

    Clayton, an affluent suburb of St. Louis, offers visitors sophisticated urban amenities combined with beautiful residential neighborhoods and excellent cultural attractions. The community features upscale shopping, fine dining, and well-maintained parks that provide peaceful retreats from city life. Visitors can explore the Shaw Park area, enjoy cultural events, or easily access nearby St. Louis attractions including museums, sports venues, and entertainment districts. The area's blend of suburban charm and urban convenience creates perfect destinations for both relaxation and exploration. For accommodations, Choice Hotels provides convenient access to Clayton's attractions and greater St. Louis area amenities.

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    Clayton hotels by brand

    Good to know

    Number of hotels

    34 hotels in Clayton

    Highest Price

    $189

    Lowest Price

    $64

    Avg. rating

    3.6 (33864 reviews)