19 hotels near Defiance, MO, US

19 hotels near Defiance, MO, US

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    • Sleep Inn & Suites O'Fallon MO - Technology Drive

      1147 Technology Drive,
      O Fallon, MO, 63368, US
      6.99 mi from Defiance, MO, US
      4.23 stars rating. Excellent. 1264 reviews

      BOOK NOW AND SAVE 14%

      Strikethrough Rate:$89Discounted rate:$76USD/night
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    • Comfort Inn & Suites Chesterfield - St. Louis

      18375 Chesterfield Arpt. Rd.,
      Chesterfield, MO, 63005, US
      7.35 mi from Defiance, MO, US
      3.9 stars rating. Good. 2495 reviews

      BOOK NOW AND SAVE 18%

      Strikethrough Rate:$103Discounted rate:$84USD/night
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    • Comfort Inn & Suites St. Louis-O'Fallon

      8170 Veterans Memorial Pkwy,
      O Fallon, MO, 63366, US
      12.77 mi from Defiance, MO, US
      3.68 stars rating. Good. 1916 reviews

      BOOK NOW AND SAVE 7%

      Strikethrough Rate:$98Discounted rate:$91USD/night
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    • Quality Inn Pacific near Six Flags St. Louis

      1400 West Osage St.,
      Pacific, MO, 63069, US
      10.32 mi from Defiance, MO, US
      4 stars rating. Very Good. 659 reviews

      BOOK NOW AND SAVE 10%

      Strikethrough Rate:$99Discounted rate:$89USD/night
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    • Comfort Inn Near Six Flags St. Louis

      1320 Thornton St.,
      Pacific, MO, 63069, US
      10.19 mi from Defiance, MO, US
      4.06 stars rating. Very Good. 1772 reviews

      BOOK NOW AND SAVE 7%

      Strikethrough Rate:$112Discounted rate:$104USD/night
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    • Quality Inn Foristell

      12 Highway W,
      Foristell, MO, 63348, US
      15.91 mi from Defiance, MO, US
      4.21 stars rating. Excellent. 926 reviews

      BOOK NOW AND SAVE 19%

      Strikethrough Rate:$86Discounted rate:$70USD/night
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    • Country Inn & Suites by Radisson, St. Peters, MO

      3877 Veterans Memorial Pkwy,
      Saint Peters, MO, 63376, US
      16.01 mi from Defiance, MO, US
      4.07 stars rating. Very Good. 228 reviews

      BOOK NOW AND SAVE 7%

      Strikethrough Rate:$119Discounted rate:$111USD/night
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    • Comfort Inn & Suites Hazelwood - St. Louis

      7133 Douglas Palmer Place,
      Hazelwood, MO, 63042, US
      24.94 mi from Defiance, MO, US
      4.1 stars rating. Very Good. 1993 reviews

      BOOK NOW AND SAVE 12%

      Strikethrough Rate:$107Discounted rate:$95USD/night
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    • Comfort Inn St. Louis Airport

      11225 Lone Eagle Dr., Building A,
      Bridgeton, MO, 63044, US
      21.82 mi from Defiance, MO, US
      4.05 stars rating. Very Good. 184 reviews

      BOOK NOW AND SAVE 16%

      Strikethrough Rate:$107Discounted rate:$90USD/night
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    • AWARD WINNER

      Comfort Suites St. Louis - Sunset Hills

      3654 S. Lindbergh Blvd.,
      Saint Louis, MO, 63127, US
      20.86 mi from Defiance, MO, US
      4.73 stars rating. Exceptional. 1994 reviews

      BOOK NOW AND SAVE 7%

      Strikethrough Rate:$126Discounted rate:$117USD/night
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    • Comfort Suites St Charles-St Louis

      1400 S. Fifth Street,
      Saint Charles, MO, 63301, US
      18.1 mi from Defiance, MO, US
      4.02 stars rating. Very Good. 2083 reviews

      BOOK NOW AND SAVE 7%

      Strikethrough Rate:$129Discounted rate:$120USD/night
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    • AWARD WINNER

      Country Inn & Suites by Radisson, St. Charles Historic District

      1190 South Main Street,
      Saint Charles, MO, 63301, US
      18.51 mi from Defiance, MO, US
      4.64 stars rating. Exceptional. 662 reviews

      BOOK NOW AND SAVE 7%

      Strikethrough Rate:$259Discounted rate:$241USD/night
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    • Sleep Inn Saint Charles North

      150 Fountain Lakes Blvd.,
      Saint Charles, MO, 63301, US
      19.34 mi from Defiance, MO, US
      3.08 stars rating. Fair. 1043 reviews

      BOOK NOW AND SAVE 7%

      Strikethrough Rate:$94Discounted rate:$87USD/night
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    • Hollywood Casino St Louis

      777 Casino Center Drive,
      Maryland Heights, MO, 63043, US
      18.05 mi from Defiance, MO, US
      No Reviews Yet
      $165USD/night
      Fees included
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    • River City Casino & Hotel

      777 River City Casino Boulevard,
      Saint Louis, MO, 63125, US
      28.67 mi from Defiance, MO, US
      No Reviews Yet

      BOOK NOW AND SAVE 18%

      Strikethrough Rate:$135Discounted rate:$111USD/night
      Special Rate
      Fees included
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    • Quality Inn Saint Louis Airport

      10232 Natural Bridge Rd.,
      Saint Louis, MO, 63134, US
      23.79 mi from Defiance, MO, US
      3.26 stars rating. Good. 3059 reviews

      BOOK NOW AND SAVE 7%

      Strikethrough Rate:$84Discounted rate:$78USD/night
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    • MainStay Suites St. Louis Airport

      11225 Lone Eagle Dr., Building B,
      Bridgeton, MO, 63044, US
      21.82 mi from Defiance, MO, US
      3.91 stars rating. Good. 241 reviews

      BOOK NOW AND SAVE 16%

      Strikethrough Rate:$137Discounted rate:$115USD/night
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    • MainStay Suites St. Louis - Galleria

      8011 Galleria Pkwy,
      St. Louis, MO, 63117, US
      23.47 mi from Defiance, MO, US
      3.2 stars rating. Good. 198 reviews

      BOOK NOW AND SAVE 7%

      Strikethrough Rate:$109Discounted rate:$101USD/night
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    • Quality Inn Florissant-St. Louis

      55 Dunn Road,
      Florissant, MO, 63031, US
      25.85 mi from Defiance, MO, US
      3.41 stars rating. Good. 1470 reviews

      BOOK NOW AND SAVE 7%

      Strikethrough Rate:$88Discounted rate:$82USD/night
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    • Comfort Inn St. Louis - Westport Event Center

      12031 Lackland Rd.,
      Saint Louis, MO, 63146, US
      18.61 mi from Defiance, MO, US
      3.55 stars rating. Good. 3113 reviews
      Sold outfor your selected dates
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    Other Defiance searches

    Good to know

    Number of hotels

    20 hotels in Defiance

    Highest Price

    $241

    Lowest Price

    $70

    Avg. rating

    3.5 (25300 reviews)