Book Top Rated Hotels in Saint Charles, MO

AWARD WINNER
Country Inn & Suites by Radisson, St. Charles Historic District
1190 South Main Street,
Saint Charles, MO, 63301, US
0.8 mi from Saint Charles, MO, US
4.64 stars rating. Exceptional. 673 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$204~~Discounted rate:$190USD/night
Member Rate
See Availability
Comfort Suites St Charles-St Louis
1400 S. Fifth Street,
Saint Charles, MO, 63301, US
1.14 mi from Saint Charles, MO, US
4.02 stars rating. Very Good. 2099 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$134~~Discounted rate:$127USD/night
Member Rate
See Availability
Hollywood Casino St Louis
777 Casino Center Drive,
Maryland Heights, MO, 63043, US
2.03 mi from Saint Charles, MO, US
No Reviews Yet
BOOK NOW AND SAVE 13%
Strikethrough Rate:~~$145~~Discounted rate:$126USD/night
Member Rate
Fees included
See Availability
Comfort Inn & Suites Hazelwood - St. Louis
7133 Douglas Palmer Place,
Hazelwood, MO, 63042, US
6.76 mi from Saint Charles, MO, US
4.1 stars rating. Very Good. 2002 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$95~~Discounted rate:$88USD/night
Member Rate
See Availability
Country Inn & Suites by Radisson, St. Peters, MO
3877 Veterans Memorial Pkwy,
Saint Peters, MO, 63376, US
4.43 mi from Saint Charles, MO, US
4.05 stars rating. Very Good. 233 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$119~~Discounted rate:$111USD/night
Member Rate
See Availability
Comfort Inn St. Louis Airport
11225 Lone Eagle Dr., Building A,
Bridgeton, MO, 63044, US
5.34 mi from Saint Charles, MO, US
4.07 stars rating. Very Good. 187 reviews
BOOK NOW AND SAVE 10%
Strikethrough Rate:~~$107~~Discounted rate:$96USD/night
Member Rate
See Availability
Sleep Inn Saint Charles North
150 Fountain Lakes Blvd.,
Saint Charles, MO, 63301, US
3.62 mi from Saint Charles, MO, US
3.08 stars rating. Fair. 1048 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$96~~Discounted rate:$89USD/night
Member Rate
See Availability
Comfort Inn & Suites St. Louis-O'Fallon
8170 Veterans Memorial Pkwy,
O Fallon, MO, 63366, US
10.68 mi from Saint Charles, MO, US
3.68 stars rating. Good. 1923 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$93~~Discounted rate:$87USD/night
Member Rate
See Availability
Comfort Inn & Suites Chesterfield - St. Louis
18375 Chesterfield Arpt. Rd.,
Chesterfield, MO, 63005, US
11.95 mi from Saint Charles, MO, US
3.89 stars rating. Good. 2512 reviews
BOOK NOW AND SAVE 10%
Strikethrough Rate:~~$104~~Discounted rate:$94USD/night
Member Rate
Fees included
See Availability
Quality Inn Florissant-St. Louis
55 Dunn Road,
Florissant, MO, 63031, US
7.85 mi from Saint Charles, MO, US
3.41 stars rating. Good. 1478 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$82~~Discounted rate:$76USD/night
Member Rate
See Availability
Quality Inn Saint Louis Airport
10232 Natural Bridge Rd.,
Saint Louis, MO, 63134, US
7.43 mi from Saint Charles, MO, US
3.26 stars rating. Good. 3069 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$94~~Discounted rate:$87USD/night
Member Rate
See Availability
MainStay Suites St. Louis Airport
11225 Lone Eagle Dr., Building B,
Bridgeton, MO, 63044, US
5.33 mi from Saint Charles, MO, US
3.92 stars rating. Good. 242 reviews
BOOK NOW AND SAVE 16%
Strikethrough Rate:~~$114~~Discounted rate:$95USD/night
Member Rate
See Availability
Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive,
O Fallon, MO, 63368, US
12.95 mi from Saint Charles, MO, US
4.22 stars rating. Excellent. 1275 reviews
BOOK NOW AND SAVE 15%
Strikethrough Rate:~~$107~~Discounted rate:$91USD/night
Member Rate
See Availability
AWARD WINNER
Comfort Suites St. Louis - Sunset Hills
3654 S. Lindbergh Blvd.,
Saint Louis, MO, 63127, US
16.45 mi from Saint Charles, MO, US
4.73 stars rating. Exceptional. 2032 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$169~~Discounted rate:$157USD/night
Member Rate
See Availability
MainStay Suites St. Louis - Galleria
8011 Galleria Pkwy,
St. Louis, MO, 63117, US
12.74 mi from Saint Charles, MO, US
3.16 stars rating. Good. 204 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$119~~Discounted rate:$111USD/night
Member Rate
See Availability
Quality Inn Foristell
12 Highway W,
Foristell, MO, 63348, US
25.46 mi from Saint Charles, MO, US
4.21 stars rating. Excellent. 931 reviews
BOOK NOW AND SAVE 19%
Strikethrough Rate:~~$122~~Discounted rate:$99USD/night
Member Rate
See Availability
Comfort Inn Alton near I-255
11 Crossroads Ct.,
Alton, IL, 62002, US
20.56 mi from Saint Charles, MO, US
3.64 stars rating. Good. 867 reviews
BOOK NOW AND SAVE 10%
Strikethrough Rate:~~$111~~Discounted rate:$100USD/night
Member Rate
See Availability
Econo Lodge Inn & Suites Fairview Heights - St. Louis
305 Salem Place,
Fairview Heights, IL, 62208, US
29.61 mi from Saint Charles, MO, US
3.77 stars rating. Good. 324 reviews
BOOK NOW AND SAVE 12%
Strikethrough Rate:~~$75~~Discounted rate:$66USD/night
Member Rate
See Availability
Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive,
Fairview Heights, IL, 62208, US
29.14 mi from Saint Charles, MO, US
3.14 stars rating. Good. 236 reviews
BOOK NOW AND SAVE 10%
Strikethrough Rate:~~$97~~Discounted rate:$87USD/night
Member Rate
See Availability
Comfort Inn & Suites Saint Louis Lafayette Square
2625 Lafayette Ave,
Saint Louis, MO, 63104-2011, US
18.17 mi from Saint Charles, MO, US
3.78 stars rating. Good. 124 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$149~~Discounted rate:$139USD/night
Member Rate
See Availability
Comfort Suites Fairview Heights - St Louis
137 Ludwig Drive,
Fairview Heights, IL, 62208, US
29.12 mi from Saint Charles, MO, US
3.45 stars rating. Good. 1818 reviews
BOOK NOW AND SAVE 10%
Strikethrough Rate:~~$93~~Discounted rate:$84USD/night
Member Rate
See Availability
Comfort Inn Collinsville near St. Louis
8 Commerce Dr.,
Collinsville, IL, 62234, US
26.13 mi from Saint Charles, MO, US
4.2 stars rating. Excellent. 1974 reviews
BOOK NOW AND SAVE 10%
Strikethrough Rate:~~$154~~Discounted rate:$139USD/night
Member Rate
See Availability
River City Casino & Hotel
777 River City Casino Boulevard,
Saint Louis, MO, 63125, US
20.99 mi from Saint Charles, MO, US
No Reviews Yet
BOOK NOW AND SAVE 14%
Strikethrough Rate:~~$155~~Discounted rate:$134USD/night
Member Rate
Fees included
See Availability
Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Drive,
Cahokia, IL, 62206, US
23.23 mi from Saint Charles, MO, US
3.53 stars rating. Good. 1354 reviews
BOOK NOW AND SAVE 16%
Strikethrough Rate:~~$83~~Discounted rate:$69USD/night
Member Rate
See Availability
Econo Lodge Inn & Suites Granite City - St. Louis
3236 W. Chain of Rocks Road,
Granite City, IL, 62040, US
19.44 mi from Saint Charles, MO, US
3.44 stars rating. Good. 392 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$75~~Discounted rate:$70USD/night
Member Rate
See Availability
Comfort Inn Edwardsville - St. Louis
3080 S. SR 157,
Edwardsville, IL, 62025, US
25.71 mi from Saint Charles, MO, US
4.16 stars rating. Very Good. 1380 reviews
BOOK NOW AND SAVE 10%
Strikethrough Rate:~~$166~~Discounted rate:$149USD/night
Member Rate
See Availability
Quality Inn Pacific near Six Flags St. Louis
1400 West Osage St.,
Pacific, MO, 63069, US
25.45 mi from Saint Charles, MO, US
4 stars rating. Very Good. 666 reviews
BOOK NOW AND SAVE 10%
Strikethrough Rate:~~$106~~Discounted rate:$95USD/night
Member Rate
See Availability
NEW TO CHOICE
Radisson Hotel St. Louis Downtown Convention Center
811 N 9th St,
St. Louis, MO, 63101, US
18.73 mi from Saint Charles, MO, US
1.4 stars rating. Fair. 95 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$149~~Discounted rate:$142USD/night
Member Rate
See Availability
Comfort Inn Near Six Flags St. Louis
1320 Thornton St.,
Pacific, MO, 63069, US
25.33 mi from Saint Charles, MO, US
4.06 stars rating. Very Good. 1782 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$131~~Discounted rate:$122USD/night
Member Rate
See Availability
Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy,
Fairview Heights, IL, 62208, US
29.6 mi from Saint Charles, MO, US
3.51 stars rating. Good. 210 reviews
BOOK NOW AND SAVE 5%
Strikethrough Rate:~~$99~~Discounted rate:$94USD/night
Member Rate
See Availability
Quality Inn & Suites Caseyville - St. Louis
2180 Patricia Dr.,
Caseyville, IL, 62232, US
26.26 mi from Saint Charles, MO, US
2.7 stars rating. Fair. 721 reviews
BOOK NOW AND SAVE 7%
Strikethrough Rate:~~$74~~Discounted rate:$69USD/night
Member Rate
See Availability

Change your dates to book properties below.

Comfort Inn St. Louis - Westport Event Center
12031 Lackland Rd.,
Saint Louis, MO, 63146, US
6.22 mi from Saint Charles, MO, US
3.55 stars rating. Good. 3113 reviews
Sold outfor your selected dates
See Availability
The Great Rivers, an Ascend Collection Hotel
3559 College Avenue,
Alton, IL, 62002, US
20.63 mi from Saint Charles, MO, US
2.95 stars rating. Fair. 109 reviews
Sold outfor your selected dates
See Availability

Saint Charles hotels by brand

Ascend Hotels

Comfort Inn Hotels

Comfort Suites Hotels

Country Inn Suites Hotels

Good to know

Top-Rated hotels

33 hotels in Saint Charles

Highest Price

$190

Lowest Price

$66

Avg. rating

31 Top Rated hotels near Saint Charles, MO, US

Change your dates to book properties below.

Other Saint Charles searches

Saint Charles hotels by brand

Good to know

33 hotels in Saint Charles

$190

$66

3.4 (35073 reviews)